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Biomedical subjects

G E Burch

Publications and source records attributed to G E Burch.

At least 91 records · Page 5Linked to original sources
PubMed1977

A spray for pain.

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Chlorofluorocarbons, Methane↗
PubMed1977

EMC viral infection of the coronary blood vessels in newborn mice: viral vasculitis.

The coronary arteries, veins and capillaries of newborn mice experimentally infected with encephalomyocarditis (EMC) virus were studied histologically and electronmicroscopically. Damage to these coronary vessels was patchy. Some lesions were extensive, particularly when adjacent to areas of myocardial damage. The histological findings consisted of swelling of adventitial and endothelial cells pyknosis, and polymorphonuclear leucocyte and round cell infiltration. Histological and ultrastructural changes occurred in all three layers of the vessels. EMC viral crystals were found electronmicroscopically in the adventitia of the coronary arteries and veins. Ultrastructural lesions typical of virocytonecrosis were frequently noted in association with viral crystals, establishing the viral etiology of the lesions. These findings lend support to the concept that the patchy atherosclerotic and arteriosclerotic lesions found in the coronary vessels of man may represent healed lesions of previous viral damage.

Animals↗
PubMed1977

The special problems of heart disease in old people.

The major difference between heart disease in the old and the young is that elderly people almost have one or more other major, even life-threateninng conditions. These associated diseases challenge the physician in establishing a diagnosis and prognosis, understanding the pathogenesis of the symptoms and signs, and determining the best managemnt. Another important difference is that old persons have senescent changes in all organ systems, whether the heart is normal or diseased. Dyspnea, especially on exertion, is common, and so is edema of the feet and ankles. Chest x-rays show changes typical of old age, e.g., small lung fields, mild to moderate pulmonary fibrosis, and calcium plaques in the aorta. In the absence of cardiac disease, the heart is normal in size or even small. Translationg experience in managing heart disease in young patients to elderly patients must be done cautiously. Old people tend to be confused, delicate, mentally and physically slow, feeble, and unreliable, and they are more sensitive to most-if not all-drugs, especially digitalis. The physician should see them often and question them routinely about their symptoms, signs, and medication. Decisions on management should not be hurried, except in an emergency situation.

Aged↗
PubMed1976

Of venture research.

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Research Support as Topic↗