[Avitaminosis A disclosed by corneal perforations].
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Biomedical subjects
Publications and source records attributed to G Constantinides.
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Five cases of retinal detachment with macular hole show the effectiveness of the treatment: Vitrectomy + exchange Fluid-gas. Red krypton laser applied around macular hole is not necessary. Treatment vitrectomy-exchange Fluid gas must be performed rather than Aspiration-gas in a first attempt.
Xerophthalmia is no longer seen in Europe since the 19th century. We report the case of a female patient, aged 33, of french nationality, who presented a clinical picture of major vitamin A deficiency, self-induced and with ocular complications. An untreated long standing depressive condition appeared to be the major etiologic factor. Perforation of a desmetocele necessitated penetrating keratoplasty. Histologic corneal and conjunctival aspects are reported. Oral prescription of vitamin A resulted in considerable clinical improvement. Only 3 similar cases have been previously reported. Clinical manifestations of xerophthalmia are described along with preventive and curative therapy.
We used quantities of perfluoropropane as a substitute of vitreous in some cases of retinal detachment with vitreoretinal proliferation. It seems to be a good method compared with the injection of silicon oil for in 23 cases treated recently, the evolution of the vitreoretinal proliferation seems to have stopped better than with silicon oil. Postoperative intraocular pressure surveyance is highly advisable.
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On a basis of a series of a 130 color photographies registered under polarized light, we have studied the respective part of mass reflexions and of diffusions on the formation of fundus images. The results show that the retina is the main centre of mass reflexions which disappear in polarized light. The pigment (hemoglobin, melanin, etc...) become the main factors of the formation of fundus images. We conclude on the risks of errors which can be done by extrapolating the informations given by photography to assess the action of photocoagulation.
A case of Von Hippel Lindau disease with bilateral pheochromocytoma is reported. The diagnosis of pheochromocytoma is evoked after complications during general anaesthesia for treatment of retinal hemangioblastoma.
The authors presented two personal cases of ocular involvement by non hodgkin's malignant lymphomas. The first one concerned a 55 year-old man; initial symptoms were oedematous optic neuropathy associated to vitritis, uveitis and chorio-retinal infiltrates. The ocular symptoms did not respond to cortico-steroid therapy and lymphoma was diagnosed eight months later by histologic examination of a cerebral tumor discovered by C.T. scan. Systemic examination was normal. In spite of a cerebral radiotherapy associated to chemotherapy, uveitis and vitritis occurred in the other eye and vitreous biopsy of the most affected eye showed no cell abnormalities. The patient died two years after the onset of ocular symptoms. The second case concerned a 67 year-old woman who presented an association of absolute glaucoma secondary to uveitis with retinal detachment and neurological symptoms due to a cerebral tumor detected by C.T. Scan. Histological examination of the enucleated eye confirmed the diagnosis of centroblastic lymphoma: choroid, retina and optic nerve were involved. A data review consisted of a study of 93 cases with the same pathological conditions and permitted a discussion about the main clinical features of this affection and the different histological aspects. The following classification of the different forms of ocular lymphomas was proposed: isolated associated to cerebral and/or to systemic localizations. The management of a treatment by radiotherapy was discussed, based on the previous reports, and a prognosis of oculo-cerebral lymphomas was given.
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