Search PubMed⌕ Search

Biomedical subjects

G Dutau

Publications and source records attributed to G Dutau.

At least 127 records · Page 7Linked to original sources
PubMed1977

[A symptomatic parathyroid adenoma. Value of parathyroid hormone determination through selective catheterization of the thyroid veins].

A parathyroid adenoma is reported in a girl aged 12 years in whom hypercalcaemia was discovered by chance. Investigation of calcium metabolism suggested the diagnosis of hyperparathyroidism and studies of the urinary cyclic AMP and determination of the plasma parathyroid hormone concentration further added to the evidence. The diagnosis of parathyroid adenoma was made after determination of the parathyroid hormone concentration at various sights during selective catheterization of the tyroid veins. This was confirmed at surgery. In this patient the place of catheterization of the inferior thyroid veins in the early diagnosis of primary hyperparathyroidism is discussed.

Adenoma↗
PubMed1977

[Recurrent bronchopneumopathies caused by gastroesophageal reflux in children. Clinical, x-ray and histologic studies of 36 cases].

The respiratory symptoms of gastro-oesophageal reflux, which sometimes includes massive and fatal inhalation, are well-known in infants. In older children the digestive signs are not clinically evident and the reflux mainly, if not exclusively, can be translated by recurring respiratory symptoms. The series of 36 cases presented in this work concerns children between 3 months and 15 years old, for whom the first signs were respiratory, with often a silent gastro-oesophageal reflux for several months, and even several years in some cases. The physiopathology of the respiratory symptoms concerns principally the repeated alimentary aspiration and/or gastric content during nocturnal decubitus. The pulmonary lesions caused by the reflux can be either localized, with atelectasis, obstructive emphysema or bronchiectasis, or generalized with granulomatous reactions around the food particles. Other respiratory conditions such as asthma or cystic fibrosis can be also associated with gastro-oesophageal reflux. The diagnostic criteria are discussed.

Adolescent↗
PubMed1976

[Stimulation by the propranolol-glucagon test of somatotropin secretion in 71 children. Results, statistical study and comparison with the insulin-arginine test].

Two tests of stimulation: insulin + arginine and propranolol + glucagon were successively performed in 62 children who were either normal or had essential growth retardation. Average peak value was 10.6 +/- 1.1 ng/ml in the first test and 22.8 +/- 1.4 ng/ml in the second. In 56 cases the response obtained with propranolol + glucagon was higher than that obtained with insulin + arginine. Twenty-four false negative results were obtained employing insulin + arginine, stimulation by propranolol + glucagon resulting in normal values. The determination of the confidence interval at 95% and of the 3rd percentile did not allow to establish the lower threshold for the insulin + arginine test. For the propranolol + glucagon test 7.6 ng/ml for the interval at 95% and 8 ng/ml for 3rd percentile were found as minimal threshold. Therefore, a response below 8 ng/ml should be considered as pathological with the latter test.

Adolescent↗
PubMed1976

[Attempt at potentiation of the action of L-dopa on the secretion of growth hormone by benserazide, disulfiram and propranolol].

Two tests of stimulation of growth hormone secretion were performed in 3 groups of normal children. In the first test L-Dopa was used on its own; in the second, L-Dopa was combined with Benserazide (group A), with Disulfirame (group B), or with Propranolol (group C). In group A the mean peak value after L-Dopa was 9.1 +/- 1.6 ng/ml; with the combination of L-Dopa and Benserazide it was 12.4 +/- 2.4 ng/ml. The difference between the means is not significant. In group B the mean peak value after L-Dopa was 8.9 +/- 3.6 ng/ml; with the combination of L-Dopa and Disulfirame it was 14.5 +/- 4.4 ng/ml. The difference is not significant. In group C the mean peak value after L-Dopa was 9.8 +/- 2.6 ng/ml; with the combination of L-Dopa and Propranolol, it was 10.1 +/- 1.9 ng/ml. Again the difference is not significant. These findings do not provide evidence in favour of the effect of L-Dopa on the secretion of growth hormone being facilitated by an inhibitor of L-Dopa decarboxylase (Benserazide) or of Dopamine beta hydroxylase (Disulfirame), or by a beta blocking agent (Propranolol). The mechanisms of action of L-Dopa and of the various combinations studied are discussed.

Adolescent↗
PubMed1975

[Bronchography in children].

In spite of improvement in the exploratory techniques of the respiratory tract, tracheo-bronchography preserves numerous indications in the study of children's congenital or acquired bronchopneumopathies. The main indications of this investigation consist in the detection of bronchectasies or in the exploratory study of chronic and relapsing bronchial diseases. The investigation makes possible to precise the severity of the disease, to value the results of the medical management and, at last, to select the patients amenable to surgery. Another indications are to be found in the appraisal of some malformative broncho-pneumopathies, with special reference to lung hypoplasias and sequestrations. The technical conditions of the investigation have largely benefited of short duration general anesthesy and of various material improvements (televised fluoroscopy, orientable catheters of small calibre).

Adolescent↗
PubMed1975

[Association of Fanconi's disease and hepatic tumor in a patient undergoing long-term androgen treatment].

A Fanconi's disease was discovered in a 9 1/2 year old girl. She received androgens daily and died with a severe aplastic attack after 4 years of evolution. Hepatic involvement of treatment with androgens was regularly checked. Autopsy however, showed a multinodular adenoma of the liver without any malignant manifestation. Relationships between aplastic anemia, long-term treatment with androgens and tumour of the liver are discussed. The difficulty of in vivo diagnosis is emphasized.

Adenoma↗