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Biomedical subjects

G Koshi

Publications and source records attributed to G Koshi.

At least 55 records · Page 3Linked to original sources
PubMed1981

Brain abscess and other protean manifestations of actinomycosis.

Reports on human actinomycosis documented by culture have been infrequent, particularly from India. The present paper reports 12 cases of actinomycosis confirmed by culture. These include two unusual cases of actinomycosis of the brain with no granules in the pus, two pulmonary cases, one renal, one abdominal, and six cervico-facial. The lethal outcome with organ involvement, and the chronicity in some cases, warrant early etiologic confirmation and prompt treatment.

Actinomyces↗
PubMed1981

Rheumatic fever and rheumatic heart disease in rural South Indian children.

A preliminary pilot study of streptococcal infection and sequelae was initiated in 23 villages in 1973 using trained field workers for case detection. Part of the pilot programme, in 1974-75, involved 374 rural and 664 urban schoolchildren, and revealed that 14.9% of them had streptococcal pyoderma while pharyngitis was seen in 4.2%. The pilot study also revealed a high prevalence of rheumatic fever (RF) and rheumatic heart disease (RHD) in both rural (5.4/1000) and urban (6.0/1000) pupils. A long-term surveillance study was then undertaken in 3890 pupils attending 15 rural schools, from July 1975 to December 1978, when the prevalence of RF was found to be 0.5/1000 and of RHD, 4.4/1000, giving an overall rate of 4.9/1000. The incidence rate was found to be 1.7/1000 per year in 1976, 1.6/1000 per year in 1977, and 0 in 1978. The rate of compliance with primary prophylaxis was 90-100%, and with secondary prophylaxis was 92-93% of the 27 cases.

Adolescent↗
PubMed1980

Micro-indirect hemagglutination test for detection of antibodies to the Ibc protein of group B Streptococcus.

A micro-indirect hemagglutination test was developed for detecting antibody against the Ibc protein of group B Streptococcus. Formalin-preserved, tanned sheep erythrocytes were sensitized with a partially purified preparation of Ibc protein from a type Ic strain of group B streptococci. A total of 76% of 103 sera from pregnant and nonpregnant women had demonstrable antibody against this protein, with titers ranging from 10 to 320. Examination of five pairs of mother and cord sera revealed passive transfer of these antibiodies from mother to infant. This testing on a limited number of sera also revealed that elevated antibody titers against Ibc protein were more common among carriers of group B streptococci, especially those harboring strains with Ibc protein antigen, than among noncarriers. The technique described was found to be simple, specific, sensitive, and reproducible and may be of value in assessing the immune status of pregnant women as well as for epidemiological purposes.

Antibodies, Bacterial↗
PubMed1979

The reliability and rapidity of the coagglutination technic and its comparison with precipitin technic in the grouping of streptococci.

Three methods of the grouping of 170 strains of beta-hemolytic streptococci belonging to Groups A, B, C, F, and G by capillary and agar-gel precipitation using Lancefield extract and by coagglutination of antibody-coated protein A-containing staphylococci were compared. Capillary and agar-gel precipitin technics correctly grouped all 170 strains, with no cross-reaction. One hundred sixty-nine out of the 170 strains were also correctly grouped by the coagglutination technic, and the one strain with a cross-reaction was correctly grouped after blood--agar subculture. Although 20 of the 170 strains showed minor cross-reactions by the coagglutination technic, the specific groups were easily and unquestionably detected, and the minor cross-reactions were easily overcome. A rapid method of grouping by coagglutination technic using 4--6-hour broth culture, done on 75 strains, showed that 73 strains could be correctly grouped by the rapid method and two after overnight incubation. Thus, the coagglutination technic of grouping was found to be easy, reliable, and economical, and could be adopted in any routine diagnostic laboratory as a rapid grouping procedure.

Agglutination Tests↗
PubMed1979

Acremonium recifei as an agent of mycetoma in India.

Acremonium recifei was identified as the causal agent in a case of white grain eumycotic mycetoma of the hand which occurred in South India. The identification was based on the structure of the granules in tissue and on the morphological characteristics of the culture obtained from the granules. This case represents the first documented instance in which A. recifei has been found outside of Latin America.

Adult↗