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Biomedical subjects

G Nielsen

Publications and source records attributed to G Nielsen.

At least 91 records · Page 5Linked to original sources
PubMed1972

Timeout duration and the suppression of deviant behavior in children.

The effects of three different timeout durations were investigated in a group of 20 retarded, institutionalized subjects. Each subject received 1, 15, and 30 min of timeout in a design that was counterbalanced in terms of the order in which timeout durations were presented. Displays of deviant behavior-such as aggression, tantrums, and self-destruction-were followed by periods of isolation in a timeout room. A reversal design was employed such that return-to-baseline periods were instituted after each timeout period. The overall effect of timeout was to reduce significantly the rate of deviant behavior. On the average, 15 and 30 min produced a 35% decrease in deviant behavior with little difference between the effectiveness of 15 and 30 min. The range of effects in all timeout conditions varied widely. The sequence in which the 1-min duration was presented effected the direction of its effect. When it preceded the use of longer durations, 1 min was most effective. As it came later in the sequence, its suppressive characteristics became less reliable.

Journal Article↗
PubMedDate not supplied

Prognostic indicators in alcoholic cirrhotic men.

The relationships between portal pressure, liver function and clinical variables on one hand and development of variceal hemorrhage and death on the other were investigated in 58 men with newly diagnosed alcoholic cirrhosis. Portal pressure was determined during hepatic vein catheterization as wedged minus free hepatic vein pressure, and median pressure was 14 mm Hg (range = 3 to 26 mm Hg). Fourteen of 31 patients (45%) had esophageal varices at upper gastrointestinal endoscopy (the size being considered large in nine patients). During follow-up (median = 31 months; range = 2 to 51 months), 12 patients (21%) developed variceal hemorrhage. Applying Cox's regression analysis, information about previous variceal bleeding (p = 0.0046), large varices at endoscopy (p = 0.012), hepatic vein pressure gradient (p = 0.0056) and indocyanine green clearance (p = 0.038) all contained significant prognostic information regarding development of variceal hemorrhage, even when easily obtained variables with known prognostic information were included [modified Child-Turcotte's criteria and incapacitation index (a weighted sum of days without normal health)]. During follow-up, 17 patients (29%) died. Applying Cox's regression analysis, large varices at endoscopy (p = 0.012) and hepatic vein pressure gradient (p = 0.019) contained significant prognostic information regarding death, in addition to the information contained in the modified Child-Turcotte's criteria and incapacitation index. In conclusion, prediction of prognosis in alcoholic cirrhotic men may be significantly improved by information about size of esophageal varices and level of portal pressure.

Adult↗