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Biomedical subjects

G Adams

Publications and source records attributed to G Adams.

At least 163 records · Page 9Linked to original sources

Complicated mandibular fractures.

In many mandibular fractures, proper alignment of the fragments is only a portion of the management program. Consideration must be given to the possibility of numerous other complications, and the patient should be carefully evaluated for injuries of the cervical spine, skull, head, and chest. The medical background, age, and other factors, such as the patient's ability to cooperate and follow the physician's instructions, may determine the method of applied treatment.

Adolescent↗

Simple and rapid preparation of granulocytes for the treatment of neonatal septicemia.

Recent reports have documented benefit from the infusion of granulocytes into septic neonatal patients. However, while the requirement of 1 X 10(9) per kg of granulocytes is easily met by apheresis procedures, treatment of neonatal septicemia requires immediate response 24 hours a day. Unfortunately, this rapid response is beyond the capability of most apheresis units. Therefore, we developed a method for obtaining granulocytes from whole blood collected by routine blood donation. Hydroxyethyl starch (60 ml of a 6% solution) is introduced into a unit of whole blood within 24 hours of collection. Following sedimentation and subsequent centrifugation, a buffy coat is obtained which contains more than 75 percent of the granulocytes; an average of 1.62 X 10(9) WBC, of which 1.25 X 10(9) were granulocytes that were recovered in an average 17-ml final volume with a hematocrit of 4 percent. Granulocyte morphology and function as measured by chemiluminescence indicated good maintenance of function. Total processing time was short, requiring less than 2 hours, and the procedure was performed easily in a routine blood bank. The recovery of 1.25 X 10(9) granulocytes from a single, routine blood donation without steroid treatment of the donor makes this product ideal for use in the treatment of neonatal septicemia.

Cell Separation↗

Pneumothorax as a complication of tracheoesophageal voice prosthesis use.

A previously unreported association of pneumothorax and the use of a tracheoesophageal voice prosthesis is presented. A review of 44 cases revealed that two patients developed a pneumothorax requiring chest tube placement. Pulmonary barotrauma is believed to be the cause of the injury. In those patients in whom the tracheoesophageal voice prosthesis has been effective, it has produced excellent results. However, certain pulmonary conditions may be considered a relative contraindication to the use of the tracheoesophageal voice prosthesis in patients who must generate significant force to produce voice. Patients using a voice prosthesis who present with symptoms of chest pain or dyspnea must be evaluated carefully for pulmonary rupture.

Barotrauma↗

Fluid and electrolyte replacement in the ultramarathon runner.

We studied three male runners during three separate ultramarathon races. Serial blood samples were tested for electrolytes, renal function, albumin, calcium, phosphorus, and magnesium. Two runners had aldosterone levels measured during the race and one runner had blood lactate levels measured. All runners ingested an isotonic fluid and electrolyte solution during the race. The runners consumed the solution without medical complications and maintained prerace body weights and hydration levels. Each runner maintained normal endocrine/metabolic parameters. We concluded that it is possible to maintain normal hydration and electrolyte states during a prolonged race, provided that sufficient fluid and electrolyte solutions are ingested.

Adult↗

Urban hospital's innovations save money, win support.

Lutheran Medical Center (LMC) was a failing hospital in a depressed Brooklyn neighborhood until administrators and board members reassessed their purpose and goals. Now LMC is a community-oriented organization that offers acute hospital care for an urban population in excess of 350,000 people, provides cost-effective healthcare to more than 50,000 ambulatory patients a year, and has helped to revitalize its neighborhood. LMC's surprising range of accomplishments and activities include the following: Providing staff members to serve as resources and support staff for community groups; Organizing a neighborhood redevelopment committee, obtaining and administering grants, providing office space, and acting in an advisory capacity until the committee was able to separately incorporate; Creating an educational program for undereducated and underemployed area residents; Establishing a school health program to handle unmet routine healthcare needs of area children; Renovating an abandoned factory on the worst block in the community and relocating the hospital to that site; Founding the country's largest federally supported neighborhood health center; Signing a contract with New York state to provide healthcare for 10 percent less than the average cost of care for Medicaid patients.

Community Health Centers↗

Child care and our youngest children.

Studies of child development confirm that experiences with people mold an infant's mind and personality. Caregiving is, therefore, central to development, whether the caregiver is a parent, a grandmother, or a teacher in a child care center. This article uses data from new, national studies of families to examine the state of child care for infants and toddlers. The story it tells is complex, as the authors outline the overlapping impacts that diverse child care settings and home situations have on children. Early exposure to child care can foster children's learning and enhance their lives, or it can leave them at risk for troubled relationships. The outcome that results depends largely on the quality of the child care setting. Responsive caregivers who surround children with language, warmth, and chances to learn are the key to good outcomes. Other quality attributes (like training and staff-to-child ratios) matter because they foster positive caregiving. Diversity and variability are hallmarks of the American child care supply. Both "wonderful and woeful" care can be found in all types of child care but, overall, settings where quality is compromised are distressingly common. Children whose families are not buoyed by good incomes or government supports are the group most often exposed to poor-quality care. Given this balanced but troubling look at the status of child care for infants and toddlers, the authors conclude that there is a mismatch between the rhetoric of parental choice and the realities facing parents of young children in the United States. They call on communities, businesses, foundations, and government to play a larger role in helping parents secure good care for their infants and toddlers.

Child Care↗