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Biomedical subjects

G H Collins

Publications and source records attributed to G H Collins.

At least 91 records · Page 5Linked to original sources
PubMed1981

Familial dementia of adult onset with pathological findings of a 'non-specific' nature.

A family is described in which 4 of 10 siblings developed a dementing illness that culminated in death within five to six years of onset. The pathological findings in 3 members were strikingly similar, and consisted of widespread nerve cell loss and astrocytosis within the cerebral cortex, status spongiosus within the outer cortical layers and, in 2, nerve cell loss and astrocytosis within the dorsomedial nucleus of the thalamus. It is concluded that the disorder described in this report does not conform precisely to any of the currently recognized categories of familial dementing disease.

Aged↗
PubMed1981

Pallidonigral pigmentation and spheroid formation with multiple striatal lacunar infarcts.

A 72-year-old hypertensive man had focal seizures and mild memory loss. At autopsy, there were many lacunar infarcts, particularly in the neostriatum. Rust-brown discoloration and spheroid formation within the globus pallidus and pars reticulata of the substantia nigra resembled Hallervorden-Spatz disease, in which more detailed analysis of the striatum may be worthwhile.

Aged↗
PubMed1980

Chorea gravidarum. Report of a fatal case with neuropathological observations.

In a 23-year-old primigravida with no prior history of rheumatic fever, choreiform movements developed late in the third trimester, and she died in a state of hyperthermia 14 days later. Results of neuropathological examination showed, as the basis for the chorea, nerve cell loss and astrocytosis within the striatum (especially the caudate nucleus). Anaylsis of the case in conjunction with a review of the literature strongly suggests that chorea gravidarum should be regarded as a syndrome rather than a specific disease entity.

Astrocytes↗
PubMed1980

Heat stroke. Report of three fatal cases with emphasis on findings in skeletal muscle.

Three fatal cases of heat stroke were encountered in the central New York area over a two-month period. Although in each instance one or more predisposing factors were identified, exertion clearly played a role in its development in only one case. In addition to laboratory and postmortem findings indicative of dysfunction of many organ systems, there was morphological evidence of widespread damage to skeletal muscle.

Adult↗
PubMed1979

Pathology of an arachnoid cyst. Case report.

Accidental death brought to autopsy a 19-year-old girl with asymptomatic arachnoid cyst which had expanded from the region of the interpeduncular cistern so as to replace the third ventricle and extend into both alteral ventricles. Associated with this expansion was a significant degree of hydrocephalus, compression of the walls of the lateral ventricle, and obliteration of the normal structures of the floor of the third ventricle. The histological structure of the cyst wall and its relationship to the normal arachnoid are defined and found to consist of a reduplication of the normal arachnoid membrane resulting in a space within the arachnoid tissue. It is suspected but not proven that the cyst was congenital, resulting from an abnormality in development. Some suggestions are offered regarding the mechanism for its enlargement.

Adolescent↗