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Biomedical subjects

G Pappalardo

Publications and source records attributed to G Pappalardo.

At least 73 records · Page 4Linked to original sources
PubMed1986

Surgical indications and techniques in the treatment of chronic pancreatitis.

Forty-six patients operated on for chronic pancreatitis are reported. 3 (6.4%) underwent splanchnicectomy, 29 (59.2%) Roux-en-Y side-to-side pancreaticojejunostomy, 17 (34.6%) resective procedures (8 left hemipancreatectomy, 5 subtotal pancreatectomy, 3 pancreaticoduodenectomy, 1 total pancreatectomy). Overall postoperative morbidity was 13%: 29.4% after excisional surgery and 3.4% after drainage procedures. One patient treated by subtotal pancreatectomy died because of a hepatorenal syndrome. All the 3 patients treated by splanchnicectomy required resection within two years. The best results were obtained by pancreaticojejunostomy. Drainage procedures represent the operations of choice for chronic pancreatitis as long as correct indications exist. Splanchnicectomy has been discarded as a mean of pain relief because of pain recurrence with time.

Adolescent↗
PubMed1986

Efficacy and stability of two chlorine-containing antiseptics.

Dakin's solution and a chloroxydizer in a hypertonic sodium chloride solution were tested for bacteriological and clinical effectiveness and stability. No real difference in effectiveness was observed between the two products; however, only the chloroxydizer showed satisfactory stability at 150 days under the test storage conditions.

Anti-Infective Agents, Local↗
PubMed1985

A new technique for ileoanal and coloanal anastomosis.

The following report includes a description of the technical details of a new surgical method for the total removal of the rectum while preserving the anal sphincter function. Seventeen patients including 11 patients with rectal carcinoma, two with diffuse polyposis involving the rectum, three with ulcerative colitis, and one with Crohn's disease of the colon and rectum have undergone operation by this method in the last 4 years. Clinical follow-up (mean 22 months) of these patients has demonstrated normal and continence for feces and gas. Postoperative manometric and electromyographic studies have also shown adequate sphincteric function. This method could be carried out either on patients in whom the total removal of the rectum is indicated or in patients with previous ileostomy or colostomy and a remaining rectal stump unsuitable for direct anastomosis.

Adult↗
PubMed1985

Surgical treatment of parotid gland tumors.

Fifty patients (27 females, 23 males) operated on for parotid neoplasms are reported. Eleven patients (22%) had benign tumors, 31 (62%) mixed tumors and 8 (16%) malignant tumors. Among patients with benign neoplasms, 10 (90,9%) were treated by enucleation (En.) and 1 (9,1%) by superficial parotidectomy (S.P.). Twenty-five patients (80,6%) with mixed neoplasms were operated on by total conservative parotidectomy (T.C.P.), 3 (9,7%) by S.P. and 3 (9,7%) by En. Three cases (37,5%) of malignant neoplasms were treated by T.C.P., and 5 (62,5%) by total demolitive parotidectomy (T.D.P.), associated to lateral lymphadenectomy in 3 patients. On the basis of a follow-up concerning 41 patients and of data from the literature, the authors report their present surgical approach for mixed tumors, underlining their preference for T.C.P., and limiting S.P. only to some selected cases.

Adolescent↗
PubMed1984

Intracolonic by-pass: a new technique to prevent anastomotic complications in colon and rectal surgery.

A new technique, the "intracolonic bypass" designed to prevent anastomotic complications after colonic and rectal resections is reported. It consists of a latex tube fixed to the intestinal wall above the anastomosis, which prevents the fecal stream from reaching the anastomotic site. The tube is retained until complete healing of the anastomosis and then excreted spontaneously through the anus. This new and simple technique avoids the disadvantages of a temporary diverting ileostomy or colostomy.

Colitis↗
PubMed1983

Follow-up results of a new colomyotomy in the treatment of diverticulosis.

In the present study, we report upon the preliminary results of our technique of myotomy--combined colon-myotomy at L shaped or transversal T shaped--which includes a simultaneous incision of both longitudinal and circular muscle fibers, avoiding a large bloody area. Ten patients have been operated upon by this method, the results of follow-up examination of seven patients who were given roentgenologic and motility studies for a maximum of 24 months being reported upon. It appears that the technique is quite safe, with no mortality or morbidity being observed in the first ten patients operated upon. Even functional results are most satisfactory. On the basis of this preliminary study, the technique seems to offer better results than do other types of colomyotomies currently being used.

Adult↗
PubMed1983

Intestinal absorption of S-adenosyl-L-methionine in humans.

S-adenosyl-L-methionine (SAM) has proven to be fairly stable in gastric and duodenal juices as well as in bile. It was, therefore, administered orally to six healthy subjects. No increase in SAM levels was observed in the systemic blood. SAM was then directly injected into a jejunal loop of nine patients undergoing cholecystectomy. SAM concentrations increased significantly in venous mesenteric and systemic blood. Infusions of methionine directly into the jejunum by the same method used for SAM did not induce any increase in SAM concentrations in the mesenteric or systemic blood.

Female↗
PubMed1982

Long-term results of Roux-en-Y hepaticojejunostomy and hepaticojejunoduodenostomy.

The results of the long-term follow-up of 202 patients with Roux-en-Y hepaticojejunostomy (Roux-en-Y HJ) and 19 with hepaticojejunoduodenostomy (HJD) are reported. The mortality, morbidity, and the incidence of postoperative anastomotic stenosis were comparable in both groups. One hundred forty patients with Roux-en-Y HJ and 19 with HJD were followed with barium meal and endoscopy. An incidence of 5% postoperative duodenal ulcer was noted in the first group, while no ulcer was seen in the patients with HJD. Preoperative and postoperative gastric acid secretion (basal acid secretion and maximal acid secretion) and serum gastrin levels (basal and after protein meal) were measured in 25 cases with Roux-en-Y HJ and 19 with HJD. The serum gastrin levels were similar initially and remained unchanged after surgery in both groups. However, the mean levels of basal and maximal acid output, which was similar before surgery in both groups, increased significantly only in patients who had Roux-en-Y HJ (p less than 0.001). In conclusion, HJD should be adopted as the preferred type of anastomosis in patients with benign pathology and long-life expectancy.

Adult↗
PubMed1982

New approach to esophagocardiomyotomy: report of forty cases.

The major postoperative complications of esophagocardiomyotomy (ECM) for achalasia are peptic esophagitis due to gastroesophageal reflux and recurrence. According to other authors, the incidence of postoperative esophagitis is 15% ot 25%. We report the results obtained in 40 patients treated by our own surgical technique, which is based on precise anatomic and physiopathological criteria. With this technique an ECM without esophagogastric mobilization is performed via a lower thoracotomy with partial perihiatal phrenotomy. There were no intraoperative or postoperative deaths. Two patients had postoperative basal pleurisy which was cured easily in a short time. In 36 of these patients, a follow-up ranging between 15 years and 6 months revealed a complete remission of dysphagia. The patients had significant and speedy improvement in their general condition. Seven patients had substernal pyrosis when lying down, but this was relieved in a few months in six of them. In only one patient did it persist for 4 years after the operation. Ph-manometric serial control studies performed in all the patients revealed, except in one case, normal pressure and pH values in the lower esophagus. Because of these results, we consider our ECM technique very effective in the treatment of achalasia.

Adult↗
PubMed1981

The Sda blood group in human secretions.

The authors, employing the absorption-inhibition technique, have further extended their experiments on human biologic fluids to investigate the sid substance. It was located in tears, sweat, nasal and tracheobronchial mucus, cerebrospinal fluid, and in aqueous humor while it was not found in bile (in accordance with its absence in liver tissue). The authors emphasize the significance that the verification of the Sid substance may assume in forensic investigations with the purpose of individual diagnosis in stains of the above mentioned secretions, particularly tears, sweat, and nasal mucus.

Adult↗