[Crohn's disease and pregnancy. Review of the literature and 1 case].
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Biomedical subjects
Publications and source records attributed to G Magnin.
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The authors report a new case where a women of 28 years of age started periods spontaneously in spite of having the phenotype of Turner's syndrome and a 45 X karyotype in her lymphocytes and fibroblasts. When she had been stimulated with Clomiphene it was even possible to prove that she had ovulated and produced a functional corpus luteum. No Barr bodies were to be found in the cells from her ovaries and the karotype did not suggest a mosaic which would normally explain this sort of state. All the same, it is difficult to see how any part of the basic follicles can persist in cases of monosomy 45 X if there is no mosaicism.
The authors studied the literature for similar findings in order to try to classify the different types of pneumoperitoneum when they had a case of pneumoperitoneum of genital origin. They then went on to study the mechanism by which these rare cases of genital pneumoperitoneum occurred: the insufflation or aspiration of air through the tubes, tubal antiperistalsis and uterine or vaginal perforations. From the clinical angle it is essential to eliminate pneumoperitoneum secondary to perforation of a hollow organ, and then to look for signs of peritonitis which only occur in genital pneumoperitoneum due to uterine perforation. The case usually cures spontaneously but recurrences are not uncommon. If there are no signs of peritonitis expectant treatment should usually be undertaken.
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