Search PubMed⌕ Search

Biomedical subjects

G Boner

Publications and source records attributed to G Boner.

At least 109 records · Page 6Linked to original sources
PubMed1985

Kidney transplantation in patients on continuous ambulatory peritoneal dialysis.

In the 45 months from April 1980 to December 1983, 137 patients received first cadaver kidney grafts. Thirty-two of the patients were on continuous ambulatory peritoneal dialysis (CAPD group) and 105 were on haemodialysis (HD group). The two groups of patients were similar in respect to pre-transplant blood transfusions, mean age, HLA-A, B, DR matching and immunosuppressive therapy. In 14 CAPD patients at least one episode of peritonitis was documented before transplantation. The actuarial graft and patient survival was 57 per cent and 84.4 per cent, respectively for the CAPD group and 55.8 per cent and 85.3 per cent in the HD group. No patient in either group had evidence of peritonitis after the transplantation. These similar results indicate that kidney transplantation in CAPD patients carries no greater risk than in patients on haemodialysis.

Adolescent↗
PubMed1985

Deterioration in renal function in patients with chronic renal failure after treatment with captopril.

Acute reversible renal failure has been reported in patients receiving captopril, especially those with unilateral or bilateral renal artery stenosis. Two patients with advanced renal disease presented with an acute deterioration in renal function after the introduction of captopril treatment. In both instances this deterioration was irreversible. Captopril should be used with caution in patients with advanced renal disease.

Aged↗
PubMed1985

Intestinal incarceration in occult abdominal wall herniae in continuous ambulatory peritoneal dialysis.

Herniae are a common complication of treatment with continuous ambulatory peritoneal dialysis (CAPD). The diagnosis is often difficult because the hernia may not be apparent, or because the symptoms may mimic peritonitis or other severe abdominal complications. This report describes the occurrence of intestinal incarceration in an occult incisional hernia in two CAPD patients. The possibility of this diagnosis must be considered in CAPD patients complaining of severe abdominal pain.

Aged↗
PubMed1984

Serum angiotensin converting enzyme activity in normal adults and patients with different types of hypertension.

The serum converting enzyme activity (SCEA) was measured in 86 healthy individuals (1.44 +/- 0.82 u, mean +/- SD), 39 patients with essential hypertension (1.53 +/- 0.71 u), 7 patients with hypertension due to renal artery stenosis (1.76 +/- 0.77 u), 14 patients with chronic renal failure (2.10 +/- 0.57 u), 7 patients with renal failure and hypertension (2.62 +/- 0.35 u), 22 normotensive pregnant women (1.02 +/- 0.26 u) and 6 hypertensive pregnant women (1.1 +/- 0.3). No difference was detected between men and women or between normotensives and hypertensives. However, a significant rise in SCEA was found in patients with chromic renal failure (P less than 0.005), in whom an enlarged pulmonary vascular bed and accelerated cellular breakdown are thought to be the causes of the elevated SCEA. During pregnancy, subnormal SCEA was found (P less than 0.005), and this is thought to be due to the enzyme consumption in the kinin system, which is activated during pregnancy. We assume that converting enzyme is not a limiting factor in angiotensin conversion, and most probably it does not contribute significantly to the pathogenesis of hypertension.

Adult↗
PubMed1984

Massive proteinuria in patients with chronic pyelonephritis.

Massive proteinuria associated with chronic pyelonephritis is reported in five patients. Two of them were known to have vesicoureteral reflux, whereas three had minor predisposing factors only. None of the patients were in severe renal failure or suffered from severe hypertension at the time of massive proteinuria. Results of histological examinations were compatible with a diagnosis of chronic pyelonephritis. Electron microscopy and immunological studies did not show any primary glomerular lesions.

Adult↗
PubMed1983

The clinicopathologic features of cryoglobulinemic nephropathy.

Renal biopsy specimens from eight patients with cryoglobulinemic nephropathy were examined by light, electron, and immunofluorescence microscopy. The light microscopic features were not diagnostic. Characteristic ultrastructural findings were observed in all except one specimen and consisted of glomerular electron-dense deposits, which had a coarse, granular appearance at low-power magnifications and revealed tubular, annular and in a few cases, also fibrillar structures at high-power magnifications. Subendothelial deposits were a constant finding. The presence of intravascular thrombi (deposits), osmiophilic bodies, and crystals within the cytoplasm of the glomerular cells are also helpful for the diagnosis of this entity. Because of these specific findings, cryoglobulinemic nephropathy should be recognized as a clinicopathologic entity.

Adolescent↗
PubMed1983

Effect of continuous ambulatory peritoneal dialysis on anemia in uremic patients.

The effect of continuous ambulatory peritoneal dialysis (CAPD) on anemia was examined in 10 patients over a period of 6 mo. The mean hemoglobin levels in these patients did not change during this period and were not different from those of a group of 10 patients on hemodialysis. There were no changes in serum iron, iron saturation, serum haptoglobin, serum parathyroid hormone and red cell survival during this period. There was an inverse correlation between serum ferritin and hemoglobin levels. These studies show that CAPD is not associated with an improvement in anemia of uremic patients. Previous report on improvement in anemia most likely reflected the smaller loss of blood during CAPD compared with hemodialysis.

Adult↗
PubMed1983

Renal osteodystrophy in end-stage renal failure patients in Israel.

Renal osteodystrophy is one of the major complications in patients on long-term hemodialysis. A group of 42 patients on hemodialysis (mean age 42 yr) were investigated in order to assess the prevalence of renal osteodystrophy in Israeli patients. The patients were examined by X-ray, and 66.7% were found to have signs of osteodystrophy. Of 14 patients without signs of bone involvement, 10 had been on treatment less than 1 yr. A bone biopsy, performed in 28 patients (mean age 43 yr), showed signs of renal osteodystrophy in all. Two of these patients were diagnosed as having mainly osteitis fibrosa, four as having osteomalacia and the rest as having the symptoms of both.

Adult↗
PubMed1982

Macrophage migration inhibitory activity in the sera of patients undergoing peritoneal dialysis for psoriasis.

A study of macrophage migration inhibitory activity (MIA) in serum was carried out in four psoriatic patients with normal renal function who were undergoing peritoneal dialysis (PD) as a method of therapy. Before weekly PD treatment, the MIA was negative in these patients. whereas immediately thereafter it was positive. In two of these patients the appearance of MIA paralleled the clinical improvement observed. The increase in MIA observed after each PD was of short duration, usually being followed by a subsequent decrease prior to the next PD. Seven uremic patients who were similarly studied for the presence of MIA before and after PD did not show this pattern of response. It is suggested that the appearance of MIA in psoriatic patients undergoing PD as a method of therapy reflects the extraction of a "dialysable serum factor", which may be associated with cell-mediated immunity as well as with the clearing of skin lesions observed in these patients.

Adult↗
PubMed1982

Effects of pindolol on renal function II. Effects on intravenous and prolonged oral dosing.

Effects of intravenous and long-term oral dosing with pindolol on renal function were examined in eight hypertensive patients with reduced renal function. (Inulin clearance ranged from 40.5 to 84.5 ml/min/1.73 m2.) Intravenous pindolol resulted in decreased mean heart rate (74.3 to 67 bpm) and decreased mean inulin clearance (66 to 60.5 ml/min/1.73 m2.) Blood pressure and renal plasma flow did not change significantly. Long-term oral pindolol depressed blood pressure and heart rate, but mean inulin clearance was unchanged and renal blood flow and plasma volume increased. A second intravenous pindolol dose, given while the patients were receiving oral doses, resulted in nonsignificant decreases in glomerular filtration rate and renal plasma flow, but no change in blood pressure and heart rate. We conclude that prolonged pindolol dosing in patients with reduced renal function had no effect on renal function. When the drug was given intravenously there were small decreases in glomerular filtration rate and renal plasma flow.

Administration, Oral↗
PubMed1982

Renal function during acute and long term pindolol treatment in hypertensive patients with normal and decreased glomerular filtration.

1 In an acute study in hypertensive patients with normal and decreased renal function the i.v. administration of pindolol (0.1 mg/kg) caused a decrease in inulin clearance and a concomitant but not significant decrease in PAH clearance with a constant filtration fraction. 2 The long-term administration of pindolol (5--20 mg/day) to hypertensive patients with normal renal function was not associated with changes in renal function but in patients with a decreased renal function, pindolol caused an increase in PAH clearance but no change in inulin clearance.

Administration, Oral↗
PubMed1982

Spontaneous rupture of the kidney in a patient with acute autoimmune disease.

A percutaneous renal biopsy was performed on a 50-year-old female with rapidly progressive renal failure. The histologic specimen was characteristic of an immune complex disease, most likely systemic lupus erythematosus. Serologic tests were negative. 8 days after the biopsy, there was a spontaneous rupture of the kidney which necessitated nephrectomy. As no connection was found between the biopsy site and the rupture, it was concluded that the rupture was spontaneous in a patient with an immune complex disease.

Female↗