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Biomedical subjects

G Persson

Publications and source records attributed to G Persson.

At least 73 records · Page 4Linked to original sources
PubMed1986

Low complication rate in extended wear of contact lenses. A prospective two-year study of non-medical high water content lens wearers.

The study was designed with the intention of reducing the risk of complications in extended wear. 214 eyes were fitted with Scanlens 75 high water content lenses for extended wear and followed for one year. The first 100 eyes to pass the 1-year check-up successfully were then followed for another year. The lenses used are high in oxygen transmissibility and at the same time rigid enough to allow good movements, which are considered very important. Thorough patient information, flat fits, frequent check-ups, and frequent lens replacements were principles applied to prevent discomfort and complications. Visual acuity and comfort were very good. Discomfort and unfavourable findings were low in frequency and healed without any sequelae whatsoever. The success rate was as good as 94.9% at 6 months, 92.1% at 1 year, and 88.4% at 2 years. The favourable results are considered to be due to the type of lens used as well as to the principles employed.

Adolescent↗
PubMed1986

Occurrence of cancer in socioeconomic groups in Sweden. An analysis based on the Swedish Cancer Environment Registry.

We wanted to examine the distribution of cancer by socioeconomic group in Sweden. For this purpose the 1960 Census population was followed up for the whole period 1961-79 by means of the Swedish Cancer Environment Registry. Cancer morbidity in five socioeconomic groups was analysed for each of 50 cancer sites. An association was found between several sites and particular socioeconomic groups. For instance, there are elevated rates of lung cancer and stomach cancer among blue collar workers; colon cancer and breast cancer among white collar workers and lip and stomach cancer among self-employed farmers. The overall cancer morbidity was close to the expected levels for all groups except self-employed farmers, who showed a marked deficit.

Adult↗
PubMed1985

A follow-up study of apicoectomized teeth with total loss of the buccal bone plate.

Opinions differ as to whether or not teeth with advanced marginal bone loss should be subjected to periapical surgery. The purpose of this retrospective investigation was to study the results after apicoectomy on teeth that showed total buccal bone loss at the time of the operation. The material consisted of twenty-seven teeth in 27 patients, fifteen males and twelve females, 23 to 63 years old at the time of the operation. The observation time varied from 0.5 to 7 years (mean, 3 years). Ten operations (37%) were regarded as successful, nine (33%) as uncertain, and eight (30%) as unsuccessful. The success rate was not so low that an apicomarginal communication should be regarded as a contraindication for apicoectomy. Apicoectomy should be performed, especially if the alternative is an otherwise unnecessary prosthetic reconstruction.

Adult↗
PubMed1985

Circannual changes in blood coagulation factors and the effect of warfarin on the hedgehog Erinaceus europaeus.

Levels of blood coagulation factors were measured monthly in hedgehogs kept at 20 degrees C under a natural-light schedule for 1 yr using prothrombin time and the P & P method. Hedgehogs display a circannual cycle of blood coagulation factors in the absence of temperature cues, with high levels corresponding to the active period and low levels corresponding to the hibernation period. Ten hedgehogs and ten guinea pigs were treated with clinical doses of warfarin and blood coagulation factors measured. Warfarin caused a similar decrease in vitamin K-dependent blood coagulation factors in both species.

Animals↗
PubMed1985

Agoraphobics and social phobics: differences in background factors, syndrome profiles and therapeutic response.

Seventy-three agoraphobic and 31 social phobic women, all rated unsuitable for insight-oriented psychotherapy, were compared regarding family and personal history, intelligence, personality and factors pertaining to the disorder. The same patients, with 11 men included in the social phobic group, were also compared regarding response to four randomly assigned types of treatment given over a 3 month period, with a 9 months' follow-up. The following differences were revealed: 1) Social phobias were associated with a higher social class of the parental home, higher education, higher scores on verbal intelligence, and a higher social class of the patient. 2) Social phobics scored higher on the personality factor, aggressive non-conformance, otherwise there were no differences in the personality factor. 3) Agoraphobias were associated with mother working outside home during the patient's childhood, neurotic symptoms in childhood, and current economic difficulties. Agoraphobics more often gave experience of death as a cause of the disorder. 4) Social phobias started at an earlier age. 5) Target phobia and the global rating were of equal severity in the two syndromes, but the agoraphobics had higher ratings on free anxiety and depersonalization. 6) Social phobics responded better to prolonged exposure in vivo, while agoraphobics responded better to supportive therapy of dynamic type, or to a simple basal therapy. Social phobics more often wanted the therapists to give advice and guidance.

Adult↗
PubMed1985

Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease. Comparison of beta-agonist therapy alone and in combination with a xanthine derivative, enprofylline or theophylline.

Long-term ambulatory Holter-monitoring was used to evaluate the arrhythmogenic effects of beta 2-agonist therapy, alone and in combination with a xanthine derivative, theophylline or enprofylline. Twenty patients (mean age 51 years) with mild-to-moderate obstructive lung disease (bronchial asthma or chronic bronchitis), but without concomitant ischemic heart disease were studied. Compared with beta 2-agonist therapy alone, both combined regimens were associated with a small but significant increase in the frequency of ventricular arrhythmias. Few serious arrhythmias were observed, however, and the clinical significance of these findings is thought to be minor. Although adenosine has been suggested to have an antiarrhythmic effect, a difference between theophylline and enprofylline in the effect on adenosine (theophylline but not enprofylline being an adenosine antagonist) would appear to be of less cardiac relevance in patients without ischemic heart disease.

Adrenergic beta-Agonists↗
PubMed1984

Risks, survival and trends of malignant melanoma among white and blue collar workers in Sweden.

All persons in Sweden, classified as white or blue collar workers in the 1960 Population Census, were followed up for the period 1961-1973 with regard to the occurrence of cancer. The SMRs were calculated for 50 tumour sites and it was found that the crude classification of occupations into white or blue collar workers was particularly important for malignant melanoma risk. The number of malignant melanoma cases among blue collar workers was significantly lower than expected while it was significantly higher than expected among the white collar workers. This was true for men as well as for women. The SMRs were calculated to be 87 and 141 (men) and 79 and 117 (women), respectively. Comparing the relative survival probabilities it was found that white collar workers had a higher probability of survival than blue collar workers. This might indicate that the difference in occurrence could be dependent on early detection as well as differential risk. The incidence of malignant melanoma is increasing faster than any other kind of tumour in Sweden. For the period 1961-1970 the incidence rate increased two-fold for blue collar workers and more than two-fold for white collar workers (men). In absolute terms the white collar workers in the age group 45-64 had an appreciably faster increase in incidence over this period compared to all other groups studied.

Adult↗
PubMed1984

Effects of four treatment methods on agoraphobic women not suitable for insight-oriented psychotherapy.

Seventy-three agoraphobic women rated unsuitable for insight-oriented psychotherapy, entered one of four randomly assigned types of treatment for 3 months. All patients received basal therapy in the form of standardized information, self-exposure instructions and anxiolytic medication. One group received this treatment only at monthly appointments (B). The others, in addition, received either therapist-directed prolonged exposure in vivo (PE), dynamically oriented supportive therapy (ST) or relaxation therapy (R). There was a 9-month follow-up period. All groups were about equally improved at the termination of treatment, with some advantage for PE and ST. At follow-up the ST group was more improved than the other groups, R was least improved, and PE showed some deterioration between the termination of treatment and the follow-up. ST, which took into account the overall adjustment as well as the symptoms, was thus the most successful treatment, but the superiority of the treatment did not manifest itself until at the end of the follow-up period.

Adolescent↗
PubMed1984

Effects of three non-insight-oriented treatment methods on agoraphobic women suitable for insight-oriented psychotherapy.

Twenty-three agoraphobic women rated suitable for insight-oriented psychotherapy received one of three randomly assigned non-insight-oriented types of treatment for 3 months and the effect was followed up after 9 months. All patients received basal therapy (B) in the form of standardized information, self-exposure instructions and anxiolytic medication. One group received this treatment only with monthly appointments. The others, in addition, received either therapist-directed prolonged exposure in vivo (PE) or relaxation therapy (R). The effects of insight-oriented psychotherapy could not be studied due to the small numbers in this group. All groups showed clinically relevant improvement, which indicates a favourable prognosis of patients suitable for insight-oriented psychotherapy irrespective of mode of treatment. However, since the PE group was least improved in some neurotic symptoms and had two treatment drop-outs and two cases of symptom substitution this mode of treatment cannot be recommended for insight-suitable patients. R patients came out favourably, which was contrary to the poor outcome with this therapy in patients not suitable for insight-oriented psychotherapy.

Adolescent↗
PubMed1984

Effects of four treatment methods on social phobic patients not suitable for insight-oriented psychotherapy.

Forty-two social phobic men and women, rated unsuitable for insight-oriented psychotherapy, received one of four randomly assigned types of treatment for 3 months. All patients received basal therapy (B) in the form of standardized information, self-exposure instructions, and anxiolytic medication. One group received this treatment only, with monthly appointments. The others, in addition, received either therapist-directed prolonged exposure in vivo, in some cases supplemented with exposure in imagination (PE), dynamically oriented supportive therapy (ST) or relaxation therapy (R). There was a 9 months' follow-up period. The phobia variables were more improved in the PE and ST groups than in the R and B groups at the termination of treatment. Although improvement had deteriorated somewhat in the PE group during follow-up, the improvement in target phobia was better than in the other groups. There were almost no improvements in the R and B groups. ST and PE groups also showed improved social function while the global rating showed most improvement in the PE group. The B group was not improved at all and the R group only showed a short-lived drop in muscular tension.

Adolescent↗
PubMed1984

Early interpersonal relations: experience of four treatment methods in phobic women.

One hundred and three phobic women not suitable for insight-oriented psychotherapy were randomized to either therapist-directed prolonged exposure in vivo (PE), supportive therapy of dynamic type (ST), relaxation therapy (R), or basal therapy (B). History taking was lengthy and included ratings of early interpersonal relations. These were combined into a scale with a range from 0, least favourable, to 13 most favourable. The patients filled in an inventory with regard to their experience of the therapist and the therapy at the beginning of the treatment, at midtreatment, and at the end of treatment, 3 months later. This inventory, the ETI, comprises different scales with ranges from least to most favourable experiences. The associations between the scales on the experience of early interpersonal relations and the ETI scales were studied. Most correlations were positive, indicating a similarity between the experience of early personal relations and the experience of the therapist and the therapy. The associations were significant at the start of therapy with B, and at the termination of therapy with R. These results are taken to indicate that when the desire for a personal relation with the therapist is frustrated the nature of the relation is interpreted according to the nature of the early relations. The fact that there was no association in ST indicates that when the patient is helped to express her reactions to current relations there is no need to fall back on early relations for the interpretation of the current ones. The opinion that it is possible to predict the character of the therapeutic relation from the character of early relations was supported.

Adult↗