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Biomedical subjects

G Gruber

Publications and source records attributed to G Gruber.

At least 109 records · Page 6Linked to original sources
PubMed1981

[Arterial hypertension in university students].

Experiences of a hypertension dispensary during student consulting hours are reported. The dispensary was built up with 106 students who were classified by a screening from a larger group at the beginning of an academic year. It comprised 2 groups which underwent different therapeutic measures, borderline value hypertensives (n = 53) of a general medical therapy, hypertensives in clinical degree of severity I (n = 53) of a medicamentous therapy, i.e. a propranolol medication. After 2 years, medical as well as pedagogical and political problems of higher education were analysed. For particular phases of stress, as there are during study, general measures alone are not estimated as effective therapy in borderline value hypertensives, though several risk factors could be influenced favourably. So the number of smokers decreased from 28 to 7%. The blood pressure values showed a normalisation only in 10.5%, in 55.5% a borderline value area and in 34% an increasing tendency. On the other hand, in all hypertensives under propranolol medication, a clear decrease in blood pressure could be achieved. It is to be recommended that antihypertensive drugs be used in borderline value hypertensives in particular stress situations.

Adolescent↗
PubMed1981

[Circulatory regulation during orthostatic test in young hypertensive patients].

The recognition of orthostatic circulatory dysregulations the usual circulation test were critically analysed concerning their valency. The results of our examinations show that all tests are only a supplementing diagnostics to the comprehensive directed anamnesis and clinical examination. The importance of the orthostasis in the therapy of hypertension is known. Taking into consideration the complex approach, the frequency of orthostatic circulatory dysregulations is also evident in untreated juvenile hypertensive patients. Juvenile hypertensive patients with orthasthenia should be treated with a basis therapy with beta-receptor blockers.

Adult↗
PubMed1981

[Heart rate and blood pressure under psychological and physical laboratory stress in young hypertensive patients following long-term therapy with the beta receptor blocker propranolol].

16 male hypertensive patients who could be compared according to the behaviour of blood pressure and the heart frequency in the psychophysiological experiment, according to age the characteristic signs of the profession underwent a long-term therapy with propranolol. After an average duration of the therapy of 31 months the patients were exposed to psychical and physical laboratory loads after a three-week interval in therapy. The behaviour of the blood pressure and of the heart frequency under psychical and physical laboratory loads before and after the therapy with propranolol are compared.

Adult↗
PubMed1980

[Hypertensive regulatory disorders in adolescents after a 10-year therapy-free interval].

After a 10 years' interval 89 of 212 patients with a hypertensive disturbance of the regulation could again be examined. Of the 89 patients only 6 were in dispensary care due to high blood pressure; of the 83 patients who are not in dispensary care 30 showed a normal blood pressure and 18 a hypertension. The factors of influence hereditary disposition, overweight, neurotic personality structure and disturbances of lipometabolism increase in their frequency from normotonics over borderline patients to hypertensives. It is referred to practical consequences.

Adolescent↗
PubMed1980

[Digoxin therapy in the aged under serum level control with special reference to hypertension].

In 125 patients with hypertension in the clinical degree of severity II despite normal concentrations of creatinine and potassium in the serum at the age of more than 65 years significantly higher digoxin serum concentrations of 2.36 +/- 1.19 nmol/l (= 1.84 +/- 0.93 ng/ml) and intoxications than in younger patients with 1.45 +/- 0.55 nmol/l (= 1.13 +/- 0.43 ng/ml) were found. After discussion of the results of other investigators comes the recommendation in patients at an older age (beginning with about 65 years) and in renal insufficiency to apply digitoxin instead of digoxin, taking into consideration the mean maintenance dose of 0.1 mg/die.

Adult↗
PubMed1979

[Comparative studies in young hypertensive patients at rest and after standardized physical and sensomotoric exertion].

The acknowledged role of central-nervous mechanisms in the etiopathogenesis of the essential arterial hypertension led to the use of a psycho-physiologic test method with the aim of the early recognition of stress-induced permanent changes of physiologic functions. We succeed in proving the chosen sensumotoric stress in a group of patients with essential arterial hypertension which at first appears uniform in clinical respect allows a further differentiation. On the basis of the behaviour of defined physiologic and biochemical parameters after physical and sensumotoric stress it is referred to the necessity of a differentiated therapy of the early form of the essential arterial hypertension.

Adult↗
PubMed1979

[Radioimmunologic determination of serum digoxin. Methodological and 1st clinical experiences].

The tested quality signs of the digoxin-RIA (Medica) correspond to other RIA-test methods. The digoxin-RIA (Medica) is, therefore, well suited for clinical examinations. In the dilanacin- (digoxin-) long-term therapy with the maintenance dose of 0.5 mg digoxin a day 75.4% of the patients examined (n = 65) were within the therapeutic field. In each case 12.3% were underdigitalised or overdigitalised, respectively. In the 8 patients in the toxic region only the half showed signs of digoxin intoxication. It is referred to the importance of creatinine and potassium in the serum, the digoxin clearance depending on age, the body weight and the body surface, respectively, in very obese patients for the height of the serum digoxin level and for the compatibility of this heart glycoside.

Aged↗
PubMed1977

[Comparison of the effects of pipothiazine palmitate and fluphenazine decanoate. Results of a multicenter double-blind trial].

Fluphenazine decanoate and pipothiazine palmitate were compared concerning their effect and side-effects. 61 schizophrenic patients were treated up to 6 months in a multicenter double-blind trial. Assessments were made on day 0 and after 5, 10, 17 and 22 weeks of treatment using the AMP system. Pipothiazine palmitate was injected every 4th week and fluphenazine decanoate every 3rd week. The most often applied dosage was 100 mg pipothiazine palmitate and 25 or 37.5 mg fluphenazine decanoate. Data analysis of the AMP system at the symptom level showed the better antipsychotic effect of pipothiazine palmitate. A comparison between the two groups by means of analysis of covariance at the syndrome level showed no statistical significant differences between the effects of fluphenazine decanoate and pipothiazine palmitate.

Antipsychotic Agents↗
PubMed1976

[Diagnosis of coronary insufficiency using bicycle ergometry].

The bicycle ergometry has proved as screening test for the diagnostics of the latent coronary insufficiency. Taking into consideration well-known prerequisites, indications, contraindications, the criteria of withdrawal and the ECG criteria in coronary insufficiency own results and experiences from an analysis of 1,000 bicycle ergometries are presented and compared with literary data.

Adult↗