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Biomedical subjects

G F Marx

Publications and source records attributed to G F Marx.

At least 73 records · Page 4Linked to original sources
PubMed1982

Chloroprocaine.

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Anesthetics, Local↗
PubMed1982

A comparison of the response to suxamethonium in post-partum and gynaecological patients.

The response to suxamethonium was assessed in 20 women undergoing tubal ligation on the first or second post-partum day and in 20 women undergoing interval tubal ligation. The dose of suxamethonium which produced 80% depression of control twitch height was significantly lower in the puerperal patients. Similarly, recovery times following injection of a 20-mg bolus of the drug were significantly longer in the post-partum than the non-obstetric group. Cholinesterase activity, determined in six post-partum women, was inversely related to the time to maximal recovery. Thus, smaller doses of suxamethonium are required in the early puerperium.

Adult↗
PubMed1981

Is pre-eclampsia a disease of the sexually active gravida?

Observation of families present in Labor Rooms has suggested that pre-eclamptic parturients are usually accompanied by a male companion while young parturients without pre-eclampsia are attended by a female family member. Consequently, 72 unselected teenage parturients were questioned about their sexual activity during pregnancy. Pre-eclampsia was diagnosed in 22; all had sexual activity after conception, 19 during the entire course of pregnancy and three during the first trimester only. Thirteen parturients who denied sexual activity during pregnancy did not develop pre-eclampsia. The remaining 37 parturients were sexually active but pre-eclampsia did not occur. The etiology of pre-eclampsia is enigmatic. The concept of a sexually-related origin provides possible explanations for the lack of the disease in animals as well as for certain facts about the disease in humans.

Animals↗
PubMed1980

Brachial and femoral blood pressures during the prenatal period.

In 202 young primigravidas, right-sided brachial and femoral arterial pressures were recorded in both supine and left lateral positions during prenatal visits in the second and third trimesters. Roll-over tests were performed in 78 of these. Position-related falls predominantly in femoral artery pressure--indicative of aortic compression-were demonstrable earlier and with greater frequency than falls predominantly in brachial artery pressure-indicative of caval compression. While the sequelae of caval compression were perceived by the gravida, those of aortic compression were not. Therefore, education to the risks of the supine position should start early in pregnancy. There was no relationship between decreases in blood pressures and subsequent development of pre-eclampsia. Roll-over tests were positive in 45 gravidas (58%) and pre-eclampsia developed in 15 (33%). Roll-over tests were negative in 33 gravidas (42%) and pre-eclampsia developed in two (6%). This difference was significant at the 0.02 level.

Adolescent↗
PubMed1980

Detection and differentiation of metabolic acidosis in parturients.

Base deficit and blood glucose were measured in 36 laboring women in whom metabolic acidosis was clinically suspected. Of 15 parturients, 11 showed presumptive evidence of lactacidemia, two ketoacidemia, and two a combination of both. Differential diagnosis is important since therapy differs: ketoacidosis is treated with intravenous glucose, lactacidosis is treated with continuous segmental extradural block.

Acidosis↗
PubMed1980

Maternal bearing down efforts--another fetal risk?

A prospective study of 12 unmedicated pregnant women in the second stage of labor was undertaken to assess the effects of bearing down efforts on brachial and popliteal blood pressure. Inferior vena cava compression, usually detected by reductions in mean and/or pulse pressure in the brachial artery, did not occur at any time, whether or not the uterus was displaced to the left. Abdominal aortic compression, suggested by popliteal pressure fall, was maintained into the second stage of labor, was aggravated when the women bore down, and was alleviated only when bearing down efforts ceased and the uterus was displaced to the left. Bearing down efforts are therefore yet another mechanism by which distal aortic and possibly uteroplacental blood flow can be prejudiced. Their avoidance can be advantageous to the fetus at risk.

Blood Pressure↗