[Possibilities for the production of tissue sections without the freezing process and embedding of tissue].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to F Wohlrab.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
An islet transplantation model was established with the two congeneic Lewis rat strains LEW.1W and LEW.1A, which were made diabetic by a single i.p. injection of 50 mg/kg b.w. streptozotocin. Isolated neonatal islets of the two strains served as a graft. Syngeneic transplantation into the spleen resulted in permanent graft survival and in normoglycemia of streptozotocin diabetic rats of the two strains. 200 days after transplantation functionally intact islets were demonstrable in the spleen by histological, histochemical and electron microscopical investigations. Histochemical findings indicate an activation of interdigitating reticular cells in the white pulp and of macrophages in the red pulp of the spleen as consequences of the islet transplantation. In addition a few electron microscopical findings concerning possible interactions between host plasma cells, lymphocytes and transplanted beta cells of islets are described and discussed.