Diffuse infiltrating retinoblastoma.
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Biomedical subjects
Publications and source records attributed to G Morgan.
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Twenty-six cases of lymphocytic tumour of the conjunctiva, which were originally classified as benign lymphoma and lymphosarcoma, were followed up for more than five years, They were then reclassified into non-disseminating and disseminating groups. Only when germinal follicles are present can a histological diagnosis of benign lymphoma be made. Moreover, it is only when lymphoblasts are seen to be infiltrating the tissues that a definitive diagnosis of lymphosarcoma can be made. The remaining tumours, which represent the large majority of lesions, show a very similar or identical histological picture, and a diagnosis of benignity or malignancy can only be made after a prolonged follow up. The possible nature of the non-disseminating lymphocytic tumours is briefly discussed.
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A series of 34 cases of embryonal sarcoma and embryonal rhabdomyosarcoma of the orbit has been placed histologically into three groups according to their maximum degree of differentiation at any stage: (a) embryonal sarcoma, (b) non-striated embryonal rhabdomyosarcoma, and (c) striated embryonal rhabdomyosarcoma. The patients were then followed up. This paper presents a summary of the clinical course of the whole series and an account of eight typical cases; the age and sex incidence and survival rates are shown and the histology, treatment, and prognosis are discussed.