Search PubMed⌕ Search

Biomedical subjects

G Koshi

Publications and source records attributed to G Koshi.

At least 37 records · Page 2Linked to original sources
PubMed1988

Corneal ulcer caused by Bipolaris hawaiiensis.

Following an injury to the right eye, a corneal ulcer with hypopyon developed in a leprosy patient. Direct examination of the corneal scrapings on three occasions showed septate, branched, dematiaceous hyphal elements. When scrapings were cultured on Sabouraud's glucose and brain heart infusion agars. Bipolaris hawaiiensis was isolated repeatedly. The patient responded successfully to treatment with nystatin ointment, although the central opacity of the cornea remained and visual acuity did not improve.

Corneal Injuries↗
PubMed1987

Development of a coagglutination (COA) technic to detect Candida antigenemia. I. COA versus Candida isolation.

A coagglutination (COA) test to detect Candida antigenemia was developed using locally produced Candida antiserum and COA reagent. All 68 controls had normal results. Two patient groups were included in this study. In Group 1, consisting of eight patients, with definite systemic or deep candidiasis proved by repeat Candida isolation, COA detected antigenemia in 100% as against 50% by counterimmunoelectrophoresis (CIE). In Group 2, 9 of 19 patients had respiratory infection; 4 patients revealed antigenemia by COA, 2 of whom had no Candida isolation. In these 2 patients therapy was initiated based on COA results. Of another nine patients with hematologic and malignant diseases, five (56%) revealed antigenemia by COA, three of whom had no Candida isolation; two died and one was discharged against advice. Transient antigenemia was detected by COA in a single patient with ulcerative colitis with Candida isolation. Thus, the COA test was found to be rapid, sensitive, and specific for the detection of Candida antigenemia. Furthermore, it had early diagnostic (seven days) as well as prognostic value, as revealed by response to therapy and decrease in COA titer. Being highly cost effective, this test is recommended as a simple test within the reach of any routine diagnostic laboratory.

Adult↗
PubMed1987

Nasal phaeohyphomycosis caused by Bipolaris hawaiiensis.

A bilateral nasal phaeohyphomycotic infection caused by Bipolaris hawaiiensis in an immunocompromised woman from India is described. Repeated direct microscopic examinations of the nasal scrapings revealed the presence of septate, branched, pigmented hyphal fragments intermingled with cells that divided internally by one transverse septum and a few cells that were chestnut brown dividing internally by septa in different planes to become muriform. Cultures of the scrapings yielded B. hawaiiensis. Local excision of the crusted lesion followed by application of 0.03% nystatin solution four times a day for 3 weeks cured the infection.

Female↗
PubMed1986

Trimethoprim resistance amongst urinary pathogens in south India.

Two hundred and eighty four strains of Enterobacteriaceae, responsible for significant bacteriuria, were isolated, over a three month period, in Vellore, India. Sixty-four per cent of these strains were resistant to 10 mg/l of trimethoprim. Moreover, this population was dominated by high level resistance (minimum inhibitory concentration greater than 1000 mg/l) and these accounted for 57.3% of all strains studied. Over half of the resistant strains were able to transfer trimethoprim resistance to standard Escherichia coli strains. However, the high incidence of transferable resistance did not result from the spread of one plasmid type as 58 different plasmid types were identified. These results are in marked contrast to recent findings in Europe where the incidence of high level transferable trimethoprim resistance is falling.

Ampicillin↗
PubMed1986

Unusual expression of new low-level-trimethoprim-resistance plasmids.

In a survey, 42% of trimethoprim-resistant clinical members of the family Enterobacteriaceae were able to transfer trimethoprim resistance to standard Escherichia coli strains when selection was made on complex bacteriological media. When transfer experiments were performed with minimal medium, another 16% of the clinical strains were shown to have transferred trimethoprim resistance. Twelve transconjugants produced negligible trimethoprim resistance in complex media but were resistant in minimal medium. The methionine, glycine, and purine components of complex media appeared to be responsible for the reduced expression of trimethoprim resistance in these strains.

Conjugation, Genetic↗
PubMed1985

Changes in incidence of shigella subgroups and their antibiotic susceptibility pattern in Vellore, South India.

Investigations were carried out on faecal samples of cases of diarrhoea presenting at a hospital in Vellore, South India, over a period of 1 year. Pathogens were identified and tested for susceptibility to a number of antibiotics. Blood cultures were carried out where septicaemia was suspected. It was found that the relative frequencies of the shigella subgroups have changed since previous reports. The paper reports changing resistance patterns of shigellae to antibiotics and the existence of a number of multiple drug resistant strains. The authors recommend constant surveillance of resistance patterns so that effective therapy can be given in emergency conditions.

Drug Resistance, Microbial↗
PubMed1983

Streptococcal antibodies and complement components in tropical post-streptococcal glomerulonephritis.

Anti-deoxyribonuclease "B' was elevated in 94.9% of 59 cases of post-streptococcal glomerulonephritis studied, whereas ASO was elevated only in 54.4% of cases showing that the ADNB titre is a more sensitive indicator of antecedent streptococcal infection than ASO, in tropical countries with a high prevalence of pyoderma. Serum C3c (beta 1A) levels were significantly decreased, especially in the early phase of the illness and returned to normal with remission. C4 levels were decreased only in the early phase of the illness, suggesting involvement of the alternate pathway subsequent to classical pathway activation.

Adolescent↗
PubMed1983

Immune response to Bacteroides ureolyticus in a patient with brain abscess.

A high titer (1:256) of agglutinating antibodies against Bacteroides ureolyticus was demonstrated in a 35-year-old woman with brain abscess, using a microagglutination test. Tests done with B. ureolyticus and heterologous sera as well as with heterologous strains and the patient's serum were negative. Circulating antibody to B. ureolyticus has not been reported previously.

Adult↗