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Biomedical subjects

G Lux

Publications and source records attributed to G Lux.

At least 91 records · Page 5Linked to original sources
PubMed1986

[Ultrasonic endoscopy. An assessment after 3 years].

A high-resolution ultrasound head at the tip of an endoscope, used in 259 examinations of 232 patients, has been demonstrated in general to fulfill the expectations placed on it as an important diagnostic tool.

Adolescent↗
PubMed1986

[Different healing tendencies of reflux esophagitis following omeprazole and ranitidine. Results of a German-Austrian-Swiss multicenter study].

The effectiveness of a single, morning oral dose of 40 mg omeprazole or a twice daily oral dose of 150 mg ranitidine was compared in a randomized endoscopically controlled double-blind trial at 37 clinics in Austria, Germany and Switzerland. A total of 178 out-patients in stages I-IVa (after Savary and Miller) were entered into the trial: 78 in stage I, 60 in stage II, 27 in stage III, and in 13 in stage IVa. As early as at the end of the third treatment week there was a significantly higher rate of complete healing or reduction into a lower stage with omeprazole than ranitidine (85% vs 67%; P less than 0.02). After six treatment weeks, healing tendency after omeprazole compared with ranitidine was 85% vs 45% (P less than 0.04). Omeprazole also brought earlier improvement in symptoms. The difference was statistically significant for heartburn (pyrosis): P less than 0.01. Both drugs were equally well tolerated and there were no clinically significant side-effects. This is the first demonstration that the ATPase inhibitor omeprazole is superior to the H2-receptor antagonist ranitidine in the treatment of reflux oesophagitis.

Administration, Oral↗
PubMed1986

Laser-resistant guide probe for laser treatment of endoscopically impassable tumour stenoses.

A laser-resistant guide probe that can be placed endoscopically, for use in the laser treatment of impassable tumour stenosis is described. It meets the necessary requirements such as low level of absorption of YAG laser light (1,064 nm wavelength), high thermal stability and low heat conduction. So far, the probe has been used complication-free, in four patients.

Esophageal Stenosis↗
PubMed1986

Laser lithotripsy of gallstone by means of a pulsed neodymium-YAG laser--in vitro and animal experiments.

Using a flashlamp pulsed Nd: YAG laser it is possible to destroy gallstones within a few seconds (median: 4 sec for stones less than 1.5 cc; 9.5 sec greater than 1.5 cc). In in vitro and animal studies it was shown that the median energy needed for stone destruction varies between 32 Joule for stones less than 1.5 cc and 80 Joules for stones greater than 1.5 cc. A 0.2 mm thick, flexible glass fibre makes possible retrograde laser lithotripsy by conventional endoscopes. Using a suitable technique the danger of thermal damage to tissue is small.

Animals↗
PubMed1986

Laser-induced shockwave lithotripsy of gallstones.

With the aid of a Q-switched Nd:YAG laser with energy transmission via a flexible glass fiber, it proves possible under laboratory conditions, to destroy gallstones reliably and reproducibly. Lithotripsy is effected mechanically via a laser-induced local shockwave.

Cholelithiasis↗
PubMed1986

Upper gastrointestinal bleeding as an unusual presentation of a duodenal carcinoid.

Carcinoid tumors may develop in any part of the gastrointestinal tract. They constitute 1.5% of all gastrointestinal tumors (1). The duodenum is one of the least common sites of this tumor, with a reported incidence varying between 0.2% and 8.9% (2, 3). We report on a case of a bleeding duodenal carcinoid in a patient who underwent bilateral nephrectomy for malignant hypertension.

Carcinoid Tumor↗
PubMed1986

Percutaneous endoscopic gastrostomy in patients with head and neck cancer.

A percutaneous endoscopic gastrostomy (PEG) was performed in 19 patients with cancers of head or neck. A commercially available gastrostomy set was used, but slight modifications were necessary in 4 patients. No serious complications were observed. The correct position and lack of any leak of gastric contents was verified by fluoroscopy in each case. These results confirm the experience of other groups, showing that the present technique of the PEG is reasonably safe and easy to perform.

Adolescent↗
PubMed1986

Palliative laser treatment of malignant stenoses in the upper gastrointestinal tract.

The present state of palliative laser therapy of inoperable malignant tumor stenoses in the upper gastrointestinal tract is reviewed. Indications, contraindications, several different sources of energy and forms of energy application, as also the various technical procedures, are discussed. Finally, the authors' experience with palliative laser therapy in 62 patients, and the results of an international inquiry covering data obtained in 1,359 patients, are presented.

Endoscopy↗
PubMed1986

Tumor stenoses of the upper gastrointestinal tract--therapeutic alternatives to laser therapy.

Alternatives to laser treatment of tumor stenoses of upper gastrointestinal tract include dilatation, implantation of bridging tubes, radiation therapy and chemotherapy. Based on the experience of 170 bridging tubes implanted and laser therapy in 70 patients with tumor stenoses (presented elsewhere) "tubes and laser" are compared. Complication rate, applicability in very proximal and distal stenoses are in favour of laser therapy, costs, hospitalisation time, possibility to occlude fistulae and short recurrence time after laser therapy are facts speaking for oesophageal bridging tubes. The question "tubes or laser" has to be answered by "tubes and laser" already.

Cisplatin↗
PubMed1986

Treatment of duodenal ulcer with low-dose antacids.

The aim of the present investigation was to compare the efficacy of a low-dose antacid (Maalox 70, 280 mmol/day) with that of the H2-receptor antagonist cimetidine (Tagamet, 200 mg three times daily and 400 mg/day) after 14 and 28 days in the treatment of duodenal ulcer. The prospective multicentre study included 171 patients with endoscopically confirmed duodenal ulcers. The patients were randomly assigned to the treatment groups with antacid containing Mg and Al hydroxide (M)(4 X 70 mmol/day; n = 86) or to the group receiving cimetidine (T) (1000 mg/day; n = 85). The two treatment groups were matched for age, sex, drinking and smoking habits, and drug use. Endoscopic examinations were carried out before the start of treatment and 14 days later. If the ulcer was still present at this time, the second endoscopic examination was done after a further 14 days. Endoscopically, the ulcer had healed at 14 days in 38.8% (M) and in 34.9% (T) and at 28 days in 80.0% (M) and 74.7% (T), respectively. The healing rate did not differ significantly between the two treatment groups. Complaints, measured as percentage of days per week with upper abdominal pain, were significantly reduced in both groups. No significant differences were found between the two treatment groups with regard to pain relief or side effects. Treatment had to be abandoned in one patient receiving antacid because of diarrhoea and in one patient receiving cimetidine because of the absence of any response.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1986

Malignant lesions of the upper gastrointestinal tract.

For malignant tumours of the upper gastrointestinal tract, endoscopic ultrasonography is used to assess their depth of penetration, infiltration of neighbouring organs, and metastatic spread to regional lymph nodes. Our experience so far in 124 echo-endoscopic examinations shows that the superior resolution of endoscopic ultrasonography makes possible a very accurate assessment of the depth of penetration of the tumour, and of lymphatic spread to the regional lymph nodes in oesophageal carcinoma. An assessment of infiltrative growth and differentiation from early carcinoma remains problematic.

Duodenal Neoplasms↗
PubMed1986

Endoscopic ultrasonography of the pancreas. Technical aspects.

Endoscopic ultrasonography was mainly developed to improve the diagnostic possibilities in pancreatic diseases. To standardize the technique and to evaluate the diagnostic possibilities of endoscopic ultrasonography, 76 examinations were performed in patients with suspected pancreatic disorders, using two types of ultrasonic device, a sector scanner and a linear array. The pancreatic region was visualized with good resolution, and a definite diagnosis was possible in most patients. Up to now endoscopic sonography has been used specially to supplement upper gastrointestinal tract endoscopy and external ultrasonography.

Endoscopy↗