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Biomedical subjects

G Galvan

Publications and source records attributed to G Galvan.

At least 73 records · Page 4Linked to original sources
PubMed1977

[Emptying of goitre cysts by small-needle aspiration (author's transl)].

Small-needle aspiration was practised up to 16 times (average 2.7 times) in 89 patients with cystic thyroid nodules. Re-examination 7 days to 22 months later showed that the nodule had disappeared or the amount of cystic fluid had decreased to 30% or less in 32 patients. All patients also received suppressive doses of thyroid hormones. It is suggested that additional injection of sclerosing fluid into the cyst may improve results further.

Biopsy, Needle↗
PubMed1977

[Fine needle biopsy of cold goiter nodules (author's transl)].

Fine needle biopsy of hypofunctional, scintigraphically detected cold goiter nodules is being increasingly applied as a diagnostic method. Its diagnostic value is estimated by the results gained from 4,555 punctured patients, 1,076 of these nodules were histologically proven, and from the literature. The most important indication for the application of this method is a neoplastic lesion of the thyroid. 6.8% of 20,384 nodules were cytologically suspicious or malignant. Of 2,412 surgically controlled patients 85.5% were correctly diagnosed. Among 490 malignancies 92.1% were correctly diagnosed and 7.9% were false negatives.

Biopsy, Needle↗
PubMed1977

[Biochemical data in the fluids of cystic degenerated euthyroid goiters (author's transl)].

Examinations of sera and cyst fluids in patients with cystic degenerated euthyroid goiters showed significant differences between the values of the cyst fluids and sera for almost all of the chemical substances. In the brown cyst fluids there are mostly higher values compared with the appropriate sera. Autolysis, diffusion and resorption, metabolic changes and, in the case of thyroid hormones, active incretion by wall-forming thyroid tissue, are the reasons for these differences in the concentrations.

Blood Chemical Analysis↗
PubMed1976

[Employment of electronic data processing in an outpatient department for diseases of the thyroid (author's transl)].

A report is made on the model of a programmed outpatient department for diseases of the thyroid, which proved its value since 1973. Permanent patient data, diagnoses, therapy, course of therapy, suggested therapy, recommended examinations, follow-up dates and laboratory findings are recorded on punch cards. With the aid of a data processing center, medical reports are issued and settlements passed to account. The entire data put out are available for documentation purposes and statistical evaluations.

Ambulatory Care↗
PubMed1976

[Fine needle biopsy of "cold" struma nodules in 4555 patients of an endemic goiter area. Results and clinical significance].

Over a period of 8 years, thin needle biopsies of hypofunctional, scintigraphically cold goiter nodules were performed in 4555 patients. 1076 underwent surgery and cytological diagnoses were thereby histologically confirmed. In 715 patients with normal or degenerative cytological findings, the diagnosis was correct in 95.1%. On the other hand, 8 malignancies, 13 Hürthle-cell adenomas, and 26 cases of Hashimoto's thyroiditis were misdiagnosed. The 8 diagnostic errors in the malignancies were due to puncturing of the wrong nodule in 3 cases and, in 5 cases, due to highly differentiated, partially degenerated, follicular carcinomas. In 322 cases with suspect or malignant cytological findings, 129 malignancies (40%) were confirmed. In most cases, false positive diagnosis was due to histologically atypical adenomas, e.g. Hürthle-cell adenomas. Hashimoto's thryoiditis could be readily diagnosed only in the advanced stage. The clinical diagnosis of de Quervain's thyroiditis can be verified by cytological examination.

Biopsy, Needle↗
PubMed1976

[Cystic degeneration of autonomous adenomas (author's transl)].

Follow-up examinations in four patients with autonomous adenomas showed cystic degeneration in the autonomous adenomas 20 to 45 months after the first examination, confirmed by fine needle biopsy. Clinical improvement occurred three times with scintigraphic compensation, decompensation occurred once without clinical deterioration. In particular cases a therapeutic policy of wait and see is justified in patients with autonomous adenomas because they may remain clinically inconspicuous for a long time; on the other hand there is a possibility of a cystic degeneration.

Adenoma↗