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Biomedical subjects

G Delgado

Publications and source records attributed to G Delgado.

At least 127 records · Page 7Linked to original sources
PubMed1979

Delayed cerebral radionecrosis following treatment of basal cell carcinoma.

Delayed radiation necrosis of the brain was found around the right ear in a patient with basal cell carcinoma of the skin. Five months after excision, the tumor recurred. The patient received 5,575 rads in 24 doses during radiotherapy. Thirteen months later, the patient had cerebral radionecrosis, which was the cause of death. At autopsy, typical radionecrotic lesions of the temporal lobe were found. There were widespread metastases.

Brain Diseases↗
PubMed1979

Intestinal anastomoses after radiation therapy by surgical stapling instruments.

The use of automated stapling instruments in 17 patients requiring intestinal surgery following irradiation therapy for gynecologic malignancies has been reviewed. Fifteen of these patients also had other medical problems thought to inhibit optimal anastomotic healing: malnutrition, persistent intraabdominal cancer, uremia, hypoalbuminemia, and recent antineoplastic chemotherapy. Although these conditions severely test a method of intestinal anastomosis, no patient had a complication involving the intestinal anastomosis. The use of these stapling instruments reduced both the operating time and the contamination of the peritoneal surfaces by bowel content, thereby improving the postoperative recovery of these patients. The favorable results and the secure anastomoses justify the continued use of stapling instruments in gynecologic oncology patients with prior irradiation therapy.

Female↗
PubMed1978

Plastic procedures in cancer of the lower genital tract.

Plastic procedures were performed on 12 patients with cancer in situ of the vulva or vagina or after pelvic exenteration. All patients are alive and well on follow-up from four to 47 months with no evidence of recurrence. Plastic procedures are very important in treatment of cancer of the lower genital tract. The split-thickness graft used in this study is optimal in terms of treatment appearance, and restoration of sexual function.

Adult↗
PubMed1978

Benign glandular inclusions in para-aortic lymph nodes in women undergoing lymphadenectomies.

Benign glandular inclusions in para-aortic lymph nodes are a relatively common occurrence. The chance of finding these benign glandular inclusions in the para-aortic lymph nodes is dependent on the intensity with which one searches. In our series of 106 para-aortic lymphadenectomies performed on patients with gynecologic malignancies, there were five patients in whom these benign Müllerian rests were found. Other series report up to a 40.8 per cent incidence of benign inclusions in nodes of patients with cervical cancer. They may have been either congenital or acquired. It is critical that these Müllerian tissues are not confused with metastatic disease. The significance of these benign glandular inclusions is discussed.

Adenocarcinoma↗
PubMed1978

Colposcopically directed cone biopsies in the management of cervical intraepithelial neoplasia.

Thirty-three patients with severe dysplasia and carcinoma in situ had a colposcopically directed cone biopsy in the operating room immediately prior to vaginal hysterectomy. In 3 cases (9%), the hysterectomy specimen showed the same type of residual disease as in the cone biopsy; in the remainder no residual disease was evident in the hysterectomy specimen. If colposcopically directed biopsies were performed, the long-term debate over the use of cone biopsy or hysterectomy for intraepithelial neoplasms would be resolved. Selected patients could be treated adequately by cone biopsy with a small number of patients requiring hysterectomy as indicated by direct examination with the colposcope.

Biopsy↗
PubMed1978

Rose Bengal plate agglutination and counterimmunoelectrophoresis tests on spinal fluid in the diagnosis of Brucella meningitis.

Rose Bengal and counterimmunoelectrophoresis, two tests that detect antibodies against different structural antigens, when carried out on spinal fluid permitted rapid diagnosis of human Brucella meningitis. The Rose Bengal test was positive in five out of five patients studied, and counterimmunoelectrophoresis was positive in all but one. The Brucella meningitis was characterized by an increase of immunoglobulin G in the cerebrospinal fluid.

Agglutination Tests↗
PubMed1978

Survival and complications in cervical cancer treated by pelvic and extended field radiation after paraaortic lymphadenectomy.

Over a 3 year period, 49 patients with invasive cancer of the cervix underwent paraaortic lymphadenectomy. Of this group, 18 were stage lb, with cervix 3 cm or smaller, and were treated by radical hysterectomy. All had negative paraaortic nodes. The remaining 31 patients had more advanced disease and underwent radiation therapy in addition to the paraaortic lymphadenectomy. Thirteen patients with positive paraaortic nodes were treated with extended field radiation to the level of the diaphragms with 4,500 rad plus intracavitary radium applications. The remaining 18 patients with negative paraaortic nodes were treated to the fifth lumbar vertebra with 5,000 rad plus radium applications. The age of the patients and stage of the disease were similar for both groups. After 13-36 months of follow-up, the survival rate was 38% for patients with positive nodes compared to 72% for those with negative nodes. About half of both groups suffered complications. More study must be given to alternative treatments of advanced carcinoma of the cervix.

Cobalt Radioisotopes↗
PubMed1978

Intraoperative radiation of the paraaortic nodes in cancer of the uterine cervix.

Intraoperative electron beam irradiation is being used for the therapeutic and prophylactic treatment of the paraaortic nodes in cancer of the uterine cervix. A Varian 18 meV accelerator is employed at an electron energy setting of 6--18 meV. Special aluminum and lucite collimators allow visualization of treatment area and keep the uninvolved small bowel out of the treatment beam. A one-time dose of 2000 rads is delivered in 4 minutes. The procedure presents no special surgical problems, is well tolerated, and appears as a promising supplement in cases where abdominal exploration for surgical staging of cervical carcinoma is carried out.

Adult↗