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Biomedical subjects

F X Carton

Publications and source records attributed to F X Carton.

At least 19 recordsLinked to original sources

[Acquired cutaneous osteomatosis. A primary monomelic form].

Eight cases of sporadic acquired primary osteoma cutis have been reported in the literature. Age at onset varies from 16 to 55 years with a mean of about 35 years. The sex ratio is 1 and a wide range of localizations have been reported. There is no known treatment. We report a new case of primary osteoma cutis observed in an adult. The monomelic feature of this case has not been reported previously. The patient was 76 years old and had multiple painless, stone-like formations at several sites on the left thigh and leg since the age of 40. Histological examination of skin biopsies showed a perfectly differentiated bone tissue in the dermal layer. There was no similar family history nor abnormal morphotype. Likewise, the absence of laboratory signs of pseudohypoparathyroidism, together with the late and spontaneous onset allowed us to eliminate hereditary Albright's osteodystropy or secondary osteomatosis due to a local pathological process. Despite the late onset, the monomelic character of the osteomas observed and the association of hemicorporeal hypertrophy and linear basocellular naevi reported in the literature would suggest a hamartomatous origin rather than a metaplasic process in this patient.

Adolescent

[Melanocytes in epiloia; ultrastructural aspects (about 7 cases) (author's transl)].

Hypopigmented macules of epiloia have been studied by photonic and electron microscopy in 7 cases. The number of melanocytes was not decreased but these cells were hypotrophic and had a low tyrosinae activity. The melanosomes were smaller in size and their maturation rate was greatly reduced; many abnormal round and granular melanosomes, phaeomelanosome-like, were observed. In one case, such abnormal melanocytes were also occasionally found in normally pigmented control skin.

Adolescent

[A human case of orf].

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Agricultural Workers' Diseases

[Aphthosis].

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Adult