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Biomedical subjects

G Fujii

Publications and source records attributed to G Fujii.

At least 73 records · Page 4Linked to original sources
PubMed1976

Immunologic and chemical studies on mucopolysaccharide derived from murine lymphosarcoma.

Mucopolysaccharide was prepared from media in which the Gardner's lymphosarcoma cells were cultured. Multiple intraperitoneal injections of the preparation into syngeneic mice resulted in enhancement of the tumors which were inoculated prior to the injections. Sera of these hosts contained antibodies reacting with antigens of the outer layer of the tumor cells. Chemical analyses of the preparation showed that the mucopolysaccharide is composed of hexosamine, uronic, acid, hexose, and proteins. The mucopolysaccharide was shown to possess unique migration rate on electrophoresis and thin layer chromatography.

Animals↗
PubMed1975

Inhibitory effect of progesterone on the phytohaemagglutinin- induced transformation of human peripheral lymphocytes.

Effect of sex steroids, progesterone and estradiol-17beta, on transformation of human lymphocytes induced by PHA was investigated. Responses of peripheral lymphocytes from non-pregnant women to PHA was markedly reduced in the presence of progesterone at a concentration of 10(3) or 10(4) ng/ml. Estradiol-17beta, on the other hand, had no effects on the PHA-induced transformation under the present experimental conditions. The immunosuppressive property of progesterone may contribute to depression of maternal cell-mediated immunity against fetus during pregnancy.

Drug Interactions↗