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Biomedical subjects

G Miraglia

Publications and source records attributed to G Miraglia.

50 records · Page 3Linked to original sources

[The coarctation of the aorta in the adults. Long term results over 10 years (author's transl)].

From May 1964 through December 1976, at the Department of Cardiovascular Surgery, University of Padova, Medical School, 148 patients underwent surgery for coarctation of the aorta; 62 of them where 18 years of age or older. The Authors deal particularly with the clinical symptoms, the operative findings, the surgical technique and the postoperative complications of their series. The early (only three operative deaths) and late results are considered satisfactory, and are discussed according particularly to the type of surgical intervention.

Adult↗

Multiple lesions of the conduction system in a case of cardiac rhabdomyosarcoma with complex arrhythmias. An anatomic and clinical study.

Anatomic and electrocardiographic correlations in a case of primary cardiac rhabdomyosarcoma are examined. Interatrial and atrioventricular conduction disturbances were associated with multiple lesions involving the alleged internodal pathways, together with atrial-atrioventricular nodal connections. The clinicopathologic findings seem to be consistent with the hypotheses of the functional and morphologic value of Bachmann's fascicle, and of the inherent pathways of interatrial and internodal conduction in health and disease.

Adult↗

Epicillin: experimental chemotherapy, pharmacodynamics, and susceptibility testing.

Epicillin exhibits excellent therapeutic activity when administered orally or subcutaneously to mice infected with a variety of pathogenic bacteria. These included single strains of Streptococcus pyogenes, non-penicillinase-producing Staphylococcus aureus, Proteus mirabilis, Escherichia coli, Salmonella schottmuelleri, and Pseudomonas aeruginosa, strains of microorganisms selected as typical of those that frequently cause serious clinical infections. In oral chemotherapeutic comparisons of tetracycline, chloramphenicol, cephalexin, ampicillin, and epicillin, the latter, with but minor exceptions, exhibited activity comparable to that of most of the other antibiotics studied. Oral administration to mice of a loading dose of epicillin or ampicillin resulted in similar peak blood levels and decay curves. The concentration in urine and the excretion rates were significantly higher in epicillin than in ampicillin-treated animals. Presumptive evidence suggests that the inter-pretation of zone diameters obtained with 10-mug epicillin discs should be the same as is used for 10-mug ampicillin discs.

Acetamides↗