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Biomedical subjects

G Ladurner

Publications and source records attributed to G Ladurner.

At least 127 records · Page 7Linked to original sources
PubMed1979

[The value of computer tomography in cerebrovascular accidents].

Computer-tomography investigations in 300 patients with cerebrovascular diseases are reported. The possibilities of computer-tomography for localization and follow-up of ischaemic attacks, intracerebral haematoma and subarachnoidal haemorrhages are described. Details of clinical and diagnostic importance of follow-up studies are presented together with examples of current pathological data.

Brain Ischemia↗
PubMed1979

[Classification and course of cerebral infarcts on computer tomography (author's transl)].

The typical computer tomographic signs of ischaemic cerebral infarct are discussed on the basis of 631 cases. Infarcts have three typical stages. Stage I, one week, fresh infarct with signs of oedema (space-occupying lesion with an unsharp margin, slightly reduced density, lack of contrast uptake). Stage II, second to fourth week, reduction in the oedema. Frequently very marked contrast enhancement of the cortex and basal nuclei. Stage III, later than four weeks. Development of malacic cysts, with further reduction in density and size. Development of homolateral atrophy. The computer tomographic diagnosis of cerebral infarcts during Stage I is often very difficult. Distinction from infiltrating tumour is often possible only after further observation. The diagnosis of cerebral infarcts in stages II and III is possible in most cases. Haemorrhagic cerebral infarcts do not follow a temporal pattern as accurately as anaemic infarcts. They show circular increase in contrast of slowly diminishing size. The increased contrast persists considerably longer and is clearly distinguished from that in an anaemic cerebral infarct.

Adolescent↗
PubMed1979

Prognosis of prophylactic anticoagulant treatment in ischaemic stroke.

Two groups of patients who had a stroke, prolonged reversible ischaemic neurological deficit or transient ischaemic attacks were compared; one group was treated with anticoagulants (phenprocoumon) and a matched control group was treated with other substances. Results showed a similar survival rate in both groups, but significantly fewer recurrences were seen in the surviving patients treated with anticoagulants.

4-Hydroxycoumarins↗
PubMed1979

A correlation of clinical findings and CT in ischaemic cerebrovascular disease.

248 patients with an ischaemic stroke were investigated with computer tomography. A hypodense lesion was observed in 18% of TIAs, 76% of PRINDS and 95% of completed stroke patients. In the patients with TIA the hypodense lesions were mainly single ones, whereas completed stroke patients also had a significantly higher proportion of more bilateral lesions. Atrophy was present in 44% of TIA patients, 68% of PRIND patients and 82% of completed stroke patients. Atrophy was generalised in 60% of the patients and homolateral in only 16%. Contrast medium enhancement in a hypodense area occurred only in patients with PRIND and completed stroke and never in TIA aptients. Multiple lesions and atrophy were significantly more common in patients with dementia. The time course showed oedema initially in 47% of patients which fell to 25% after the 1st week. Contrast medium enhancement was present initially in 42% of the patients, rose to 70% until the 3rd week and then fell continuously until the 6th week. The change from an indistinct to a distinct outline of a lesion coincided with this.

Atrophy↗
PubMed1979

Measurement of regional cerebral blood volume using the EMI 1010 scanner.

Regional cerebral blood volume (rCBV) was measured in 14 patients with normal CT scans. An EMI CT 1010 scanner was used in combination with a computer subtraction technique. The mean CBV in the cortex was 5.0 ml/100 ml of tissue and 2.2 in the white matter. Regional differences were not significant and no difference was found between the right and left hemispheres.

Adolescent↗
PubMed1979

[The value of EEG and computertomography in ischemic stroke (author's transl)].

35 patients with ischaemic cerebrovascular disease were investigated using EEG and computertomography on the same day and the results from both investigations were compared. The EEG was pathological in 27 cases of which 26 showed focal changes and one case generalised changes. In 8 patients the EEG was normal. The CT-results showed a hypodense lesion in 17 patients and multiple hypodense lesions in 3 patients. 13 cases had atrophy and a normal CT was present in 2 cases. In 26 patients the EEG and CT results were both pathological and in one case both normal. In the diagnosis of ischaemic cerebrovascular disease both of these noninvasive investigative techniques complement each other; CT demonstrating the morphology of a lesion whilst EEG shows more functional changes in the brain.

Adult↗
PubMed1979

[The importance of computer tomography in the diagnosis of epilepsy (author's transl)].

208 patients with epilepsy were investigated by computertomography (Emi Scanner CT 1010 and CT 5005). In 173 patients with generalised epilepsy 87 had a normal scan, 51 revealed a definitive diagnosis and 37 showed generalised atrophy. Of the 35 patients with partial seizures a definitive diagnosis was possible in 22; representing a higher proportion than the group with generalised seizures. A definitive diagnosis from the CT Scan was significantly more common in both patients with generalised and partial seizures when pathological neurological findings were also present. Symptomatic epilepsy was only significantly commoner in Dementia patients with generalised seizures. A significantly higher proportion of patients over 30 years old demonstrated a symptomatic epilepsy than those under 30 years of age.

Adolescent↗
PubMed1978

[Clinical diagnosis of normal pressure hydrocephalus (author's transl)].

5 patients are described in which normal pressure hydrocephalus was diagnosed. The criteria on which the diagnosis was based were a cerebrospinal fluid perfusion test and an air study. Pathological verification was additionally obtained in 2 patients. The clinical picture in all patients was characterized by dementia. 4 patients were incontinent and 3 were paraspastic.

Adult↗
PubMed1978

Calculation of cerebral tissue and cerebrospinal fluid space volumes from computer tomograms.

The volumes of the cerebral tissue, and internal and external cerebrospinal fluid spaces were calculated from the computer tomograms of 28 patients. On the basis of their different absorption coefficients, cerebral tissue and CSF space were outlines and their volumes calculated by computer. The ratio of cerebral tissue volume to CSF space volume was expressed as an index. This correlated well with an objective grading of severity of hydrocephalus. The index in patients without pathology was between 10.5 and 18.4. In cerebral atrophy the index was between 2.1 and 6.7 depending upon the severity. In occlusive hydrocephalus it was between 1.0 and 5.6. The changes in the volume of the CSF space after treatment can easily by demonstrated by appropriate changes in the index.

Adult↗
PubMed1977

Relationship between disturbed rheological properties and cerebral hemodynamics in recent cerebral infarction.

In 75 patients with neurological symptoms due to RCI serum fibrinogen, whole blood viscosity and platelet aggregability have been determined before treatment was started. In addition, in 24 of the patients also HBF has been measured. In patients with RCI viscosity was significantly increased. Serum fibrinogen was higher at increased viscosity levels and when enhanced platelet aggregation was evident. At low shear rates increased blood viscosity correlated significantly with serum fibrinogen as well as with reduction of HBF.

Aged↗