Biomedical subjects

G H Collins

Publications and source records attributed to G H Collins.

At least 109 records · Page 6Linked to original sources

PubMed1976

Meningiomas causing spontaneous intracranial hematomas.

Four cases of spontaneous intracranial hematomas caused by unsuspected meningiomas are reported. Nine previous cases were found in the literature and the entire series of 13 cases is reviewed. Because of their unusual clinical presentation, these cases were not diagnosed correctly prior to radiological studies. Hypertension, trauma, and blood dyscrasia played no significant pathogenetic role. The histological features of these hemorrhagic meningiomas are described, and the importance of adequate radiological investigations and early radical surgery is stressed.

Aged↗

PubMed1974

Feline hereditary neuroaxonal dystrophy.

A newly recognized neurologic disorder of cats is described. It is characterized clinically by an abnormal coat color and development of progressive ataxia during infancy. Breeding experiments indicate that the disease is inherited in an autosomal recessive manner. Pathologically, neurologic lesions closely resemble those described in infantile neuroaxonal dystrophy of children. The most prominent microscopic alterations were marked ballooning of nerve cell processes within specific regions of the brain stem and atrophy of the cerebellar vermis. Ultrastructural studies demonstrated that dystrophic axons contained electron-dense flocculent material, multilaminated membrane-bound osmiophilic bodies and filaments. Examination of the inner ears revealed depletion of neurons in the spiral ganglia and homogeneous eosinophilic bodies within the spiral ganglia, nerve fiber tracts and organ of Corti. The concept that the disease represents an inborn error of metabolism was supported by finding axonal dystrophy in neonates prior to development of cerebellar atrophy or recognition of clinical symptoms.

Animals↗

PubMed1973