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Biomedical subjects

G Magnani

Publications and source records attributed to G Magnani.

At least 73 records · Page 4Linked to original sources

[Acquired immunodeficiency syndrome: epidemiological, clinical and immunological findings in risk groups in Parma].

Between August 1985 and June 1987, 809 subjects at risk for AIDS have been studied. 231 (28.5%) were seropositive for human immunodeficiency virus (HIV) antibodies. The seropositivity rate was 41% among drug addicts, 20.5% among homosexual/bisexual males, 19.7% among sexual partners of seropositive individuals. None of 62 subjects belonging to the health care personnel who interacted with seropositive patients and none of the 26 relatives of HIV-infected subject, have been found to be seropositive. Moreover the HIV seropositivity in the population of Parma was only 0.01%. Among the seropositive subjects, 155 (67.1%) were asymptomatic; 2 (0.8%) showed acute infection (a mononucleosis-like syndrome in both, associated with aseptic meningitis in one); 57 (24.6%) had PLG, 7 (3.4%) ARC, 9 (3.8%) full-blown AIDS (8 of these latter are dead).

Acquired Immunodeficiency Syndrome↗

[Ultrasonically-guided percutaneous puncture of Wirsung's duct].

A technique of ultrasonically guided percutaneous puncture of Wirsung's duct for pancreatic juice collection and radiological opacification is described. The equipment used is a linear array real-time transducer with a groove into which a metallic support provided with a guiding needle is attached. Once the depth at which the duct lies has been determined, a Chiba's needle is passed through the guiding needle and pushed up to the corresponding length. Pure pancreatic juice is then withdrawn for lactoferrin assay and a contrast medium is injected for pancreatography.

Biopsy, Needle↗

Interhemispheric differences in same versus different judgments upon presentation of complex visual stimuli.

An experiment is reported which was aimed at investigating interhemispheric differences upon tachistoscopic presentation of Same vs Different stimuli, i.e. pairs of 16-side Vanderplas and Garvin figures selected for their complexity, unfamiliarity and lack of verbalization. The right hemisphere was found to be faster and more accurate in Same judgements and the left hemisphere in Different judgements. These findings seem to further confirm the assumption that the right hemisphere would mostly use a holistic strategy and the left hemisphere an analytic strategy.

Adult↗

[Hepatitis B virus infection in a hospital population in Parma: implementation of a vaccination program].

An epidemiological survey of hepatitis B virus infection has been carried out in medical and paramedical employees of the Hospital of Parma, in order to identify high-risk groups and to estimate how many of subjects might be immunized with newly available but expansive vaccine. Radioimmunoassay procedures were used to detect the hepatitis B surface antigen (HBsAg) and the corresponding antibody (anti-HBs) in serum samples from 1682 hospital workers. Among these person tested, HBsAg was present in 57 (3.4%) and anti-HBs in 438 (26.3%); at least one of the two markers was found in 495 (29.4%). The prevalence of HBsAg and anti-HBs was related more closely to age, years and kind of occupation, than to clinical service (i.e. renal dialysis or medical services) and title (physician, nurse, laboratory technician, support staff.

Female↗

Effects induced by vincamine teprosilate on chronic cerebrovascular disease: preliminary results.

A group of 90 patients suffering from chronic cerebrovascular disease (CCVD) were selected on the basis of definite clinical criteria and pretests indicating a well-preserved general level of the higher functions. The purpose was to perform a clinical and neuropsychological assessment of CCVD sufferers during treatment with vincamine teprosilate (Teproside) for 90 days. Each selected patient was submitted to neurological examination and neuropsychological testing before treatment, after 45 days and at the termination of treatment. Neuropsychological examination included the reaction-time task, memory tests, verbal fluency test, trail making test, PM 38, MACL and STAI depression scales. Preliminary results are discussed and compared with previous data reported in the literature.

Aged↗

Results of radical nephrectomy with extensive lymphadenectomy for renal cell carcinoma.

Radical nephrectomy with extensive lymphadenectomy was performed by the same surgeon on 104 consecutive patients with renal cell carcinoma. No significant differences in over-all survival owing to age, sex and preoperative embolization were noted. Only extension of the disease proved to be important as a prognostic factor. In the light of the statistical analysis of this variable the prognosis for patients with renal cell carcinoma has been classified as 1) good--patients with tumors confined to the kidney, 2) intermediate--patients with perirenal fat involvement, lymph node metastases and venous extension, and 3) poor--patients with distant metastases.

Adenocarcinoma↗

Nyctohemeral pattern of serum LH, FSH and PRL in patients with myotonic dystrophy.

The nyctohemeral pattern of serum luteinizing (LH), follicle-stimulating hormone (FSH) and prolactin (PRL) in eight patients with myotonic dystrophy (MD) was studied. Gonadotropin patterns were classified as adult, pubertal or infantile. Six patients showed an adult pattern, whereas two had a pubertal or infantile pattern. A normal pattern of PRL secretion was found in seven patients and a blunted sleep-related hormonal increase was observed in one. Impaired hypothalamic control of pituitary secretion in MD is proposed as the cause for these findings.

Adult↗

Changes of pituitary secretion after long-term treatment with hydergine, in elderly patients.

The aim of this study was to evaluate the effects of long-term treatment with an ergot derivative, dihydroergotoxine mesylate (hydergine) 6 mg/day, on pituitary secretion on 10 elderly patients of both sexes. Samples were drawn at 120 min intervals during a 24 h period, before and after 1 month of therapy. Serum levels of Prl, GH, LH, FSH, TSH and cortisol were measured by RIAs. Hydergine induced a significant increase in the nocturnal serum GH peak. Conversely, no appreciable changes in the pattern of the other hormones studied were found. The observed endocrine effects could be due to the chronic dopaminergic stimulation induced by hydergine.

Age Factors↗

Influence of low doses of naloxone on pituitary secretion in man.

Naloxone 0.8 mg im administered to eight healthy subjects did not affect the serum levels of GH, LH, FSH, PRL, TSH and cortisol. Pretreatment with naloxone 0.8 mg increased TRH-induced TSH and PRL release in six healthy subjects. The same pretreatment caused an enhancement of haloperidol-induced PRL secretion in further other group of six subjects.

Adult↗

Prevention of child abuse and neglect through early diagnosis of serious disturbances in the mother-child relationship in Italy.

At the obstetrical clinic of Modena University and a family center of the same municipality during the first six months of 1980 a questionnaire based on "Risks of Child Abuse" by Kempe, Gray and others was administered to 33 expectant mothers during the third trimester of pregnancy, a few days after delivery, and a month and one-half after childbirth, for the purpose of examining the mother-child relationship. Two principal groups of "risk factors" which may lead to child abuse and neglect appeared: mothers with preceding personal and social experiences, and cases of medical intervention (e.g., prematurity, caesarean). Use of a questionnaire that permitted early diagnosis made possible help in establishing a good mother-child relationship in the first months of life. Such help can be given by the hospital and public centers both before and after birth.

Adaptation, Psychological↗

Evaluation of Prl secretion in elderly subjects.

Prl secretion was evaluated in 76 elderly patients (71-86z years) without endocrine disorders (38 men and 38 women) in basal conditions, after TRH, sulpiride and levodopa administration and during a 24 h period. An impaired Prl response to the administered drugs was found in the elderly women but not in the men. On the contrary, normal sleep-related serum Prl changes were found in the majority of the subjects studied. These results suggest that the pituitary gland can maintain a good Prl secretory pattern in the elderly.

Age Factors↗