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Biomedical subjects

G Pauli

Publications and source records attributed to G Pauli.

At least 343 records · Page 19Linked to original sources
PubMed1975

[Pulmonary aspergillosis. Apropos of 5 anatomo-clinical cases].

The authors report five cases of invading and diffuse pulmonary aspergillosis. Clinically they are characterized by a development in a still clear pulmonary field in patients with a lessened organic resistance and under corticosteroid treatment. Necrotic phenomenons occurred very quickly and prognosis was poor. Anatomically, foci were spreading, rapidly necrosing and contained Aspergillus. Diagnosis was based, besides etiological circumstances, on the presence of Aspergillus in sputum and of anti-aspergillus precipitins in serum.

Adrenal Cortex Hormones↗
PubMed1975

[Serum IgE Statistical study of 2000 measurements].

In a statistical analysis of more than 2000 IgE estimations, the authors corroborate the importance of this determination for diagnosis of asthma, eczema and rhinitis. Serum IgE levels are also elevated in parasitic diseases, and may be elevated in some other cases in which there are several disorders, such as cirrhosis and leukemia.

Asthma↗
PubMed1974

Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine monophosphate and cyclic adenosine monophosphate receptor protein for enzyme synthesis.

The strong repression of inducible synthesis of the enzymes of fatty acid degradation by glucose can be partially relieved by the addition of cyclic adenosine 3',5' monophosphate (cyclic AMP) to the growth medium. This reversal of the glucose effect by cyclic AMP is not observed in a mutant (K29) that is unable to grow on fatty acids as sole carbon source and that was found to synthesize low levels of several enzymes specified by the fad regulon. In a revertant selected for the ability to grow on oleate these effects are concomitantly relieved. By both genetic (co-transduction of the mutation with the strA locus) and biochemical experiments (an extract of the mutant strain does not show the cyclic AMP-dependent stimulation of the deoxyribonucleic acid-directed in vitro synthesis of the enzymes of the gal operon), it is demonstrated that the mutant lacks functional cyclic AMP receptor protein (CR protein). It is concluded that, like many other inducible enzyme systems, expression of the enzymes of the fad system requires cyclic AMP and the CR protein.

Acyltransferases↗
PubMedDate not supplied

Interferon induction by cell-cell interaction of HIV-infected monocytes/macrophages with lymphocytes.

An in vitro model of interferon (IFN) induction in HIV infection was established. IFN are induced by a cooperative mechanism, involving monocytes/macrophages (M/M) as well as lymphocytes. M/M non-lytically infected with HTLV-IIIB did not produce IFN, but were able to induce high titres of IFN activity when cocultured with peripheral blood lymphocytes, cell-cell contact being required. IFN alpha as well as IFN gamma were induced, as shown by neutralization with specific antisera. The antiviral activity of HIV-induced IFN was shown by infectivity reduction assays, and the immune-modulating capacity was demonstrated by activation of M/M leading to neopterin release.

Biopterins↗