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Biomedical subjects

G Burghard

Publications and source records attributed to G Burghard.

At least 37 records · Page 2Linked to original sources

[The results of educational anti-smoking measures at the primary school level (author's transl)].

A retrospective study was made from a self-administered questionnaire distributed to 4,166 pupils aged 15 to 18, attending "Bas-Rhin" high schools, in Spring, 1979. The results demonstrate the relative effectiveness of educational anti-smoking measures when information is given to specific age groups. Information given at the primary school level results in a proportionately and significantly lower number of smokers; there was also a tendency both to smoke fewer cigarettes per day, and to choose brands having lower tar and nicotine levels. These pupils also left a greater portion of the cigarette unsmoked, i.e. they left longer cigarette butts. In addition, the number of pupils who had never smoked was greater in those groups who received information at the primary school level; and the number of ex-smokers (those who had given up smoking for at least one year) was also greater. The results emphasize the effectiveness and importance of public health measures carried out in young children.

Adolescent↗

[Current deaths due to tuberculosis in France. Analysis of 126 deaths recorded in tuberculosis sufferers in 1975 and 1976 in the Bas-Rhin region (author's transl)].

The authors present a study involving 103 cases of death during active tuberculosis and 23 cases of death as a result of complications related to sequelae of tuberculosis recorded in the Bas-Rhin region in 1975 and 1976. Whilst amongst these 103 deaths, the majority concerned elderly individuals, there were nevertheless 20% of deaths due to tuberculosis below the age of 55. The majority of these tuberculosis sufferers had advanced pulmonary lesions where specific therapy had not had time to act. A certain number of deaths could have been avoided, even in the elderly subjects. Of the 23 cases of death due to sequelae, 2/3 died of respiratory failure and 1/5 of secondary aspergillus infection, illustrating the grave prognosis in certain sequelae of tuberculosis.

Adult↗

[A self-administered questionnaire applied to 30,000 teen-agers. Assessment of this method of data collection (author's transl)].

In the French "département" of "Bas-Rhin", about 30,000 teen-agers filled in a self-administered questionnaire about respiratory symptoms, in spring 1976. The assessment of this method of data collection shows a very high response rate (99,7 p. cent). If we consider as incomplete all the questionnaires having at least one unanswered question concerning respiratory symptoms or smoking, 55,8 p. cent of them were incomplete, but for most questions non-response rate was lower than 4 p. cent. The consistency of answers was very satisfactory (mean inconsistency rate: 0,39 p. cent) and the likelihood of answers was proved.

Adolescent↗

[Hereditary antithrombin III deficiency causing recurrent thrombo-embolic problems (author's transl)].

A marked deficiency in antithrombin III (AT III) was demonstrated in a 39-year-old man suffering from recurrent thrombo-embolic problems. The patient's father had died following a thrombo-embolic disorder. A certain number of members of the family also showed evidence of a marked decrease in AT III levels. Although it was not possible to study the patient's parents, it would seem reasonable to conclude that the diagnosis was one of hereditary deficiency in AT III. The various aspects of this disorder discovered by Egeberg are reviewed: early onset, in several members of the same family, or recurrent thrombo-embolic problems, accompanied by a decrease in functional activity of one of the principal inhibitors of thrombin (AT III), with autosomal dominant transmission and treatment based upon anti-vitamin K agents.

Adult↗

["Immuno-allergic" complications of rifampicin therapy].

From 8 cases of immuno-allergic accidents attributed to Rifampicine, the authors review the literature on the subject. The "flue like" syndrome is the most frequent and characteristic of those accidents, worsened by haematological and renal involvements. These accidents probably belong to a pathology of immuno-complexes in relaiton with the production of anti-Rifampicine antibodies. Among the different means of in vitro diagnosis, the test with the anti-complement antiglobulin is the most reliable, though not always in good correlation with clinical signs. Though rare and most often benign, these accidents should lead to prudence in treating recurrent tuberculosis or reusing Rifampicine after a momentary interruption.

Aged↗

[Alveolar microlithiasis (apropos of a case)].

One new case of alveolar microlithiasis is reported on that includes, besides the radio-clinical investigations, complete functional exploratory studies and anatomic authentications. Authors recall the diagnostical procedures and our present ignorance of the pathogenesis of this curious entity; no valid therapy is presently able to check the relentless course towards progressive respiratory deficiency.

Adolescent↗

[Evaluation of the frequency of asthma among the adolescents attending school in the Bas-Rhin (author's transl)].

The frequency of asthma in a population including all the adolescents attending school in the department of Bas-Rhin (29 138) in May and June 1976, is 4,1%. This rate is 4,9% in boys and 3,4% in girls. The frequency of asthma is higher in urban areas (5,0%) than in rural areas (3,8%). Asthma is related to respiratory symptoms and is related to more school absenteeism (26%) than in non asthmatics (13,7%). These findings are confirmed by the data given in other medical surveys.

Absenteeism↗