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Biomedical subjects

G Pedio

Publications and source records attributed to G Pedio.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

Thin needle biopsy as a routine method for rapid diagnosis of neoplasms.

The present communication demonstrates the possibility of applying the "thin needle biopsy" as a routine method for rapid cytologic diagnosis of neoplasms. Systematically used in the examination of pulmonary, mammary, and thyroid tumors, the "thin needle biopsy" offers the following advantages: 1) decreased occurrence of so-called "false negative diagnoses"; 2) psychological relief for the patient; 3) decreased cost.

Biopsy, Needle↗
PubMedDate not supplied

Fine needle aspiration of the liver. Significance of hepatocytic naked nuclei in the diagnosis of hepatocellular carcinoma.

Fine needle aspiration (FNA) smears from 60 cases of histologically (34) or clinically (26) confirmed hepatocellular carcinomas were reviewed. In about 90% of the cases, the cytologic preparations contained clusters of malignant cells with variable degrees of hepatocytic features and a distinctive type of naked nuclei. These naked nuclei had features similar to those of the malignant hepatocytes, but with more evident atypia. They were numerous in about 75% of the cases and less frequent in 15%; in three cases, they were practically absent. All three cases of well-differentiated hepatocellular carcinomas presented with numerous naked nuclei with slight atypia. Flowerlike-configured naked nuclei were especially found in poorly differentiated hepatocellular tumors. Hepatocytic naked nuclei were rarely found in FNA smears from normal liver, metastases, cysts or degenerative, regenerative and inflammatory liver processes; when seen in these cases, they showed no atypia. The presence of atypical hepatocytic naked nuclei appears to be a very useful criterion for the diagnosis of hepatocellular carcinoma.

Adenoma, Bile Duct↗