Search PubMed⌕ Search

Biomedical subjects

G Lange

Publications and source records attributed to G Lange.

At least 145 records · Page 8Linked to original sources
PubMed1976

[Zinc oxide phosphate cement studies on the usefulness of Firmat].

The aim of the present investigations was to evaluate the Firmat zinc oxyphosphate cement in comparison with other brands, especially Adhesor normalhartend. The results obtained show that Firmat is a fast-setting phosphate cement which is not suited for polyhedral cavity linings. Time and material-consuming reworking is necessary. For temporary fillings, a temporary filling material should be used which is sufficiently solid, but easier to remove.

Drug Evaluation↗
PubMed1976

[Retrograde perfusion of the coronary sinus].

The investigations by Ratajczak-Pakalska showed peculiarities of cardiac venous circulation which make retrograde perfusion possible. Microcirculation is flowing in two directions, especially in diffuse cardiosclerosis. The results of the authors' animal experiments prove that the method of retrograde perfusion of coronary veins might be used ultimately in these cases.

Animals↗
PubMed1976

Detection of immune complexes in unheated sera by modified 125I-Clq binding test. Effect of heating on the binding of Clq by immune complexes and application of the test to systemic lupus erythematosus.

The 125I-Clq binding test was modified in order to allow for the detection of immune complexes in native unheated human serum. Indeed, heat-inactivation (56 degrees, 30 min) was found to reduce the Clq-binding activity of immune complexes mixed with native serum. This effect was not observed when EDTA was added to the native serum before mixing the immune complexes. The modified 125I-Clq binding test was performed in two steps: first, the tested native serum sample was incubated for 30 min at 37 degrees C with 0.13 M EDTA in order to prevent the integration of 125I-Clq into the intrinsic Clqrs complex, second, 125I-Clq and polyethylene glycol (final concentration 2.5%) were added to this mixture, and further incubated for 1 hr at 4 degrees C. Under these conditions, free Clq remained soluble whereas Clq bound to macromolecular complexes was precipitated. The competitive effect of intrinsic Clq and the interference of other substances such as DNA or bacterial LPS were very limited. The modified Clq binding test was applied to the clinical investigation of 44 patients with systemic lupus erythematosus; and increased Clq binding activity (Clq-BA) was observed in 91% of the samples. The level of Clq-BA was found to be significantly correlated to the DNA-binding capacity and to the decrease of the level of some complement components.

Antibodies↗
PubMed1976

[Cicatrical stenoses of the larynx (author's transl)].

16 cases of laryngeal (14 laryngo-tracheal) stenosis. 8 patients suffered from relatively uncomplicated subglottic cicatrices. These were treated after ventral cricotomy by excision, epithelial covering and tamponades or stents. In 7 cases with severe stenoses we performed a complete cricotomy and thyrotomy. The larynx was widened by implantation of a composite graft taken from the ear between the split posterior wall of the circoid (Rethi's maneouver). The following open treatment with tamponades or stents succeeded in 6 cases. Surgical correction of laryngeal stenoses should create a wide lumen with solid epithelial lining. Uncomplicated cases took 10 weeks, complicated cases 11 months in average until the laryngo-tracheostoma could be closed.

Accidents, Traffic↗
PubMed1976

[Functional results of tracheoplasties].

There is a direct correlation between airway resistance and residual tracheal lumen in tracheostenosis. Airway resistance has been recorded in 185 patients with tracheostenosis using body plethysmograph. High grade stenosis of the trachea is better diagnosed with body plethysmograph compared with direct inspection, a pertinent observation mainly in bordering cases. Tracheoplasties were performed in 74 patients using the body plethysmograph. Postoperative courses and functional results were observed. The average tracheal diameter was 8-9 mm at the end of our study with corresponding airway resistance of 24-34 mm H2O/l u. sec. These functional results reflect a good tolerance to average labour impound.

Airway Resistance↗
PubMed1975

[Inner-ear of monkeys under the influence of streptomycin-sulfate (author's transl)].

Eight monkeys were treated with 65 X 150 mg/kg Streptomycine-Sulfate per day given intramuscularly. Their vestibular reactions were investigated several times during and after (up to 7 1/2 months) the medication. Using nystagmography, a decrease of excitability could be realized as long as the drug was given. After the stop of the injections the excitability returned, mostly even up to the normal level. The most reliable vestibular reactions were the vestibular threshold, respectively duration and frequency of the postrotatory nystagmus. Additional medicaiton of Ozothin had some influence on the toxicity of Streptomycine towards the auditory system, but no effect at all regarding the vestibular reactions.

Animals↗
PubMed1975

Therapeutic problems in laryngo-tracheal stenoses.

History revealed iatrogenic injury (tracheostomy, intubation, artificial respiration) to be the reason for tracheal stenosis in each of our 32 cases (18 female, 14 male). So far 23 cases have been treated successfully and they live without a cannula; seven are still under treatment, while two patients died (severe heart-attack, spontaneous pneumothorax) and one refused further treatment. We were relatively successful in six cases of sleeve resection. All other 26 cases were treated by creating a tracheal groove, in which tracheal mucosa and skin of the neck were joined and the caudal end mostly kept open by using a pedicle skin flap. Intrathoracic stenoses require a sternotomy. An additional thyroidectomy and lateral traction to the tracheal walls by using loops out of the sternomastoid muscle became necessary in many cases and we obligatorily used tamponades of plastic inlay bolts, the average time of treatment being 8 months.

Adolescent↗
PubMed1975

[Bacteriological studies during conservative treatment of periapical inflammations].

32 teeth with the diagnosis of periapical osteitis (established by clinical and radiological examinations) were subjected to endodontic treatment (irrigation with hydrogen peroxide), the course of which was followed by bacteriological examinations. The timing of treatment termination depended solely upon clinical evaluation. The examination of smears taken before the last irrigation showed that 26 of the 32 root canals (81%) were germ-free; in 2 cases, an anaerobic infection was still extant; and in 4 cases, an aerobic infection was observed. The high percentage of root canals which were germ-free before the last irrigation testifies to the efficiency of hydrogen peroxide application for disinfecting root canals on the one hand, and demonstrates the good agreement between clinical and bacteriological findings on the other hand. The germs identified belonged mainly to the normal oral flora. Enterococci proved to be particularly resistant. The conservative treatment of periapical osteitis by means of root-canal disinfection with a hydrogen peroxide preparation ans subsequent root-canal filling with a calcium peroxide paste is recommended.

Calcium Hydroxide↗
PubMed1975

[Tympanoplasty after previous mastoidectomy (author's transl)].

Suppuration in ears suffering from a central perforation of the ear drum can frequently be stopped by mastoidectomy. This previous operation prepares ears for later tympanoplasty. 64 ears (55 patients) were treated by this way. Suppuration ceased in 47 ears. Spontaneous closure of the perforation could be seen in 7 cases. 23 ears underwent tympanoplastic procedures, always during a second intervention, 17 patients did not want further operations after the suppuration of their ears had stopped. Another 17 ears continued to reveal suppurative secretion in spite of mastoidectomy, mostly because of severe infection (resistant bacteria) or of insufficient mastoidectomy.

Adolescent↗
PubMed1975

[The puncture treatment in frontal sinusitis (author's transl)].

Patients suffering from acute or chronic frontal sinusitis should be treated by a drill-puncture of the anterior wall. A chronic cannula or a plastic tube is inserted and the sinusitis by this way influenced directly. In more than 60% of the cases the sinusitis can be cured and an operation is prevented. The procedure should be combined with a control of the nasal septum and the medial turbinate. Recidives of chronic frontal sinusitis after previous puncture should not a second time be treated using this method.

Acute Disease↗