Search PubMed⌕ Search

Biomedical subjects

G F Marx

Publications and source records attributed to G F Marx.

At least 91 records · Page 5Linked to original sources
PubMed1978

Neonatal neurobehavioral tests following cesarean section under general and spinal anesthesia.

The Scanlon Group of Early Neonatal Neurobehavioral Tests (E.N.N.S.) was administered to 150 babies delivered by elective cesarean section. Fifty of the mothers were induced into general anesthesia with thiopental, 4 mg. per kilogram, and 50 with ketamine, 1 mg. per kilogram. Fifty mothers received spinal anesthesia with 6 to 8 mg. of tetracaine. All mothers receiving spinal anesthesia were given 100 per cent oxygen by a transparent face mask and all undergoing general anesthesia received N2O-O2 (6L:6L) until delivery of the baby. All mothers were healthy and all babies weighed 2,500 grams or more, were apparently normal, and had Apgar scores of 7 or more at one minute to 10 at five minutes. Spinal anesthesia was associated with the greatest percentage of high scores on both the first and second day for overall assessment, pinprick response, tone, rooting, sucking. Moro response, placing, alertness, and total decrement (habituation) scores. There was a statistically significant difference between all the scores for spinal compared to the other two groups. The scores were lowest following a thiopental induction and intermediate with ketamine although the difference did not reach statistical significance.

Adolescent↗
PubMed1978

Postpartum uterine pressures under halothane or enflurance anesthesia.

Postpartum uterine pressures were measured in healthy women with an intrauterine microballoon before, during, and after administration of different concentrations of halothane or enflurane. Arterial blood samples for anesthetic levels were obtained at intervals. Frequency and intensity of contractions diminished markedly when blood levels exceeded the equivalent of 1/2 MAC (minimum alveolar anesthetic concentration which produces immobility in one-half of subjects exposed to a noxious stimulus) of nonpregnant adults, but normal patterns returned promptly on lightening of anesthesia. Response to 10 mU of oxytocin was suppressed at blood levels corresponding to between 3/4 and 1 MAC of the agents. Halothane and enflurane exert equipotent dose-related reversible effects on the activity of the full-term pregnant human uterus.

Anesthesia, Inhalation↗
PubMed1978

Neonatal neurobehavior in the first 48 hours of life: effect of the administration of meperidine with and without naloxone in the mother.

The early neonatal neurobehavioral scale was administered to three groups of newborns at 2, 4, and 24 hours of age. Group 1 consisted of 28 babies whose mothers had received no narcotics during labor, group 2 of 33 babies whose mothers had received meperidine hydrochloride alone during labor, and group 3 of 40 babies whose mothers had received meperidine followed by 0.4 mg of naloxone hydrochloride intravenously approximately 15 minutes before delivery. Babies who were not exposed to meperidine showed a statistically significantly greater percentage of high scores than those exposed to meperidine alone for all items on the neurobehavioral scale at 2 and 4 hours and for all items except tone and Moro response at 24 hours. Similarly, babies whose mothers had received meperidine and naloxone showed a significantly greater percentage of high scores than those whose mothers had received meperidine alone at 2 hours of age. At 4 hours a difference was found for tone and rooting and at 24 hours for overall score, placing, and total decrement score. It is concluded that naloxone given intravenously to the mother reverses the effect of meperidine on neonatal neurobehavior for approximately two hours after birth. At 4 and 24 hours, however, the neurobehavior of neonates exposed to meperidine and naloxone is depressed almost as much as that of babies exposed to meperidine alone.

Child Behavior↗
PubMed1978

[Anaesthesia for cesarean section in a patient with acute viral hepatitis (author's transl)].

Acute viral hepatitis is hazardous in the obstetric patient because of associated multi-system involvement which may include coagulation defects. The fetus may be compromised by maternal complications as well as by high levels of indirect bilirubin which crosses the placenta. Cesarean section is frequently indicated for fetal distress or failed progress of labor. An elderly primigravida with severe acute viral hepatitis complicated by gastrointestinal bleeding, hypofibrinogenemia, thrombocytopenia and prolonged prothrombin and partial thromboplastin times required emergency cesarean section. Clotting factors were replenished prior to surgery. General anesthesia with low-dose ketamine induction and high inspired oxygen fraction was considered the method of choice for the specific maternal and fetal problems.

Adult↗
PubMed1977

Correlation of biochemical data with Apgar scores at birth and at one minute.

A prospective study of 66 unselected neonates revealed a better correlation of umbilical artery blood biochemical data with the Apgar score at birth compared with the score at 1 min. The data confirmed also that inclusion of the score for "colour" detracts from the value of the total score. An Apgar score at birth is more valuable than the score at 1 min.

Apgar Score↗
PubMed1976

Tracheobronchial epithelial multinucleation in preeclampsia.

Smears were made from the tracheobronchial washings from 40 parturient women undergoing operative delivery while under general anesthesia administered via an endotracheal tube. There was a significantly greater incidence of epithelial multinucleation in the smears from 12 patients who had had preeclampsia for more than 24 hours than in those from 13 healthy pregnant women, from eight women with preeclampsia of less than 24 hours' duration, and from seven women with associated diseases other than preeclampsia. Although we are unable to explain this phenomenon, we have reviewed its possible causation in the face of existing theories on the cause of preeclampsia.

Bronchi↗
PubMed1976

Neonatal blood pressures.

Arterial blood pressures were taken by the Doppler ultrasound method in 134 unselected mature neonates (birthweights 2,600-3,900 grams) who were managed in the same manner after birth. Blood pressures were measured at 3-5, 10 and 30 minutes of life and, if indicated, intermittently during the next 24-48 h. Left and right arm pressures were identical or differed by only 1-2 mm Hg. Lower than normal blood pressures were found in 4 groups of infants: those born by cesarean section, those recovering from intrauterine asphyxia, those exposed to maternal anti-hypertensive therapy, and those whose mothers received thiopental within four minutes of delivery. Return of the low pressures to within the normal range was fastest following thiopental induction in the absence of fetal asphyxia and slowest after antihypertensive therapy.

Antihypertensive Agents↗
PubMed1975

Chloroprocaine-bupivacaine sequence for obstetric extradural analgesia.

Two case reports, one a vaginal delivery, the other a Caesarean Section, have been presented to demonstrate the rationale of employing a chloroprocaine-bupivacaine sequence for extradural analgesia in obstetrics. Use of chloroprocaine for initiation and bupivacaine for maintenance of the block offers at least three advantages: (1) onset of pain relief is prompt while duration is prolonged; (2) more than one "test" dose of chloroprocaine may be employed with safety in rapid succession; (3) two drugs with different metabolic patterns are used, each in reduced amount.

Anesthesia, Epidural↗
PubMed1975

Tympanic temperature during labour and parturition.

Tympanic temperature was monitored during labour and delivery in six primigravidae and five multigravidae. Temperature increased temporarily with each contraction and progressively during the course of labour. The increases, which were greater in primiparae than in multiparae (mean cumulative increase 1.46 degrees C and 0.51 degress C respectively), reflect the metabolic expenditures associated with contraction of uterine and skeletal muscles.

Body Temperature↗
PubMed1975

Successful management of severe aortocaval compression in twin pregnancy.

In a patient with severe aortocaval compression, simultaneous brachial and femoral blood pressure measurements demonstrated the need for a 30 degrees left-down tilt to avoid significant obstruction of the vessels. When emergency cesarean section became necessary, proper positioning of the patient was readily accomplished.

Adult↗