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Biomedical subjects

G Boschi

Publications and source records attributed to G Boschi.

41 records · Page 3Linked to original sources
PubMedDate not supplied

[Structural modifications and hematic variations in pregnant and/or suckling rats kept on a purified diet with high content of animal proteins].

The effects of a high protein diet (casein 40%, lactalbumin 20%) were evaluated in pregnant and/or suckling rats. Histological studies of the organs showed structural alterations to the liver, adrenal cortex, kidneys and heart accompanied by significant metabolic changes in blood glucose and triglyceride levels. Overall the experimental results encourage the belief excessive intake of animal protein, particularly at an early stage, may do specific damage to the normal course of pregnancies, given the low birth rate and high incidence of perinatal mortality observed in the offspring produced by mothers given high protein diets throughout pregnancy.

Adrenal Cortex↗
PubMedDate not supplied

[Values of a number of blood parameters and body growth of rats subjected to fetal and post-natal protein malnutrition].

Nests of rats, generated by mothers receiving synthetic diets of different protein content during gestation and in post-pregnancy phase, have been kept under observation during suckling and after weaning care being taken that offspring received the same diet as characterised maternal feeding. It was found that in the animals receiving hypoproteic diet (6% proteins), early induced malnutrition extended up to the 40th day of life, namely the term for the cellular subdivision of almost all organs, cuts body growth by about 80% compared to control rats, and is accompanied by a remarkable drop in packed-cell volume and haemoglobin value. In parallel, the electrophoretic pictures of hypoproteic rats were characterised by a drop in serous albumin, offset by a marked rise in beta and gamma globulin, Finally, evaluation of the weigh ratios between the brain and other organs of vital importance, underlines the preferential growth of the cerebral mass in rats receiving an inadequate protein supply.

Animals↗
PubMedDate not supplied

[Urban air pollutant exposure among traffic policemen].

Exposure to dusts and benzene was studied in 65 traffic policemen. Samples of total dusts showed that mean personal exposure was 0.44 (SD = 0.30) mg/m3, with peaks of about 2 mg/m3. Exposure to 1-nitropyrene (1-NP), the main compound occurring in emissions from diesel engines, which was estimated from concentrations in dusts collected with high-flow samplers, was 0.28 (SD = 0.19) ng/m3 (range: 0.06-1.24 ng/m3). The mean concentration of benzene in the breathing zone was 41 (SD = 20) micrograms/m3, although a level of 100 micrograms/m3 was slightly exceeded in one subject. In urine samples collected before and after workshifts, two biological indicators of exposure to benzene were measured, urinary benzene and urinary trans, trans-muconic acid (MA). The mean values of urinary benzene before and after workshift were similar (98, SD = 81 and 83, SD = 55 ng/l; n = 63; Wilcoxon's T-test = not significant), while a moderate increase in the metabolite was observed (MA = 0.08, SD = 0.11; 0.11, SD = 0.09 mg/g creatinine, in pre- and post-shift samples respectively; Wilcoxon's T-test, z = 3.00; p < 0.01). The levels of exposure to dusts and 1-NP deriving from diesel engine emissions were comparable to those of other occupational groups with this type of risk (garage mechanics, workers operating diesel engine machinery, etc.). Traffic police exposure to benzene was similar to that of the whole population of Padova (40 micrograms/m3, mean annual 24-hour value). However, the values of urinary MA, like those reported by other authors for non-smoker controls, increased after the workshift, indicating low occupational exposure to this pollutant. It should be noted that traffic police exposure to benzene is much lower than that of other occupational categories, e.g., fuel pump distributors.

Air Pollutants↗