Search PubMed⌕ Search

Biomedical subjects

G Favez

Publications and source records attributed to G Favez.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Changes in the hemodynamics of the lung and the right ventricle during rest and exertion in 2 groups of patients with chronic broncho-obstructive syndrome of different severity].

Forty patients with chronic obstructive pulmonary disease (COPD) underwent right heart and central catheterization at rest and during exercise when not in a state of acute exacerbation. They were divided into 2 groups of different functional gravity: group I: FEV1 less than or equal to 1250 ml, RV/TLC greater than or equal to 55% (24 patients); group II: FEV1 > 1250 ml, RV/TLC < 55% (16 patients). At rest, group I had mean pulmonary artery pressure, pulmonary arteriolar resistance, and arterial PCO2 significantly higher, and arterial PO2 significantly lower, than group II. There was no difference in cardiac index, mean atrial pressure and pulmonary wedge pressure between the two groups. During exercise, mean right atrial and pulmonary wedge pressure increased markedly in group I and showed a significant difference from the values of group II. For pooled data of groups I and II, there was a correlation between FEV1 and mean right atrial pressure under exercise and between arterial PO2 and right atrial pressure under exercise. It is concluded that (1) subdividing patients with COPD, as reported here, determines two different blood gases and pulmonary hemodynamic subsets when taken at rest; (2) during exercise, group I patients have "abnormal" right and left ventricular function; (3) FEV1 and arterial PO2 on physical exertion serves to predict mean right atrial pressure under exercise.

Blood Pressure↗
PubMed1980

[Persistence of hypoxemia after complete reexpansion of the lung in patients with idiopathic spontaneous pneumothorax].

Oxygen arterial partial pressure (PaO2) has been measured in 38 patients with idiopathic spontaneous pneumothorax (ISP) and in 20 of them 8-9 days after full expansion of the lung within 1-3 days by aspiration through chest tube drain. The PaO2 was initially 69.0 +/- 9.6 Torr (predicted value 99.6 +/- 6.6 Torr, p < 0.01) and the alveolo-arterial O2 pressure (AaDO2) difference was 28.2 +/- 8.9 Torr (pred. val. 8.6 +/- 2.5 Torr, p < 0.05). PaO2 in complete ISP (25 cases) was 65.6 +/- 6.9 Torr and in incomplete ISP 74.3 +/- 11.1 Torr (p < 0.01). PaO2 difference between initial values (64.6 +/- 7.4 Torr) and after full expansion of the lung (77.6 +/- 10.0 Torr), as measured in 20 cases and AaDO2 difference (27.5 +/- 9.8 Torr and 15.33 +/- 10.5 Torr), were statistically significant with p < 0.01). The hypoxemia still observed after full expansion of the lung may be explained by the persistent small airway closure possibly due to increased surface tension and the subsequent transsudation still present in some peripheral air spaces.

Adolescent↗
PubMed1979

[Retrospective study of 50 cases of idiopathic fibrosing alveolitis with catamnesis].

44 out of 50 patients with idiopathic fibrosing alveolitis were followed up from 1 month to 11 years (mean 2 years 9 months). One patient out of 13 (8%) with 4 symptoms or fewer (mean follow-up 55 months) died. 23 out of 31 (74%) with 5 symptoms or more (mean follow-up 24.3 months) died, and 68% of fatalities occurred within 2 years. Lung function tests were performed in 47 cases and histological diagnosis in 38. Correlations between symptoms, lung function, and roentgenological and histological patterns are discussed. Two circumstances dramatically increased lethality: occurrence of 5 symptoms or more in a period of less than 2 years.

Adult↗
PubMed1979

[Correlations between hemodynamic measures and respiratory functions in patients with chronic obstructive lung syndromes].

Fourteen patients with chronic obstructive pulmonary disease underwent right catheterization with a Swan-Ganz catheter to correlate lung function with hemodynamic features at rest and on exercise. There appears to be a good correlation between some pulmonary function tests (FEV1, RV/TLC, PaO2 at rest and on exercise) and mean pulmonary artery pressure at rest and on exercise in these patients.

Blood Pressure↗
PubMed1978

[Clinical and radiological diagnosis of chronic obstructive lung syndromes].

The clinical signs produced by the respiratory movements reveal the main patho-physiological types in patients with chronic obstructive lung disease. Roentgenological signs do not correlate with the severity of ventilatory disorders and pre-capillary hypertension. Conversely the roentgenological signs of the post-capillalry hypertension are precocious and reliable.

Aged↗
PubMed1978

[Fatal outcome of emphysema without increased bronchial resistance and 6 cases of chronic dyspneic hypoxemic bronchial disease with normal spirometry].

The cases of seven patients with dyspnea, hypoxemia and normal ventilatory tests are presented. Closing volume was measured in 6 and was increased. Two were heavy smokers, 2 were obese, and 2 were exposed to inhalation of industrial irritants. The last patient had severe dyspnea and pronounced hypoxemia which eventually resulted in pulmonary hypertension and right ventricular failure. Lung scan was normal. Plethysmography showed normal bronchial resistance. Autopsy revealed chronic bronchitis, bronchiolectasis and emphysema. This case was interpreted as an example of fatal outcome of small airway disease.

Adult↗
PubMed1977

[Increased closing volume in asymptomatic respiratory sarcoidosis].

In 21 patients with asymptomatic respiratory sarcoidosis, 11 with hilar lymph node enlargement (stage I) and 10 with both hilar and lung involvement (stage II), pulmonary function tests revealed that the closing volume was increased as compared with control values obtained from healthy individuals of the same age and smoking habits. The difference was statistically significant but more pronounced in stage II patients than in stage I patients. Other function tests were normal (VC, FEV1, MMF, RV, TLC, DLCOSB).

Adult↗
PubMed1977

[A case of broncho-pulmonary aspergillosis developing for 24 years].

A case of allergic broncho-pulmonary aspergillosis has been diagnosed on the basis of recurrent, transient pulmonary infiltrates, serum precipitins against Aspergillus fumigatus and a dual-type reaction to intradermic testing with aspergillus antigen. Despite a prolonged course (24 years), lung function tests do not show changes.

Antibodies, Fungal↗
PubMed1977

[Atelectasis without bronchial obstruction].

Five patients with acute pneumonia and transitory atelectasis without bronchial obstruction are presented. The reduced lung volume in these cases, in a case of shock lung, together with a similar phenomenon in pulmonary embolism, is tentatively related to a possible disorder of the surfactant system.

Adolescent↗
PubMed1976

[Early diagnosis of bronchial cancer: its usefulness].

Incidence of and mortality from bronchial carcinoma are reviewed. The advantages of early recognition of the disease and the favourable role of early recognition as a factor in the therapeutic outcome are stressed. Etiologic factors and diagnostic procedures are summarized. The need for a public education program is emphasized.

Bronchial Neoplasms↗