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Biomedical subjects

G Rizzo

Publications and source records attributed to G Rizzo.

At least 253 records · Page 14Linked to original sources
PubMed1977

Trimethoprim-sulphamethoxazole in the treatment of cholera. Comparison with tetracycline and chloramphenicol.

67 of the bacteriologically proved adult acute cholera patients have been examined in order to evaluate the efficacy of TM-SMX in comparison with tetracycline and chloramphenicol in the eradication of Vibrio cholerae from stools. Our results demonstrated that all three drugs sterilized the stools of all patients within 3 days with the exception of one case of TM-SMX's group, which had negative culture stools after 4 days. On the basis of our experience it can be emphasized that TM-SMX can support chloramphenicol and tetracycline in the antibacterial treatment of cholera with the advantage that the drug is efficacious with daily administrations.

Adult↗
PubMedDate not supplied

Umbilical artery velocity waveforms in early pregnancy: a transvaginal color Doppler study.

In a cross-sectional study, umbilical artery velocity waveforms were recorded in 214 low-risk pregnancies at 7 weeks to 16 weeks, menstrual age, by means of transvaginal color and pulsed Doppler ultrasonography. In all the cases studied, end diastolic velocities were absent until the 10th week. From this age onward end diastolic velocities were present in a percentage of pregnancies, progressively increasing with gestation and reaching 100% at 15 weeks. Similarly, the percentage of cardiac cycles in which end diastolic velocities were absent progressively decreased with advancing menstrual age. The normal range for the pulsatility index was constructed and a quadratic function was found to optimally fit its fall during gestation. No differences in pulsatility index values were found at these menstrual ages in 12 pregnancies that later developed intrauterine growth retardation and/or pregnancy-induced hypertension, suggesting that placental alterations causing abnormalities in umbilical velocity waveforms occur later in gestation.

Blood Flow Velocity↗
PubMedDate not supplied

Early fetal circulation in pregnancies complicated by retroplacental hematoma.

The objective of this study was to investigate the effects in early gestation of retroplacental hematomas on Doppler indices measured in different fetal vascular districts and to relate these changes, if any, to the volume of hematoma and pregnancy outcome. Thirty-eight pregnancies complicated by bleeding and ultrasonographic findings of retroplacental hematomas were considered for this study. Menstrual age ranged between 9 and 14 weeks. Blood flow velocity waveforms were measured in the umbilical artery, descending aorta, middle cerebral artery, and inferior vena cava. The pulsatility index in arterial vessels was calculated as well as the percentage reverse flow in the inferior vena cava. The values obtained were compared to previously constructed reference limits. No significant differences were found for any of the Doppler indices when the values obtained in pregnancies complicated by retroplacental hematomas were compared to the reference limits. Furthermore no significant relationships were found between the Doppler indices and either the size of hematoma or pregnancy outcome. In conclusion, retroplacental hematoma does not induce hemodynamic effects in the fetal circulation before 14 weeks, menstrual age. These data do not support the use of Doppler ultrasonography in early gestation for pregnancies complicated by bleeding and retroplacental hematomas.

Abortion, Spontaneous↗
PubMedDate not supplied

The fetal behavioural states: an ultrasonic study.

In order to accurately detect the fetal behavioural state, we simultaneously measured fetal heart rate and multiple fetal activities in 27 healthy pregnant women at 38 to 40 weeks of gestation. We ultrasonically identified gross body movements, breathing movements and micturition. Analysis of fetal heart rate allowed us to distinguish two different patterns of fetal behaviour: active and quiet phases. The frequency distribution of the analysed fetal events was significantly different in these two phases. These data suggest that a complete biophysical profile of the fetus is effective in differentiating behavioural states and may improve the predictive accuracy of fetal heart rate analysis alone.

Adult↗
PubMedDate not supplied

The development of fetal behavioural states: a longitudinal study.

In order to evaluate the development of fetal behavioural states a longitudinal study was performed on 35 healthy fetuses during the last trimester of pregnancy. Fetal heart rate (FHR), gross fetal body movements (FM), fetal eye movements (FEM), fetal breathing movements (FBM) and micturition were simultaneously studied at two-week intervals from 28 weeks gestation onwards. Well-defined fetal behavioural states were observed only after 36 weeks gestation. Between 28 and 36 weeks the quiet-activity cycle of FHR was always detected and some fetal biophysical activities seemed to become related around this cycle.

Eye Movements↗
PubMedDate not supplied

Modifications of ultradian and circadian rhythms of fetal heart rate after fetal-maternal adrenal gland suppression: a double blind study.

In order to verify whether fetal and maternal adrenal gland suppression induces effects on fetal behaviour, triamcinolone was administered to five healthy pregnant women at 35 weeks of gestation. Five patients of the same gestational age were used as control. Fetal heart rate (FHR) and fetal movements were recorded continuously over 2-h interval by means of cardiotocography. After 3 weeks (38 weeks of gestation) the recordings were repeated without drug administration. Cortisol, adrenocorticotropin hormone, 17 beta-estradiol and unconjugated estriol were measured at the same time every 2 h in maternal peripheral plasma. At 35 weeks we found a loss of circadian rhythms of the hormones investigated and modifications of ultradian and circadian patterns of FHR in the treated group with respect to the control. No differences in hormonal and biophysical parameters were found between the two groups after the end of treatment (38 weeks). These data suggest that the inhibition of fetal and maternal adrenal glands could cause modifications of FHR patterns.

Activity Cycles↗