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Biomedical subjects

G Corrao

Publications and source records attributed to G Corrao.

At least 91 records · Page 5Linked to original sources

[Reliability and completeness of an integrated epidemiologic system of acute viral hepatitis].

An integrated epidemiological system for the surveillance of acute viral hepatitis (Seiva) has been performed in Italy. Aim of the present work is to evaluate diagnostic completeness and reliability of the surveillance system in the Piedmont Region. Results show that 15% of Acute Viral Hepatitis are not reported by the system and that the potential diagnostic errors are 7.3% of the cases.

Acute Disease↗

Immune response to anti-HBV vaccination: study of conditioning factors.

The Authors studied the immune responses of 691 health care workers who were given HEVAC B vaccine (455 subjects) and HB Vax vaccine (216 subjects). The immune responses were correlated with data obtained by questionnaires: age, sex, B.M.I., drinking habits, smoking. The results showed correlation between these variables and immune response to vaccine.

Adult↗

Uterine sarcomas. A retrospective study of 17 cases.

Seventeen documented cases of uterine sarcoma were studied in an effort to establish the relationship between prognostic factors and patients' survival. The analysis of prognostic factors showed that there was a significant difference in survival between patients with stages I and II tumors and those with more advanced lesions. It has been also noted that prognosis was worse in patients with history of previous abortions and in patients who had abdominal or pelvic pain.

Aged↗

HBV pre-vaccination screening in hospital personnel: cost-effectiveness analysis.

The purpose of this study was to identify the most cost-effective method for screening subjects for hepatitis B vaccination. Such a method would ideally permit detection of all susceptible individuals at the lowest possible cost. Two-hundred-five hospital workers from the Piedmont region of Italy participated in the study. The sero-epidemiological conditions of this group with regard to hepatitis B markers was representative of hospital workers in this region as a whole. All subjects, excluding carriers, persons with anti-HBs titers greater than or equal to 10 mIU and subjects positive for anti-HBc at a 1/100 dilution, were vaccinated. Their responses were evaluated 15 days and 1 month after vaccination. The presence of a booster effect following vaccination was correlated with the immunological status of the subject at the time of pre-vaccination screening. In the light of the results obtained, 5 screening procedures and the procedure of vaccination without screening were evaluated. The most cost effective screening strategy proved to be that of sequential testing for anti-HBc, anti-HBs and finally HBsAg and vaccination of the following subjects: those who were negative for anti-HBc, those who were anti-HBc-positive with anti-HBs titers 10 less than mIU and those who were HBsAg negative.

Cost-Benefit Analysis↗

Head shape and size and body weight in the newborn infant.

Biparietal diameter, occipitofrontal diameter, cephalic index and occipitofrontal circumference were measured in 108 newborns delivered at term by cesarean section. Statistical analyses were carried out to assess the relationship between each of the parameters and birth weight. Particular attention was paid to the cephalix index/birth weight, the former being assumed as an expression of head shape. No correlation between birth weight and cephalic index was observed. Birth weight best correlates with occipitofrontal circumference.

Birth Weight↗

[Hepatitis A and B virus infections in refuse workers in Asti].

The authors have examined Hepatitis A and B virus infection risk in 93 dustmen and sewer workers. It has non been found a risk correlated with employment, though for some of them, with peculiar functions, the HBV and/or HAV serological markers prevalence rates were higher than in the remaining of the studied population.

Adult↗

Concentrations of nitrates in drinking water and incidence of gastric carcinomas: first descriptive study of the Piemonte Region, Italy.

A descriptive epidemiological research, within the Piemonte Region was carried out, to consider whether there is an association between concentrations of nitrates in drinking water and the incidence of gastric carcinomas. The results indicate that an association does exist, but also that concentrations of nitrates higher than 20 mg/l in drinking water are a risk factor for people exposed.

Female↗

[Proposals for the surveillance of persons exposed to aromatic amines].

The AA present the results of an epidemiological investigation in a rubber factory, where aromatic amines are used. Environmental monitoring allowed to acquired informations about environmental concentrations of aromatic amines, to identify their physical condition and so to individuate a map risk in this factory. The biological monitoring was conducted to acquire epidemiological information from archives of usual biological check up. The AA propose a methodology for epidemiological survey of people exposed to aromatic amines.

Air Pollutants, Occupational↗

[Environmental pollutants and karyologic effects. Usefulness of environmental and biological monitoring].

The results of a study carried out on a group of workers exposed to numerous pollutants (HCl, NaOH, ZnCl2, Sn, Pb, ecc.) in an industrial environment are reported. The research was broken down into two parts: 1) drawing up of a map of environmental pollution; 2) evaluation of the biological exposure of individuals submitted to control. The blood level of Pb was assessed in chosen subjects as a biological indicator of exposure and, at the same time, lymphocyte cultures were prepared in order to highlight any increase in chromosome exchanges and chromosome aberrations.

Air Pollutants↗

Outcome variables in the evaluation of alcoholics' treatment: lessons from the Italian Assessment of Alcoholism Treatment (ASSALT) Project.

The observational evaluation of alcoholics' treatments requires a combined analysis of alcoholic behaviour during treatment and of adherence to therapeutic programmes. The application of survival analysis techniques in this setting has been explored in this study. Two hundred and seventy alcoholics admitted to 15 Italian treatment units in a 1-year period were followed-up for 2 years, recording date and length of every recurrence episode and of definitive or transitory interruption of the planned treatment. An extensive use of several survival analysis techniques was made. The length of time between the start of the treatment and the first episode of relapse did not give a reliable measure of frequency of failures. Conversely, the length of time between the start of treatment and withdrawal appeared to be unbiased. The cumulative proportions of treatment-compliant patients (and the corresponding 95% confidence intervals) were 71% (66-76%), 63% (57-69%) and 53% (47-60%) after 6 months, 1 year and 2 years respectively from the start of treatment. Cumulative abstinence duration before withdrawal was significantly and positively associated with the risk of first, of definitive, and of every episode of treatment interruption. This first application of survival analysis techniques to the combined study of alcoholic behaviour and of adherence to treatment can improve our knowledge of treatment evaluation. Our results suggest that compliance to treatment is an objective and versatile outcome measure. Long-term follow-up studies aimed to elucidate the determinants of withdrawal should be performed.

Alcoholism↗