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Biomedical subjects

G Blanc

Publications and source records attributed to G Blanc.

104 records · Page 6Linked to original sources
PubMed1956

[Toxoplasmosis].

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Toxoplasmosis↗
PubMedDate not supplied

[Coronary stenoses and surgical possibilities according to the coronarographic indication. Evaluation of 1000 studies].

The degree of severity of coronary artery lesions and the quality of the distal vessels which justify revascularisation by by-pass grafting were studied in 1,000 consecutive cases of coronary angiography. The results are presented in terms of the clinical indication for coronary angiography and in terms of the patients' age and sex. 47% of patients were investigated because of unstable angina and 53% of them had surgical lesions. 16% of the angiographies were performed three weeks after myocardial necrosis. 45% of these patients had a surgical lesion in a coronary territory other than that of the necrotic area. In 20% of cases, the coronary angiography was performed as part of the pre-operative work-up for valvular heart disease. 17% of these operations combined a by-pass graft with the valve replacement. Independent of the indication for coronary angiography, 20% of cases had major coronary artery stenoses which reduced the lumen by more than 70% and which were inoperable.

Constriction, Pathologic↗
PubMedDate not supplied

[Sevoflurane].

Sevoflurane is a fluoridated derivative of methyl isopropyl ether. Its administration does not require the use of sophisticated vaporizers and its blood/gas partition coefficient is 0.69. Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled induction. It offers a high level of precision in the control of deep anesthesia during maintenance, recovery is rapid, and MAC is 2%. Sevoflurane seems to be the pediatric anesthetic of choice and it is also highly useful for anesthesia in ambulatory patients. Sevoflurane gives rise to hemodynamic stability, is not arrhythmogenic, and does not sensitize the myocardium to the effects of catecholamines. The effects on cerebral blood flow are minimal at low concentrations. Metabolism is 3-4%. Renal toxicity has not been reported even though fluoride is a metabolic product. Sevoflurane breaks down in the presence of soda lime, producing compound A and giving rise to controversy and investigation although the toxicity of compound A is more theoretical than real. Sevoflurane is not harmful to the ozone layer.

Anesthetics, Inhalation↗