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Biomedical subjects

G Moulin

Publications and source records attributed to G Moulin.

At least 199 records · Page 11Linked to original sources
PubMed1981

[Respiratory complications in the course of treatment with D-penicillamine : alveolitis and bronchiolitis. A report of 4 cases (author's transl)].

D-penicillamine has proved to be an effective treatment of rheumatoid arthritis, but adverse effects of this drug are frequent. The authors report 4 cases of respiratory disease in the course of treatments with D-penicillamine for which the drug may probably be held responsible. Two patients presented with diffuse alveolitis which improved on stopping D-penicillamine. Two patients presented with rapidly progressive dyspnea; chest X-ray showed distended lungs; lung function tests showed severe airflow obstruction with air trapping : treatment with bronchodilators and corticosteroids was ineffective. Several cases of patients with such features have been reported during the last few years; pathologic studies which were performed disclosed bronchiolitis. Clinicians should be aware of the severity of this type of bronchiolitis and stop D-penicillamine immediately in patients presenting with early respiratory symptoms.

Aged↗
PubMed1980

[Pityriasis lichenoides (author's transl)].

A review of the literature concerning the pityriasis lichenoides and the study of 34 personal cases show that three main clinical patterns are found in pityriasis lichenoides: maculo-papular, leukomelanodermal, necrotic. The course is very variable: rarely seven weeks, more often seven months and sometimes seven years. The disease is issued from an angiitis including a mostly lymphocytic infiltration. The epidermis is secondarily invaded by inflammatory cells and shows focal parakeratosis. There is no specific immunologic disorder: immunohistopathologic study is generally normal (rarely IgM or C3 deposits); no circulating immune complex is found. Some patients improved with dapsone or photochemotherapy.

Fluorescent Antibody Technique↗
PubMed1978

Amylase activity of Torulopsis ingeniosa Di Menna.

Torulopsis ingeniosa DI MENNA was found to possess an alpha-amylase strongly attached to the cell wall, its pH optimum being at 5.5, optimum temperature at 50 degrees C, highly sensitive to thermal inactivation. The enzyme was found to be induced by starch but the synthesis is not subject to a glucose effect.

Amylases↗
PubMed1978

[Anetodermic cutaneous changes above Malherbe's tumors (author's transl)].

Clinical and histological anetoderma-like changes of the skin above Malherbe's tumor (pilomatricoma) may be of diagnostic value since they have been observed 5 times in a series of 22 consecutive cases. The histological study of 46 cases of Malherbe's tumor shows a high incidence of dermal atrophy and decrease of elastic fibers in reticular dermis above the tumor, a possible consequence of cellular infiltrates surrounding the tumor and seen in half our cases.

Adolescent↗
PubMed1977

[Familial palmo-plantar keratoderma with epidermolytic hyperkeratosis (author's transl)].

Three cases of palmo-plantar keratoderma coming from three different families are reported; Clinical features were those of Thost-Unna's disease; histo-pathological and ultrastructural aspects resembled those of the epidermolytic hyperkeratosis. The literature, 13 cases within 7 families with the same clinical and histopathological characteristics (though without study of the ultrastructure), have been reported. The authors propose to term "familial palmo-plantar keratoderma with epidermolytic hyperkeratosis", those cases of palmo-plantar keratoderma with dominant autosomal transmission and the histopathological aspects of the epidermolytic hyperkeratosis (Frost and Van Scott). The relationship of this disease with the naevus unius lateris and the bullous ichtyosiform hyperkeratosis are discussed. All three diseases could represent various phenotypical aspects of the same genetic abnormality of the keratinization process.

Adult↗
PubMed1977

[Reticulate erythema with mucinosis (R. E. M. Steigleder syndrome) (author's transl)].

We described a case similar to the four cases reported by Steigleder, Gartman and Linker in 1974 and entitled: "R.E.M. syndrome reticular erythematous mucinosis, a new entity?". In our case, clinical and histological findings were strictly identical to those previously reported. Furthermore, we detected no antibodies in the cutaneous lesions.

Adrenal Cortex Hormones↗
PubMed1976

[Chronic urticarial lesions and macroglobulinemia. Apropos of 5 cases].

The authors report 5 cases whose main characteristics appeared very similar. Constantly, they found the same skin signs, urticaria without pruritus, recurring over a long period. The latter was accompanied by a very high E.S.R. and immuno-electrophoresis showed, in all cases, an increase in monoclonal IgB, permitting one to make the diagnosis of macroglobulinemia. In four cases out of five, this clinical picture was accompanied by bony pain associated with radiological signs of condensation. The symptoms were accompanied by prolonged fever and lymphadenopathy. After being well tolerated for a long period, the disease may become worse and lead to death. Thus this seems to be a true disease entity?

Aged↗