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Biomedical subjects

G Dev

Publications and source records attributed to G Dev.

24 records · Page 2Linked to original sources
PubMedDate not supplied

Early biologic behavior of bone grafts. A fine needle aspiration cytology study.

OBJECTIVE: To conceptualize, with fine needle aspiration cytology (FNAC), the early cellular events occurring in and around fresh autogenous and allogenic bone grafts during the first 40 postimplantation days. STUDY DESIGN: Forty-eight cases of bone grafts were studied by FNAC at serial intervals of 10, 20, 30 and 40 postimplantation days. Twenty patients were recipients of autogenous grafts, 16 received 0.6N HCI partially decalcified allogenic bone implants, and 4 received combined autogenous and allogenic bone grafts (included in the allograft group). There were eight control cases of closed fracture shaft femur, which were managed conservatively. RESULTS: The initial cellular responses in autogenous grafts, allografts and controls appear to be a part of the nonspecific reparative process followed by a more specific phase, with a steady increase in relative lymphocyte count from the 20th day onwards. Osteogenesis, as judged by osteoblasts and osteoclasts, was also comparable. CONCLUSION: Partially decalcified allografts appear to be a good substitute for autogenous bone grafts in clinical practice when adequate autogenous material is not available. FNAC is a good technique for studying bone graft responses without interfering with graft uptake. It is helpful in the early detection of subclinical infection or any other pathology at the graft site.

Adolescent↗
PubMedDate not supplied

Fine needle aspiration cytology of a lipoblastoma.

A lipoblastoma, an uncommon tumor of childhood that can be mistaken for a liposarcoma, was preoperatively diagnosed by fine needle aspiration cytology. The characteristic features on the cytologic smears were the presence of immature fat cells in the form of spindle-shaped cells, stellate cells and vacuolated lipoblasts along with lipocytes. The cytologic diagnosis was confirmed by histologic study of the excised tumor.

Arm↗
PubMedDate not supplied

Malignant ameloblastoma. A case report.

The cytologic features of malignant ameloblastoma, a rare tumor of the jaw, are described. Fine needle aspiration smears showed high cellularity, with small basaloid and polygonal epithelial cells with mild to moderate pleomorphism lying singly or in clusters. In Giemsa-stained smears, pinkish stroma with stellate cells or irregularly shaped nuclei and isolated spindle cells were seen in the background. Histopathology of the tumor showed sheets of cells with features of malignancylike atypical mitosis and vascular invasion. The tumor cells stained positive for keratin on immunohistochemistry. A review of cytology smears revealed that the features were sufficiently characteristic of an ameloblastoma, but it was difficult to label the lesion malignant on fine needle aspiration cytology.

Adult↗