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Biomedical subjects

G Carmignani

Publications and source records attributed to G Carmignani.

At least 91 records · Page 5Linked to original sources

Infrarenal cavectomy and microsurgical reconstruction of an accidentally sectioned aberrant renal vessel in a patient with renal cell carcinoma.

A case of renal cell carcinoma invading the surrounding organs and extending into the infrarenal vena cava, treated by enlarged nephrectomy, splenectomy, resection of the diaphragm and extended resection of vena cava, is presented. Special attention is paid to the diagnostic angiographic approach, to the surgical solution adopted and to the microvascular reconstruction of an injured aberrant vessel of the contralateral kidney.

Adenocarcinoma↗

Surgical hyperparathyroidism in calcium stone formers. A retrospective study of 20 cases.

Urinary lithiasis, hypercalciuria and hyperparathyroidism are strictly related diseases, and the urologist diagnoses primary hyperparathyroidism (PHP) in the majority of cases. Herein we retrospectively analyze our experience of 20 cases of surgically proved PHP, operated on in the last 4 years. Hypercalcemia was the keystone for the diagnosis of all our cases PTH radioimmunoassay on selectivity sampled blood revealed a fundamental tool in the management of patients with suspicious or certain hyperparathyroidism. It confirmed the diagnosis in all the cases and gave the preoperative localization of parathyroid adenomas in 70% of the cases. Besides, it made it possible to discriminate between parathyroid adenomas and diffuse hyperplasia preoperatively, so offering a considerable aid to the surgeon in deciding between the conservative and liberal approach to parathyroid surgery. At follow-up, 3 out of 14 cases revealed renal hypercalciuria, which could have been the cause of hyperparathyroidism, as proposed by Reiss and associates previously. The relationship between hypercalciuria and hyperparathyroidism and the problem of a new classification of parathyroid hyperfunction are discussed.

Adenoma↗

Parathyroid autotransplantation.

7 patients with diffuse parathyroid hyperplasia underwent total parathyroidectomy and microsurgical autotransplantation for diffuse parathyroid hyperplasia. 5 of 7 patients showed good function of the grafted parathyroid tissue, as checked by the separate PTH assay from the grafted versus not grafted forearm. In 1 patient parathyroid stimulation test with EDTA infusion and suppression test with calcium infusion were also performed.

Adult↗

[Testis autotransplantation in the abdominal cryptorchidism (author's transl)].

Testis autotransplantation represents an elegant and safe surgical procedure in the complex problem of the abdominal cryptorchidism. The authors report 2 cases of testis autotransplantation, in a child and in a young adult. the technique is strictly microsurgical, using the operative microscope, the microsurgical instruments and microsutures. For the control, the use of Doppler sound has proven its efficacy. The first results are encouraging and the authors conclude that such an intervention deserves to be taken into consideration when the decision to conserve an abdominal testicle is considered.

Adult↗

[Brisk postoperative bleeding in a solitary kidney successfully treated by temporary clot embolization (author's transl)].

The so called temporary embolization by percutaneous injection of autologous clot can be envisaged as the method of choice in selected cases of massive renal bleeding. The goals of this technique are to occlude the bleeding vessels until a satisfactory hemostasis is achieved and to preserve as far as possible the renal parenchyma by adopting a completely reabsorbable embolic material as the autologous clot. After a review of the literature a case is presented where a temporary embolization was performed in a young woman with brisk postoperative bleeding in a solitary kidney. The procedure was successful and the renal function was not impaired.

Adult↗

[Sub-costal xypho-umbilico flap. A new approach to the neoplastic kidney (author's transl)].

The authors suggest a new approach to the kidney tumors: the xypho-umbilical-subcostal flap incision. This incision offers the advantages of the transversal as well as of the longitudinal approaches and gives a very satisfactory exposition of the surgical field. The authors report 52 cases of renal tumors operated on with this approach in the last 5 years: because of the optimal view it allows and of the lack of complications they suggest this incision as a method of choice in the majority of the cases of renal tumor.

Humans↗

Transcatheter embilization of the hypogastric arteries in cases of bladder hemorrhage from advanced pelvic cancers: followup in 9 cases.

Bilateral transcatheter embolization of the hypogastric arteries is effective hemostatic treatment for patients with chronic life-threatening bladder hemorrhage from advanced pelvic cancers. We reviewed 9 cases in which this procedure had been done to investigate the immediate results, clinical effects, complications and late results. The minimum followup is 1 year except for 4 patients who were followed until death, which occurred in less than 1 year. Bleeding relapse occurred in only 2 cases and another embolization procedure was done in 1 case without major complications. A considerable decrease in the size of the tumor was noted in 1 patient after the bilateral hypogastric arterial embolization procedure. A rare complication, the Brown-Séquard's-like syndrome, is discussed.

Aged↗

[Transcatheter hypogastric embolization in life-threatening bladder hemorrages: immediate and long-term results (author's transl)].

Transcatheter embolization of the hypogastric arteries has become a more and more largely used therapeutic approach in mastering unrestrainable hemorrages in bladder cancer patients. In this paper the Authors report their experience with this method based on 9 cases, which could be followed for 1 year or until patient's death. The immediate and long-term results are presented and discussed. The Authors conclude that transcatheter hypogastric embolization is the best non-invasive method to handle neoplastic pelvic hemorrages.

Aged↗

Hydroxyurea in the management of chronic urea-splitting urinary infections.

The aim in the management of struvite stones is to remove all of the stones and to treat urinary infection. The bacterial species which are known to cause struvite stones produce the enzyme urease, which increases urinary pH by splitting urea and consequently causes urinary supersaturation with respect to struvite and hydroxyapatite. The use of bacterial urease inhibitors with antibiotics is a new and interesting aid in the management of chronic urea-splitting infections. We describe our experience with the use of hydroxyurea in 15 patients with chronic urea-splitting infections.

Adolescent↗

Value of selective parathormone radioimmunoassay in primary hyperparathyroidism.

Nine cases of primary hyperparathyroidism (PHP) in patients with urinary calculi are reported and discussed. Selective venous catheterization and parathormone (PTH) radioimmunoassay confirmed the diagnosis in all cases, preoperatively discriminated between adenoma and diffuse parathyroid hyperplasia, and permitted exact preoperative localization of 5 of 7 adenomas. The interest of the urologist in PHP and the usefulness of selective PTH radioimmunoassay are discussed and emphasized.

Adenoma↗

Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate.

Transcatheter arterial embolization is a useful technique to manage urological tumors. Herein we describe a new embolic material (isobutyl-2-cyanoacrylate) in 5 cases of renal cancer embolization and in 1 case of bilateral hypogastric embolization for bladder cancer hemorrhage. Isobutyl-2-cyanoacrylate provides a complete, distal and irreversible embolization, making it suitable material in cancer embolization.

Aged↗

Gelatin foam and isobutyl-2-cyanoacrylate in the treatment of life-threatening bladder haemorrhage by selective transcatheter embolisation of the internal iliac arteries.

Three patients with severe haemorrhage from inoperable bladder cancer were treated by selective transcatheter embolisation of both internal iliac arteries. The technical details, results and a rare complication are described. Both gelatin foam and isobutyl-2-cyanoacrylate (IBC) are suitable embolic materials, but we prefer IBC when possible in patients with tumour.

Aged↗