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Biomedical subjects

G Arvis

Publications and source records attributed to G Arvis.

At least 55 records · Page 3Linked to original sources

[Calcium oxalate monohydrate (whewellite) renal lithiasis].

Pure calcium oxalate monohydrate lithiasis is rare--about 5 to 10% of total renal lithiases. The proportion is the same in men and women. Pure calcium oxalate stones are a polished dark brown color, and are very hard. They are visualized radiologically as regular and homogeneous. From a biological standpoint, this type of stone is frequently associated with normal calciuria and oxaluria. Pure calcium oxalate monohydrate stones rarely evolve.

Adult↗

[Calcium oxalate stones and hyperoxaluria secondary to treatment with pyridoxilate].

Pyridoxilate is a salt formed from glyoxylic acid and pyridoxine. It has been used therapeutically as an antianoxic drug in the treatment of various arterial complaints. Its use is based theoretically on its ability to block the conversion of glyoxylic acid into oxalic acid. The following cases suggest, however, that pyridoxilate can cause stones. Intraperitoneal injection of glyoxylate in doses of 130 mg/kg will cause oxalate stones in rats. The same effect results from injection of 427 mg/kg pyridoxilate (i.e. an equivalent dose of glyoxylate). In human subjects, intravenous injection of 200 mg of pyridoxilate results in a fourfold increase in the urinary oxalic acid content in the two hours following the injection. Thirteen cases of chronic progressive oxalate stone disease have recently been reported in patients receiving a prolonged course of pyridoxilate at 450 to 600 mg daily. Eight of these patients had no previous history of lithiasis. Oxaluria levels of 80 to 100 mg daily are observed in all cases of lithiasis in patients receiving pyridoxilate. The levels fell after cessation of the pyridoxilate treatment, and reverted to normal (30 mg/24 hours) in all but three patients. These three patients maintained levels of close to 50 mg and all three had a previous history of urolithiasis.

Aged↗

[Treatment of recurrent urogenital infections by immunomodulation].

In recurrent urogenital infections in which no curable cause can be found, long term antibiotic therapy is often the only possible form of treatment. After performing appropriate skin tests, the authors evaluated the effectiveness of vaccination consisting of antigen therapy and an immunostimulant, P 40, in 20 patients. The recurrent infections were controlled in the cases in which this combination was used; in half of the cases, maintenance vaccination was required for a period of 2 or 3 years.

Adjuvants, Immunologic↗

[Urethral stricture: one-stage urethroplasty using a free skin flap].

We report our experience of one-stage free skin graft urethroplasty in 18 patients, most of whom had iatrogenic stricture of the urethral bulb. Our results were similar to those reported in the literature, being satisfactory in about 80% of the cases, and were further improved by adjuvant procedures, such as urethrotomy. We consider that free skin graft urethroplasty is the most reliable method to treat strictures of the urethral bulb after failure of urethrotomy.

Adult↗

[1-step urethroplasty using Devine's technic. Its use in 18 cases of urethral stricture].

A one stage procedure using a free patch graft of skin for correcting of the urethral strictures was executed in 18 patients. In our series the strictures were mainly located in the region of the bulbar urethra. Good results have been obtained in 14 (80%) of 18 cases with a follow up of up to two years. It is a simple and effective method of treatment. It has given us a more consistent satisfactory result than any other methods described until now. The good results obtained by us with this method results substantiated by the other series, we advocate this on stage urethroplasty for repair of selected bulbar urethral strictures.

Adult↗

[Monohydrate and dihydrate oxalic lithiasis. Calculi, their macroscopic structure (radiographic and therapeutic impact). Calciuria and oxaluria].

Calculi of pure calcium oxalate monohydroxide are hard, polish, dark brown stones, of a very tenuous crystalline structure. On the contrary, calculi of pure bihydroxide oxalate are clear irregular stones with a spiky surface. They are more friable and less hard than monohydroxide oxalate stones. Monohydroxide oxalate stones radiologically are regular and homogeneous, whereas bihydroxide oxalate stones have an irregular aspect. Monohydroxide oxalic lithiasis is less frequent than bihydroxide oxalic lithiasis. The proportion of monohydroxide lithiasis is the same in men and women whereas bihydroxide lithiasis is more frequent in men. Of a biologic point of view, in monohydroxide lithiasis, calciuria and oxaluria are often normal while proportion of hypercalciuria and hyperoxaluria is more important in bihydroxide lithiasis. Evolutivity is clearly inferior in monohydroxide lithiasis than in bihydroxide lithiasis.

Adult↗

[Drainage of the bladder by suprapubic catheterization (author's transl)].

In most cases of urine retention due to lower urinary tract obstruction, the distended bladder can be drained by suprapubic catheterization. Only large intervesical blood clots cannot be removed by this method. The technique has been simplified and made non-traumatic and safe by the advent of small-diameter, self-winding, polyrethane catheters (Cystofix) which are easy to handle and well tolerated. The urethra and possible cervico-prostatis obstacles are left undisturbed, and radiological as well as manometric explorations can be performed. Complications do not occur if bladder distention is well ascertained, if the catheter is accurately inserted and if stringent aseptic precautions are taken. In the authors' unit suprapubic catheterization has become common practice and transurethral catheterization is seldom performed.

Humans↗

[Immunofluorescence study of bacteriuria. A new technic for the localization of urinary infection].

The detection by immunofluorescence of immunoglobulins fixed to the wall of urinary bacteria makes it possible to localise the site of the urinary infection. The presence of immunoglobulins was noted in 18 out of 19 patients with a high urinary tract infection involving the renal parenchyma. They were absent in 25 out of 28 subjects with a lower urinary tract infection. The three apparently discordant positive reaction involved 1 case of prostatitis and two cases in which the diagnosis of pyelonephritis was made later. In the case of renal involvement, these immunoglobulins, essentially IgG, are seen with greater frequency than humoral antibodies. Whilst the biological significance of these immunoglobulins remains uncertain, their existence probably being a reflection of parenchymatous inflammation, this nevertheless is a new and, apparently, reliable, method for the determination of the site of an infective process.

Adult↗