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Biomedical subjects

G Ludwig

Publications and source records attributed to G Ludwig.

At least 91 records · Page 5Linked to original sources
PubMed1977

[Epididymitis].

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Adult↗
PubMed1977

[Epididymitis and fertility. Treatment results in acute unspecific epididymitis].

Spermiograms of 46 patients were examined 8 days, 4 weeks, 3 months, 6 months and 1 year after acute unilateral non-specific epididymitis. The treatment consisted in 24 cases besides antibiotic treatment with doxycycline in local infiltrations of the spermatic cord with 1% Scandicain solution. Primarily there was found an inhibiting effect on spermatogenesis. In more than 2/3 of the cases a varying oligoasthenospermia was shown 8 days after beginning of the infection. In the further course this disturbance of fertility improves; if local infiltration of the spermatic cord with 1% Scandicain solution is performed, the improvement is more evident. Still, there remain about 20% of the cases in which the fertility disturbance is so severe, that sterility results. One year after the beginning of the infection spermagglutinating antibodies could be shown only in 1 case. The seminal fluid fructose was controlled over 1 year following the beginning of infection and found to be normal in all cases.

Acute Disease↗
PubMed1976

[The significance of the columar structure of the stratum corneum for the effect of light on the skin].

Autologous full thickness skin autografts were carried out on 60 male guineapigs in such a way that the hair roots were destroyed. The light sensitivity of the skin towards UV B was then tested on the hairless skin by means of the Xenon lamp and the corresponding filter. Exploratory excisions were taken from another area of the graft and used to demonstrate the structure of the stratum corneum according to the method of Christophers. It could be shown that light erythema developed significantly less than when the columnar structure of the stratum cornuem was well developed.

Animals↗
PubMed1975

[Late results of nephropexy for nephroptosis according to a new indication schema].

A new schema for indicating operative treatment of nephroptosis is suggested. It was validated by an analysis of late results of 37 patients: 32 were completely free of symptoms, three still had the same symptoms but previously present pyelonephritis had healed. Two patients without long-term antibiotic treatment still had complaints and positive bacteriological findings. Non of the patients had haematuria. In two hypertensives the blood pressure had become normal.

Congenital Abnormalities↗
PubMed1975

[Optimal time for treating cryptorchism (author's transl)].

In a ten-year span (1950-1960) a total of 133 patients were operated upon for maldescent of testes. A follow-up enquiry traced 102, of whom 79 were re-examined. Maldescent had been unilateral in 71, bilateral in eight. All of the latter were infertile. In the others the fertility rate was the greater the younger the patient at the time of operation, best results being noted in those operated upon during the first or second year of life. Acquired testicular disorders seemed to play a minor role, while the normally descended contralateral testis was apparently damaged in an as yet undetermined manner (autoantigen-antibody reaction?) It is concluded that the optimal moment for operating on testicular maldescent is (at the latest) the end of the second year of life.

Adolescent↗
PubMed1975

[Early and late results after cryosurgical treatment of bladder neck obstructions (author's transl)].

We report on late results of 100 risk patients, who were operated by cryosurgical technique because of bladder neck obstructions. Detailed representation of complications. The primary mortality was 5%. Controls after one year showed good functional results on 80% of the patients. 60% of the patients had sterile urine, whereas only 17% of the male patients had no infection before the operation. As to the anatomical results we could talk of a cryoprostatectomy in 25% of the cases. Because of a 20% failure cryosurgery remains a palliative operation, which can only be carried out on risk patients. Because of little hemorrhagic diathesis and the possibility to perform this operation under local anesthesia cryosurgical operations on the other hand are suitable for patients, who cannot be anesthetised. Otherwise these patients had needed a permanent catheter. We prefer shorter freezing times of 3--4 min. Essentially we could show the same functional results as other authors, who preferred longer freezing times, until they reached a certain temperature in the prostatic capsule. By shorter freezing times on the contrary we could avoid secondary transurethral resections of larger necroses. New disturbed micturition after cryosurgical treatment of the prostate is unusual. The question of a later recidivation is of secondary importance because of the primary high morbidity rate of the selected number of cases.

Aged↗
PubMed1975

[Functional significance of the columnar structure of the stratum corneum and its occurrence on free autologous skin grafts].

The morphological presentation of the stratum corneum and simultaneously measurements of the alkali resistance and alkali neutralization time of the skin have been carried out in 26 guinea pigs. Whereas we could not demonstrate any association between the alkali neutralization time and the structure of the stratum corneum, a significantly better alkali resistance of the skin could be found when the columnar structure of the stratum corneum was most pronounced. The structure of the stratum corneum on full thickness skin autografts was also compared to that of normal skin in 26 animals. The columnar structure can be just as well pronounced on grafts as on normal skin. Significant differences between graft and normal skin could not be demonstrated but random samples showed that a disturbance in the columnar structure occurred more often in the grafts.

Alkalies↗