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Biomedical subjects

G Lose

Publications and source records attributed to G Lose.

157 records · Page 9Linked to original sources

Subcutaneous heparin in the treatment of interstitial cystitis.

Chronic interstitial cystitis (IC) is an inflammatory condition of the bladder of unknown aetiology. Clinically, IC is difficult to handle. Previously, we reported that administration of subcutaneous heparin has an immediate, ameliorating effect. We have now followed eight of the patients for one year or more, during which period they received subcutaneous heparin in doses varying from 5000 IU per day to 5000 IU 2-3 times a week. This treatment was found to have a long-term beneficial effect. No side effects were observed.

Adult↗

Regional ischemia due to compromised collateral circulation after arterial reconstruction.

Two cases of severe regional ischemia following aorto-femoral-popliteal vascular reconstruction are presented. Partial necrosis of the gluteal musculature occurred in one of the patients. Total necrosis of the proximal part of the thigh and the gluteal region developed in the other patient, despite preserved blood supply to the distal part of the leg. The available literature contains no previous reports of necrosis of musculature and skin from such cause. On the basis of these cases, the importance of preserving the pelvic-femoral collaterals, viz. rectal artery anastomosis and Hunterian anastomosis, is emphasized. Sufficient pelvic-femoral collaterals presumably account for the low incidence of gluteal claudication following aortofemoral bypass surgery.

Aorta, Abdominal↗

Clinical and urodynamic effects of norfenefrine in women with stress incontinence.

20 women with stress incontinence were treated with an alpha-adrenoceptor stimulating agent norfenefrine (Nevadral Retard) for 3 months. The mean dose administered was 60 mg given in slow-release tablets. Significant beneficial effect on the symptom and the 'sign' of stress incontinence was found as well as a significant increase in the maximum urethral closure pressure. 7 patients (35%) became subjectively and objectively continent. Only minor side effects were observed during treatment.

2-Hydroxyphenethylamine↗