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Biomedical subjects

F Weber

Publications and source records attributed to F Weber.

At least 289 records · Page 16Linked to original sources

Co-oxydation of a carotenoid by the enzyme lipoxygenase: influence on the formation of linoleic acid hydroperoxides.

A partially purified soybean lipoxygenase (L-3) was incubated for 15 min at pH 6.5 with linoleic acid and oxygen. Systems with and without the polyene glycoside crocin were compared. The system with crocin reacted with higher velocity with oxygen than did the control experiment without polyene. From the crocin 40% was destroyed. In the presence of crocin about 40% more linoleic acid hydroperoxides was formed than without the polyene but the linoleic acid break-down was equal in both experiments. L-3 peroxidises linoleic acid to 13L:13D:9L:9D-hydroperoxides in the proportions 43:11:21:25. In the presence of crocin the ratio of the isomers changed to 64:11:11:14.

Carotenoids↗

[Congenital craniopharyngioma].

Case report of a congenital craniopharyngioma in a full-term male stillborn infant. The tumour was remarkable for its size (10.5 X 9.5 X 6.5 cm) which exceeds those already published in the literature, and for the fact that hydrocephaly was minimal. Histologically, there were long, thin spaces lined by a cubic-like epithelium, and a large number of keratinized epidermic pearls containing peripheral keratohyalin granules. The clinical and neuropathological aspects of this tumour are compared with those of four other cases published in the literature.

Brain↗

[A case of Goldenhar syndrome: acute vitamin A intoxication in the mother during pregnancy].

The authors describe the case of a boy aged 2 1/2, who showed at birth a bilateral epibulbar dermoid, preauricular appendices on the left side and other malformations suggesting Goldenhar's syndrome. The history disclosed that in the second month of pregnancy the mother had accidentally swallowed 10 ml of an oily solution of Vitamin A during a laboratory manipulation. In their discussion, the autonrs analyse the teratogenic action of Vitamin A during embryonic development and review the aetiologies found in cases of Goldenhar's syndrome.

Abnormalities, Drug-Induced↗