Search PubMed⌕ Search

Biomedical subjects

G Bouchard

Publications and source records attributed to G Bouchard.

69 records · Page 4Linked to original sources
PubMed1976

Basic targets and the different epilepsies.

The follow up of 49 stereotactically operated epileptics is graphically demonstrated and the 79 operations in basic targets within the amygdala and the area of the anterior pole of the thalamus are described. The patients had valuable gaining in 80%; The continued developement of stereotactic methods in the future is urgent, so long as 30% of the epileptics respond poorly to drug therapy and only 5-10% are suitable to the traditional resection methods.

Adolescent↗
PubMed1976

Thalamic evoked potentials to somatosensory stimulation in man.

Thalamic somatosensory evoked potentials (ThSEPs) were recorded by averaging technique from various thalamic structures during 59 stereotactic operations. From 372 records, response patterns and latency characteristics were analysed in relation to the intrathalamic localization. The findings can be summarized as follows. In N. ventro-caudalis (VC) and ventro caudalis parvocellularis (Vcpc) ThSEPs showed the most definite (and exclusively contralateral) responses characterized by a single positive (P1) deflection. The latency was shortest in VC (mean value, 17.5 msec) and in Vcpc (15.6 msec). Responses from N. centrum medianum (CM), parafascicularis (Pf) and limitans (Lim) were composed of early P1-N1 and of later P2-N2 components. The P1 latency was relatively consistent, with a mean value of 28.2 msec. Pulvinar responses showed a pattern similar to CM, with a mean P1 latency at 30.5 msec. Responses of N. dorsalis medialis (DM) were small, variable and longest, with a mean P1 latency of 54.2 msec. To ipsilateral stimulation, CM, Pul, DM and N. ventro-lateralis (VL) showed comparable wave forms. The possible role of the CM-Pf-Lim complex and of Pulvinar in the "extra-lemniscal" sensory system was considered. The usefulness of ThSEP recording to identify electrode locations in the thalamus is thus confirmed.

Adult↗
PubMedDate not supplied

Evaluation of stereotactic thalamotomies for pain relief with reference to pulvinar intervention.

Stereotactic thalamotomies were carried out in 51 cases of malignant and 9 cases of other painful conditions. The patients were divided into two groups--those with a relatively small lesion created in the basal part of the CM nucleus and those with a larger lesion extending into the pulvinar. In total, 50% of the cases showed complete pain relief, 20% partial relief and 30% no effect. The group with pulvinar intervention showed better results, especially those with malignancies.

Follow-Up Studies↗
PubMedDate not supplied

[From micro- to macro-reconstitution of families: the SOREP system].

"This article outlines a new system for computerized family reconstitution. It has been developed in the last ten years by a multidisciplinary team of Quebec researchers belonging to the inter-university research center on populations (SOREP). Basically, this system is characterized by: a) an attempt to computerize as much as possible every step involved in the process of reconstitution, b) a set of tools devised for identifying and measuring all forms and degrees of similarity between names and surnames, c) a technique to process cases of ambiguous links, d) a set of programs used to assess the quality of the data and the strength of the links created, [and] e) an attempt to maximize the performance of the linkage work in terms of both efficiency and accuracy. The system has been designed to support several kinds of analyses, from social history and demography to population genetics. Our paper contains a brief overview of the current state of research in the field of record linkage, an introduction to the Saguenay [Canada] population register and a description of the system itself which has been utilized successfully in the last year on the 660,000 Saguenay parish records, covering the period 1842-1971." (SUMMARY IN ENG AND ITA)

Americas↗
PubMedDate not supplied

[Computerized family reconstitution on a large data-base: the SOREP system].

This article outlines a new system for computerized family reconstitution. It has been developed in the last 10 years by a multidisciplinary team of Quebec researchers belonging to the Inter-University Research Center on Populations (SOREP). Basically, this system is characterized by 1) an attempt to computerize as much as possible every step involved in the process of reconstitution, 2) a set of tools devised for identifying and measuring all forms and degrees of similarity between names and surnames, 3) a technique to process cases of ambiguous links, 4) a set of programs used to assess the quality of the data and the strength of the links created, and 5) an attempt to maximize the performance of the linkage work in terms of both efficiency and accuracy. The system has been designed to support several kinds of analyses, from social history and demography to population genetics. The paper contains a brief overview of the current state of research in the field record linkage, an introduction to the Saguenay population register, and a description of the system itself which has utilized sucessfully in the last year on the 660,000 Saguenay parish records, covering the period 1842-1971.

Americas↗
PubMedDate not supplied

[The reproduction of families affected by Steinert's dystrophy in Saguenay (Quebec), 1885-1971: demographic parameters].

"In the light of the literature in the field, one would expect that the myotonic dystrophy (or Steinert) gene carries a severe selective disadvantage. Indeed, this phenotype is commonly said to entail...sterility, infant mortality, and a lower nuptiality. In the worst cases, it is not unlikely that the gene could eliminate itself through non-reproduction. [A model is developed and] tested in the Saguenay (Quebec) population, known for its exceptionally high prevelance (1/475) of the disease. Authors have been able to use a computerized demographic and genealogical data base in order to study several demographic variables (fertility, nuptiality, mortality, etc)....Case-control analyses produced very [few] differences between affected and control families, suggesting no significant selective disadvantage associated with the gene." (SUMMARY IN ENG AND ITA)

Americas↗