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Biomedical subjects

G Coscas

Publications and source records attributed to G Coscas.

At least 163 records · Page 9Linked to original sources
PubMed1987

Eight-year follow-up of central serous chorioretinopathy with and without laser treatment.

A long-term retrospective study was conducted on two groups of patients affected with typical central serous chorioretinopathy (CSCR). One group was not treated and the other was treated by direct argon laser photocoagulation. CSCR shows a long-term good prognosis of visual acuity. The visual acuity of laser-treated eyes improves significantly (P less than or equal to 0.05), particularly in single focus cases (P less than or equal to 0.01). Unfortunately, these results cannot be statistically compared to the natural course of the non-treated patients because of the initial inhomogeneity of the two groups. Laser treatment did not produce any long-term complications. The recurrence rate in treated and untreated eyes was similar.

Adult↗
PubMed1987

Adenocarcinoma of retinal pigment epithelium.

This report describes a 41-year-old man with an intraocular tumour misinterpreted clinically as choroidal melanoma. The fluorescein angiographic features were not fully characteristic of uveal malignancy, and indeed histopathology revealed the diagnosis of adenocarcinoma of the retinal pigment epithelium. It is suggested that, in cases with the fundus and angiographic findings described here, the rare possibility of adenocarcinoma of retinal pigment epithelium should be kept in mind. Of particular interest were the changing pathological findings in the various parts of the tumour, which paralleled the fluorescein angiographic pattern.

Adenocarcinoma↗
PubMed1987

[Occlusion of the central retinal vein with occlusion of a cilioretinal artery: apropos of 7 cases].

The seven patients described where suffering from simultaneous occlusion of the central retinal vein and cilioretinal artery. All underwent complete ocular examination including fluorescein angiography and visual field assessment, and general investigation with special emphasis on blood and vascular disorders. All patients had been observed for at least one year. Their age ranged from 35 to 60 years (mean: 46 years); fundus examination showed a common pattern consisting of mild edematous central retinal vein occlusion with few hemorrhages as well as a large area of retinal infarction due to cilioretinal artery occlusion. Despite the presence of this large infarcted area, this cases were very different from the ischemic forms of central retinal vein occlusion since in all cases perfusion of the retinal capillaries in the cilioretinal area recovered in a few days. In 4 of 7 cases, fluorescein angiography also disclosed sectorial hypoperfusion of the optic disc at the acute stage. Recovery of venous occlusion occurred in 3 to 14 weeks and the visual acuity outcome was fairly good, as in 5 of the 7 patients, visual acuity reached at last 0.5. No embolic disease was detected but 3 patients had severe migraine. The pathogenesis of this condition remains unclear. Although cilioretinal infarction is usually thought to be secondary to central retinal vein occlusion, the possible role of primary occlusion of the cilioretinal artery is considered.

Adult↗
PubMed1986

Ocular fluorophotometric and angiographic findings in toxemia of pregnancy.

Ocular fluorophotometry was performed in 24 patients with hypertension due to toxemia of pregnancy and in ten normal subjects. Patients showing features of accelerated hypertension in the fundus (eg, hemorrhage, cotton-wool spots, and disc edema) were excluded from the study. Fluorescein concentrations in the aqueous and posterior vitreous increased significantly in toxemic patients compared with those in normal subjects; the blood-aqueous barrier was disrupted earlier than the blood-retinal barrier. Nevertheless, these barriers were only disrupted when the arterial diameter was altered. Ocular fluorometric abnormalities disappeared after delivery in all but two cases.

Eye↗