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Biomedical subjects

G Lux

Publications and source records attributed to G Lux.

At least 145 records · Page 8Linked to original sources
PubMed1983

[The duodenum and Vater's papilla: tumors and tumor-like lesions--a clinico-pathologic discussion].

Tumors and tumor-like lesions of the duodenum and the Vater's ampulla are discussed in a clinical-pathological conference. Tumors and precancerous conditions are rarely found in the duodenum and the ampulla, nevertheless these areas should be investigated carefully during endoscopy of the upper gastrointestinal tract. About 12-15% of lesions described as tumors or tumor-like lesions are located in the duodenum. Histological findings of biopsy material from this region are the main topic of the conference. Incidence and differential diagnosis of the typical endoscopical and histological findings of the different tumors and tumor-like lesions are described.

Adenoma↗
PubMed1983

Transgastric sonography in pancreatic diseases.

The possibilities of a transgastric ultrasonic diagnosis of the pancreas and other organs are investigated in an initial series of 50 examinations using two different ultrasonic endoscopes.

Endoscopy↗
PubMed1983

[Retrograde pancreatic duct imaging and surgical tactics in hemorrhagic necrotizing pancreatitis. Preliminary report].

In patients with haemorrhagic necrotizing pancreatitis who are scheduled for surgery we have been carrying out a preoperative retrograde investigation of the pancreatic duct system for the past months. The results in, to date, ten patients revealed four different morphological findings of importance for the surgical tactic: 1. A normal pancreatic duct system with no signs of fistulae: only peripancreatic necrosectomy is required. - 2. Contrast medium leaks via a ductal fistula: left resection including the removal of the fistulous area must be done. - 3. Normal duct system with complete segmental parenchymal staining, representing total necrosis in this region: left resection of the pancreas. - 4. Duodenoscopically demonstrable perforation into the duodenum of a necrotic cavity in the head of the pancreas: conservative management only, no surgery, since this lesion resulting in drainage of the necrotic cavity into the bowel permits self-healing, while the site of the perforation within the necrotic wall cannot be dealt with by surgery. - The experience gained so far indicates that the surgical tactic can be determined with greater selectivity by the use of ERP.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1983

[Intragastric utilization of antacids following meals in relation to stomach emptying].

Gastric acid secretion and gastric emptying rate was measured using double marker method and continuous titration of a liquid peptone test meal. Titration rate was significantly reduced by 30 ml of an aluminiumhydroxide- and magnesiumhydroxide containing antacid compound (Maalox). Acidity of gastric contents was reduced over a period of 48.4 +/- 9.1 min (mean +/- SD; endpoint of titration pH 5.5) and 77.6 +/- 2.0 min (pH 3.5) (p less than 0.05). The histamine H2-receptor blocker Ranitidine (0.25 mg/kg b.w.) and the antimuscarinic agent Pirenzepine reduced titrable gastric acid secretion in a similar range, as far as the observation period of 90 min is concerned. Biosorbin MCT, a formula diet, stimulated gastric acid secretion half the amount of gastric acid secretion stimulated by the peptone meal. Gastric emptying rate was significantly reduced by formula diet, but not by either of the other compounds.

Adult↗
PubMed1982

Endoscopic ultrasonography--technique, orientation and diagnostic possibilities.

40 patients were examined by peroral endoscopic ultrasonography with two new prototypes (Prototype II and III, Olympus Optical Co., Tokyo, Japan). Indications were various intestinal diseases. Topographical orientation was facilitated by standard positions of the instrument. The organs identified included liver, gall bladder, common bile duct, pancreas, spleen and kidneys. Pathological lesions of the organs mentioned were characterized by the echo pattern known from external ultrasonography. At present endoscopic ultrasonography is not a routine method but may provide additional information to peroral endoscopy and external ultrasonography without replacing these methods.

Adult↗
PubMed1982

Influence of atropine, pirenzepine and cimetidine on nocturnal gastro-intestinal motility and gastric acid secretion.

The present study was performed to investigate the correlation between gastric H-ion-concentration and interdigestive motility (1) under basal conditions and (2) under the influence of pirenzepine, atropine and cimetidine. During the control period 6.5 (DZ1 5, DZ9 12) MMC's per 12-hour periods (69 +/- 7% gastrointestinal MMC's) were recorded. After administration of pirenzepine and the combination of pirenzepine and cimetidine almost exclusively gastrointestinal MMC's could be identified. On the other hand, atropine did not change the gastrointestinal/intestinal MMC ratio, but reduced total number of MMC's significancy (p less than 0.05). Percentage of observation time with antral pH greater than 4 was significantly increased by the combination of pirenzepine and cimetidine, but not by pirenzepine or cimetidine alone nor by atropine. There was a positive correlation between interdigestive cycle-length and percentage of time with antral pH greater than 4. The effect of pirenzepine on interdigestive motility (1) seems not to be mediated by the inhibition of gastric acid and (2) is different from the effect of atropine.

Adult↗
PubMed1981

[Hemorrhages from the pancreatic duct system: a severe complication in pancreatic diseases].

The incidence of hemorrhage into the gastrointestinal tract associated with formation of pancreatic pseudocysts or cystadenoma are very rare. When it does occur, it is almost always fatal. Two of our patients had intermittent episodes of upper gastrointestinal hemorrhage with severe anemia. After ERCP we performed subtotal resection of the pancreas in one case and total pancreatectomy in the other. The postoperative course was uncomplicated. Within the last 2 years no episodes of hemorrhage were seen.

Adult↗
PubMed1981

[Chronic pancreatitis and the neighboring organs].

The close topographic relationship between pancreas and the functional entity of the upper abdominal organs causes in about 20 percent of the patients with chronic pancreatitis alterations of the surroundings. In 531 patients compression of the common bile duct was found in 18.1%, duodenal stenosis in 17.7%, pleural thickening in 6.6%, splenic vein thrombosis in 5.1%, gastric outlet obstruction in 3.2% and colonic stenosis in 0.4%. In primary asymptomatic chronic pancreatitis these local complications may be the first hint to pancreatic disorders. Occasionally these changes demand operative interventions or alleviate the decision for resectional therapy.

Adult↗
PubMed1981

[Diagnosis of the irritable colon: manometric and myoelectric investigations (author's transl)].

Manometric investigations of patients with irritable colon show an undisturbed cyclic course of interdigestive motility studies of the rectosigmoid in patients with irritable colon show a spectrum of variable frequency of slow membrane potential changes with predominance of a frequency of 3/min. In addition, after a 1000 calorie test meal, patients with irritable colon showed a significantly prolonged increase of motility. As functional disturbances of irritable colon are mainly diagnosed by exclusion of organic changes, further development and rational use of colonic myoelectric methods promises future possibilities for objective diagnosis and control of treatment.

Adult↗
PubMed1981

Long-term follow-up after endoscopic sphincterotomy.

Endoscopic sphincterotomy has become a well-accepted procedure in choledocholithiasis and papillary stenosis. Long-term follow-up data covering an observation period of 7 years disclose that about 90% of the patients are either completely relieved of symptoms, or show marked improvement. Re-stenosis or recurrent concrements seem are events; in primary papillary stenosis, however, long-term results are less favorable.

Ampulla of Vater↗