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Biomedical subjects

G Esser

Publications and source records attributed to G Esser.

At least 73 records · Page 4Linked to original sources
PubMed1982

[Gastrectomies in the elderly as curative and palliative operations (author's transl)].

Out of 422 patients operated on for gastric carcinoma from 1970-1980, 152 were older than 70 years. We performed a total resection of the stomach on 145 patients: 63 were 60-69 years old, with a 14% mortality; 36 were 70-79 years old, with a 25% mortality. In curative gastrectomies, the mortality was 8% in patients in their seventies (4 cases out of 48) and 12% in their eighties (3 cases of 25). In additional resection of neighbouring organs (liver, colon, and pancreas) mortality was only increased to 17% in the seventh decade and 20% in the eighth. Therefore, radical surgery for carcinoma of the stomach in form of a gastrectomy is justified even in older people, as there is a curative chance. In palliative gastrectomies the mortality has been too high: 33% (5 out of 15) in the seventh decade and 58% (7 out of 12) over the seventh decade. Palliative gastrectomies are only justified in older people if there are special indications.

Adult↗
PubMed1982

[Embolization of the splenic artery. Emergency therapy in varices hemorrhage and in hypersplenism].

In bleeding of oesophageal varices with resistance to common treatment embolisation of the splenic artery causes depression of the portal hypertension by forty per cent. Thrombosis of the splenic or portal vein as in splenectomies are not to be expected. The splenic vein remains open for later spleno-renal anastomosis. By occlusion of the splenic artery we were successful in stopping oesophageal bleeding. In a patient with dominant hypersplenism in portal hypertension the severity of the syndrome decreased after embolisation of the splenic artery. Thrombocytes, leukocytes and gammaglobulin increased.

Embolization, Therapeutic↗
PubMed1980

[Effect of oxygen in the tympanum on inner ear function (author's transl)].

Possible effects of extreme variations of oxygen concentration from 0% to 100% in the tympanic lumen on inner ear function were investigated through animal experiments. The experiments were performed with Ketanest anaesthetized cats under short-time acoustic irradiation (3 min 115 dB, pink noise). Inner ear function was measured by means of the stapedius reflex audiometry. On the nitrogen-flushed side (pO2 approx. 0%), the stapedius reflex threshold dropped significantly more after high-frequency irradiation than on the O2-flushed side. Even without acoustic irradiation the stapediusreflex threshold clearly recedes with the tympanic cavity being nitrogen-flushed. This shows that inner ear function in the cochlear base area depends on oxygen concentration in the tympanic lumen. It is pointed out that interrelations between disturbances of tubal and tympanic functions on the one hand, and internal ear function on the other hand may exist.

Animals↗
PubMed1980

[Effectiveness of continuous drainage in diffuse bacterial peritonitis].

From 1975 to 1977 we carried out postoperative, continuous peritoneal lavage of th abdomen in 41 patients with diffuse bacterial peritonitis. Although the peritonitis was arrested more frequently and earlier, comparison to 71 patients treated conventionally since 1970 showed an increase of wound complications and a prolongation of hospital stay from 25 to 44 days. The higher frequency of complications led to increased lethality from 42% to 54%. The harm by continuous peritoneal lavage out-weights the advantages, except for stercoraceous peritonitis.

Adolescent↗
PubMed1979

[Audiological findings in cases of acoustic neuromas, cerebellopontine angle and brain tumors (author's transl)].

The study contributes to improve, audiological diagnostics of central auditory path lesions and attempts, through the comparison of audiological and neurosurgical findings of 15 patients, to refer certain auditory lesions caused by cerebral tumors to topodiagnostically characteristic audiological symptoms. The audiological findings obtained through 7 generally accepted test methods from 6 patients with an acusticus neurinoma indicate a labyrinthine but not a central symptomatic picture while 4 patients with a pontine-angle tumor present a chiefly central hearing defect which, as regards the constellation of findings, clearly differs from the central hearing defect of 3 patients with a pontine tumor. Two patients with tumors in the lateral ventricle area merely show, from the audiological point of view, a lack of contralateral dichotic discrimination.

Audiometry↗
PubMed1979

Antiphytoviral activity of 2,4 dioxo hexahydro triazine.

Three treatments with 2,4 dioxo hexahydro triazine (DHT) significantly reduced the concentration of potato virus X (PVX) in systemically infected tobacco plants. In hypersensitive plants DHT caused a reduction in the number of local lesions produced by PVX. In systemic and hypersensitive hosts, treatment with DHT resulted in a more or less marked reduction in the concentration of, and in the number of local lesions caused by, potato virus Y (PVY), potato virus A (PVA), tobacco mosaic virus (TMV), and cucumber mosaic virus (CMV). Three days after treatment with DHT the incorporation of 32P into TMV RNA was significantly reduced, while that into host RNA was less affected.

Antiviral Agents↗
PubMed1979

[Dioxohexahydrotriazine, a new synthetic antiphytoviral compound (author's transl)].

This paper reports the first results of studies made to determine the antiviral activity of dioxo hexahydro triazine, a newly developed antiphytoviral compound. After treatment with dioxo hexahydro triazine, the concentration of helical potato virus X in leaves of Nicotiana tabacum "Samsun" was found to be considerably reduced in both the serological test and local lesion test conducted on Nicotiana glutinosa at temperatures of 14 degrees C +/- 3 degrees C. In secondarily infected leaves, the reduction of the concentration of potato virus X in the range of from 1 mol/l to 10(-3) mol/l was so that it was no longer possible for viruses to be detected serologically. In vitro, however, dioxo hexahydro triazine, which was added to the inoculum, did not produce a significant change in the activity of the virion of potato virus X. Therefore, it is reasonable to assume that dioxo hexahydro triazine tends to affect replication steps of viruses. The use of dioxo hexahydro triazine also had the effect of greatly and highly significantly reducing the concentration of the isodiametric cucumber mosaic virus.

Antiviral Agents↗
PubMed1978

[Decompression technique for ileus: emptying of the intestine with the fingers (author's transl)].

Intestinal obstruction and distension with stasis of the intestinal contents have to be dealt with simultaneously. Opening of the small intestine for aspiration may cause infection and is not necessary. Aspiration via a Miller-Abbot tube is complicated and time consuming. Beginning at the proximal end of the jejunum the contents of the small intestine can be emptied without risk into the stomach by digital pressure. The contaminated intestinal contents can be aspirated via a gastric tube, relieving distension and restoring intestinal circulation and motility. The simplicity of this method, its immediate effect, and its lack of complications are evident.

Humans↗
PubMed1976

[Surgical procedure in acute variceal hemorrhage (author's transl)].

The author recommends various general rules to be observed in the surgical treatment of acute variceal hemorrhage: 1. attempts to arrest the hemorrhage by conservative means are always justified in the case of variceal bleeding, but should be comprehensive, and both patient and staff should first be prepared for surgery in case it should become necessary: 2. if when the GI tract is free of blood the indications for surgery are found to be present, a shunt should be constructed at once (Crile's stage A); 3. if hemorrhage starts again after carefully monitored release of the ballons of the Sengstaken-Blakemore tube, conservative measures should be carefully applied again at once. If an experienced endoscopist is available, paravariceal sclerosing injections should be given at this point. Otherwise a shunt operation is indicated (Crile's stage B). In patients in whom liver tolerance is poor (Crile's stage C), transhoracic dissection of the esophageal varices is indicated as the only possible, definitive treatment.

Acute Disease↗
PubMed1976

[Therapeutic results in the treatment of otitis media in children with and without cleft palate (author's transl)].

Therapeutic results in the treatment of secretory otitis media were compared in children with and without cleft palate. The children were treated by the implantation of a ventilation tube. Pre- and postoperative data of a total of 551 patients were evaluated by a computer system. Following results were obtained: 1. Severity of change in the mean air-bone gap in patients with and without cleft palate was nearly the same. 2. The men airbone gap in both series after treatment showed no significant difference. 3. After evaluating impedance measurements, children without cleft palate showed a slight improvement of pressure patterns in the middle ear, on the contrary, children with cleft palate showed a significant pressure decrease. --Because of deterioration of pressure pattern in children with cleft palate, in spite of intensive treatment, implantation of a ventilatory tube for a longer period is necessary.

Child↗