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Biomedical subjects

G D Dobben

Publications and source records attributed to G D Dobben.

At least 37 records · Page 2Linked to original sources

Evaluation of the regional blood circulation of the hindbrain by dynamic computed tomography.

Permanent or transient reduction of blood flow to the hindbrain is often responsible for symptoms of disequilibrium, dizziness and occasionally sensorineural hearing loss. Recent advances in CT technology and the development of continuous rapid rotational CT brain scanning now permit a practical and relatively non-invasive method for evaluation of regional brain circulation. It is the purpose of this presentation to review displays of normal CT hindbrain circulation and compare them with displays from patients with hindbrain ischemia. Dynamic CT provides a useful clinical index of brain blood circulation and can be used to detect and differentiate insufficiency due to pathology of the brain, of the artery supplying it, or of the cardiovascular system. Finally, the quantitative hemodynamic benefit from surgery of the carotid or vertebral arteries can be properly evaluated by this technique.

Brain Stem↗

Evaluation of brain circulation by rapid rotational computed tomography.

Continuous rapid rotational CT brain scanning now permits the study of brain circulation. The parameters studied are related to the transit time of circulation and to blood flow differences within small portions of the brain. For ease of description, this study is called regional brain circulation (rBC). This preliminary report is based on our experience with 75 consecutive cases studied since August 1, 1978. Displays of normal brain, cerebral ischemia, and arteriovenous malformations are analyzed in this paper. The normal graphic display of rBC includes peak concentration, transit time, washin and washout phases. Clinical application to medical-surgical treatment is illustrated.

Aged↗

Bicaudate index in computerized tomography of Huntington disease and cerebral atrophy.

Ventricular sizes on computerized tomographic (CT) scans were compared in seven patients with Huntington disease, 20 patients with cerebral atrophy, and 20 normal controls. The bicaudate index--the ratio of the width of both lateral ventricles at the level of the heads of the caudate nuclei to the distance between the outer tables of the skull at the same level--significantly discriminated among the three groups. The bicaudate indices were: Huntington disease 0.209 +/- 0.007, cerebral atrophy 0.121 +/- 0.006, and controls 0.092 +/- 0.003.

Adult↗