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Biomedical subjects

G Benoit

Publications and source records attributed to G Benoit.

At least 217 records · Page 12Linked to original sources
PubMed1987

[The anatomy of erection].

The authors review the current knowledge concerning the anatomy of erection. The nervi erigentes pass through the hypogastric plexus, travel along the cavernous nerve and terminate in the smooth muscle of the erectile bodies. There appears to be three types of nerves: adrenergic nerves, cholinergic nerves and non-adrenergic, noncholinergic nerves. The arterial blood supply is derived from branches of the internal pudendal artery. The venous drainage occurs via the circumflex veins towards the deep dorsal vein of the penis. The corpus cavernosum is composed of a thick, extensible albuginea which contains an extensible vascular network surrounded by smooth muscle tissue, which, when it contracts, appears to induce detumescence and, when it relaxes, appears to allow inflow of blood into the erectile bodies.

Humans↗
PubMed1987

[Intravenous digital angiography in the kidney transplant patient: results of a systematic prospective study in 164 patients].

A prospective study on digital intravenous angiography (DIVA) in 164 renal transplant recipients performed from 1 to 2 months post-transplant was conducted to assess its usefulness in the screening of post-transplant renal artery stenosis (RAS). DIVA was uninterpretable in 32 patients (19%) on technical grounds (blood vessel or metallic clip superimposed). The global prevalence of RAS was 10.7% in 132 patients whose DIVA was informative. No correlation was found between the prevalence of RAS and renal function. The prevalence of RAS was significantly higher (p less than 0.01) in the hypertensive (26%) than in the normotensive group (6.6%), but RAS may occur in normotensive or even asymptomatic patients. Our data confirm the usefulness of routine post-transplant renal artery screening but arterial way will be preferred.

Adult↗
PubMed1987

[Expression of blood group antigens in 30 patients with transitional-cell carcinomas of the bladder].

From the follow up of 30 patients whose bladder tumours were repeatedly resected over a period ranging from several months to 18 years, we carried out a study of AGS Antigen expression using an A B O histokit. We were able to establish that this histokit is reliable and very easy to use. We also observed in the urothelial tumours a modification in AGS expression tending towards frequent loss. The AGS staining coincides with the grade of the tumour. Tumours totally stained are always of low grade. However, in this short group of patients, we were unable to draw any interesting correlation between the immunological profile and the clinical course of the transitional bladder carcinomas. In the case of patients with superficial tumours whose histological aspect and clinical course are comparable, the immunological aspect differs. It must be emphasised that in subsequent studies necessary to establish the prognosis of bladder tumours the A B O histokit is easy to use in conjunction with the histological study.

ABO Blood-Group System↗
PubMed1986

[Urologic complications of renal transplantation. Role of the length of the ureter].

Four hundred and thirty renal transplantations have been performed over a 5-year period during which there was a switch of surgical technique towards uretero-vesical anastomosis. In this paper, the urological complications observed are studied according to the site of transplantation, the position of the kidney, the type of anastomosis and the length of the ureter. Kidneys that were transplanted in iliac position gave rise to more complications than those transplanted in pelvic position, and reversing the kidney increased the number of urological complications. The complication rate was 6.7% with the uretero-vesical anastomosis and 12% with the uretero-ureteral anastomosis. The best results were obtained when the kidney was transplanted into the iliac fossa in pelvic position with its upper pole upward and its ureter anastomosed with the bladder: in 274 transplantations performed with this technique the complication rate was 4.7%. This study of different types of transplantation shows that the main factor is the ureteral length utilized: the longer that segment of the ureter, the more numerous the urological complications.

Constriction, Pathologic↗
PubMed1986

[Anatomical study of the verumontanum of the urethra].

Five samples of infra-montanal prostatic urethra, fixed in formalin and stored in liquid nitrogen at -30 degrees C were examined histologically. The results of this study demonstrated that muscle fibres of the striated sphincter extend as far as the level of the veru montanum. The proportion of rapid and slow striated fibres was identical. These striated fibres were mixed with smooth muscle fibres of the urethra. The density of innervation of this muscular tunic was found to increase closer to the striated sphincter; it is composed of equal numbers of adrenergic and cholinergic fibres.

Humans↗
PubMed1986

[Ureteral metastasis of a prostatic cancer].

The authors report the case of a patient treated medically for prostatic cancer, who presented with a ureteric metastasis suggestive of a tumour of the excretory tract. Histological examination revealed that this lesion was actually a suspended metastasis of prostatic cancer.

Adenocarcinoma↗
PubMed1985

[Prospective study of a triple immunosuppressive combination in renal transplantation: cyclosporin A-corticoids-azathioprine].

Cyclosporin A significantly improves patient and graft survival as compared with the conventional corticosteroid-azathioprine treatment. However, the results are the same, or even worse, when the cyclosporin A-corticosteroid regimen is compared with the corticosteroid-azathioprine-antilymphocyte globulin regimen. The authors have investigated a prednisone-azathioprine-low dose cyclosporin A combination in 46 high risk patients from a series of 117 renal transplantations performed in 1983. The actuarial patient and graft survival rates were as good as, but not better than, those obtained in 1982 in 106 patients treated with the conventional regimen which includes antilymphocyte globulin; they were 96.5% vs 98% and 85.5% vs 84% respectively at 6 months; 96.5% vs 98% and 83.5% vs 84% respectively at 12 months. The low dosage utilized (8 mg/kg instead of the usual 14-17 mg/kg) avoided virtually all the extrarenal side-effects of cyclosporin A, but not its nephrotoxicity. The theoretical risk of excessive immunosuppression was not confirmed by our study. Since cyclosporin A is very expensive, other therapeutic methods for optimal usage of that drug should be investigated.

Azathioprine↗
PubMed1985

[Continuous ambulatory peritoneal dialysis before renal transplantation].

In order to evaluate precisely the place of continuous ambulatory peritoneal dialysis in the treatment of chronic renal failure, it is important to find out whether this method may produce complications, mostly infectious, after renal transplantation. From April, 1979 to December, 1983, 419 renal transplantations were performed in our centre; 17 of these patients had previously been treated with peritoneal dialysis over a mean 13.5 months period, with 3.2 peritonitis/patient. The peritoneal catheter was left in situ for 4 to 16 weeks post-graft, so that the patients could easily be dialysed if needed; it was removed during transplantation in the only 3 cases of recent peritonitis. The only complications noted after transplantation were an episode of spontaneously reversible ascites and a peritoneal breach following reintervention on the renal region. This homogeneous series confirms that continuous ambulatory peritoneal dialysis does not constitute a contra-indication, let alone an obstacle, to subsequent renal transplantation. Indeed, it may be regarded as the first-choice method for patients in whom early grafting is envisaged on account of their immune status.

Adult↗