Biosynthesis of purple membrane: control of retinal synthesis by bacterio-opsin.
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Biomedical subjects
Publications and source records attributed to G Herrmann.
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It was shown that reduction in exercise capacity because of latent heart insufficiency could be significantly demonstrated by the so-called pre-ejection index PI, measured under conditions of rest. On the other hand, normals did not show any significant interrelation between PI and parameters related to exercise capacity, obtained by spiroergometric measurements. The pre-ejection index PI is a non-invasive parameter which compares the pre-ejection period in upright and supine posture. Since spiroergometric measurements could not be made under vita-maxima conditions, PI values were compared with parameters of submaximal exercise. Exercise was performed on the bicycle ergometer, with oxygen consumption and heart rate being recorded. Measuring results also revealed that by means of the pre-ejection index the necessity and effectiveness of glycoside medication may be objectively defined. Measuring techniques are described and statistically processed data are presented.
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114 patients with permanent colostomy for carcinoma of the rectum were compared by questionnaire and interview with 110 cancer patients, having undergone colonic resection but not bearing a colostomy. The patients' own assessment of their health was for the colostomy group even better than for the controls. The emotional state before and after surgery showed significant degrees of hopelessness, depressions and fear especially for young women awaiting colostomy. Social contacts were considered as far as visits of friends or cinema, theatre are concerned. Sexual activity decreased significantly for 75% of colostomized men. In 40% organic lesions led to impotence. The Giessen test revealed significant rates of social impotence, negative social resonance and depression for men with colostoma.
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There was no difference between ethrane and halothane in respect of anaesthetic technique, except that on account of its physico-chemical properties induction and recovery was quicker with ethrane. Anaesthesia with this agent is, therefore, more easily controlled. Induction in children was rapid and non-irritating. The marked muscle relaxing effects of the drug carry some risk of impaired gaseous exchange in the spontaneously breathing patient. At higher concentrations ethrane, like all inhalation anaesthetics, is liable to cause respiratory depression. The cardiovascular system remained remarkably unaffected provided induction was slow, i.e. the concentration of ethrane was not too suddenly raised. The blood chemistry appeared to be unaffected, but the electroencephalogram showed certain changes the clinical significance of which has so far not been established.
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