Search PubMedSearch

Biomedical subjects

G Neumann

Publications and source records attributed to G Neumann.

At least 181 records · Page 10Linked to original sources

Lipid metabolism of developing central nervous tissues in organotypic cultures. I. Lipid distribution and fatty acid profiles of the medium for rat brain cortex in vitro.

The distribution and concentration of lipid components of different media used for organotypic cultures of rat brain cortex have been measured quantitatively. Five cholesterol ester species have been fractionated from chicken embryonic extract. Their fatty acid profiles have been determined by combined gas liquid chromatography-mass spectrometry. The depletion characteristics of medium cholesterol esters and some fatty acids during development of brain cortex were not symmetrical. Polyunsaturated fatty acids of the medium were lowered prior to the saturated and monoenoic fatty acids. The phenomenon of depletion may be correlated with enhanced esterase activity mediated by the tissue.

Animals

[The epidemiology of lung cancer in the German Federal Republic, with special reference to regional differences (author's transl)].

11 per cent more men and 23 per cent more women died of lung cancer in the German Federal Republic during 1960-1971 than would have been the case if the age structure had remained unchanged. This increase involves exclusively (men) or predominantly (women) the over-65 years age group. It is still showing an upward trend in men and is most pronounced in the 45-74 age group. Mortality from lung cancer differs significantly between the Länder of the Federal Republic. It is highest for both men and women in the City States and is lowest in the less industrialized areas, particularly South Germany. This difference is presumably not entirely population: the particularly marked increase (especially in men) in the Saarland and North-Rhine-Westphalia-Länder with a predominance of heavy industry-suggests that occupational noxae may play a part.

Adult

[The costs of cancer screening (author's transl)].

By the cancer screening programme of the German legal health insurance 4,830,717 females were examined in 1973. The yield of cytologic "positive" cases has been 0.23 percent. The sum for finding one of these cases has been in the range from 14,388.-- DM to 16,132.--DM. As can be calculated by the available data on the incidence of cancer of the cervix uteri only about one third of these cases with "positive" findings can be a proven case of cancer (carcinoma in situ included). Thus one proven carcinoma of this site can be detected by the costs of 40,656.--DM to 80,586.--DM and this sum shows an increasing tendency. In spite of these high costs for the cancer detection programme the total expenses for early detection measures amounted only to 0.6 percent of the total expenditues of the legal health insurance in the first half-year 1974. The problem of a high rate of false-positive smears is discussed.

Adult